Success Metrics

Clinical Success Rate
77.8%

Based on 28 completed trials

Completion Rate
78%(28/36)
Active Trials
30(29%)
Results Posted
50%(14 trials)
Terminated
8(8%)

Phase Distribution

Ph phase_2
27
26%
Ph phase_4
3
3%
Ph not_applicable
53
50%
Ph phase_3
2
2%
Ph early_phase_1
1
1%
Ph phase_1
11
10%

Phase Distribution

12

Early Stage

27

Mid Stage

5

Late Stage

Phase Distribution97 total trials
Early Phase 1First-in-human
1(1.0%)
Phase 1Safety & dosage
11(11.3%)
Phase 2Efficacy & side effects
27(27.8%)
Phase 3Large-scale testing
2(2.1%)
Phase 4Post-market surveillance
3(3.1%)
N/ANon-phased studies
53(54.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

62.2%

28 of 45 finished

Non-Completion Rate

37.8%

17 ended early

Currently Active

30

trials recruiting

Total Trials

105

all time

Status Distribution
Active(43)
Completed(28)
Terminated(17)
Other(17)

Detailed Status

Recruiting28
Completed28
unknown17
Not yet recruiting13
Withdrawn9
Terminated8

Development Timeline

Analytics

Development Status

Total Trials
105
Active
30
Success Rate
77.8%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (1.0%)
Phase 111 (11.3%)
Phase 227 (27.8%)
Phase 32 (2.1%)
Phase 43 (3.1%)
N/A53 (54.6%)

Trials by Status

recruiting2827%
terminated88%
active_not_recruiting22%
completed2827%
not_yet_recruiting1312%
unknown1716%
withdrawn99%

Recent Activity

Clinical Trials (105)

Showing 20 of 105 trialsScroll for more
NCT07726446Phase 2

Study on Sequential Cryoablation, Relaforp Alpha, and Chemotherapy for Bile Duct Tumors

Recruiting
NCT06253000Not Applicable

Radiofrequency and Cryoablation of the Posterior Wall of the Left Atrium

Recruiting
NCT07567027Not Applicable

Improving Cryoablation Efficacy With BARRigel Rectal Spacing (ICE-BARR)

Recruiting
NCT07676344Not Applicable

CRYO-TOUCH: Cryoablation of the Primary Breast Tumor in Metastatic Breast Cancer

Not Yet Recruiting
NCT06908538

Cryo NerVe Block Extremity AmputatioN RegIStry for Post Operative and pHantom Limb Pain

Recruiting
NCT07629206Not Applicable

Post-Marketing Study for Early-Stage Low-Risk Breast Cancer Treatment Using ProSense® Cryoablation (ChoICE Trial)

Not Yet Recruiting
NCT06246968Phase 1

A Study of Pembrolizumab and Cryoablation in People With Breast Cancer

Recruiting
NCT05779423Phase 2

Cryoablation+Ipilimumab+Nivolumab in Melanoma

Recruiting
NCT06224283

Radiomics Compared With Conventional Response Criteria for Predicting Progression of Desmoid Tumor After Cryoablation

Recruiting
NCT05972343

COOL-IT-PRO: Cryoablation of Breast Cancer in Non-surgical Patients

Recruiting
NCT07289984Not Applicable

Correlation Between Diagnostic Nerve Block Response and Cryoneurolysis Outcome in Chronic Musculoskeletal Disorders

Not Yet Recruiting
NCT06848881Not Applicable

Cryoablation vs Thoracoscopic Surgery for GGN

Recruiting
NCT07486674Not Applicable

Endoscopic and Cryoablation Denervation for Sacroiliac Joint Pain

Completed
NCT07450352Phase 2

SEED-CRYO: Sequential 125I Seed Implantation Followed by Cryoablation vs Single-Modality Local Therapy in Unresectable Solid Tumors

Not Yet Recruiting
NCT07437625Phase 2

Lesion-Allocated Therapy for Multiple Metastases and Tumor-Zoned Treatment for Bulky Tumors: A Phase II Study of Iodine-125 Seed Implantation Combined With Cryoablation in High-Burden Metastatic Disease

Not Yet Recruiting
NCT07416448Not Applicable

Neuroma-Associated Pain Management After Combat-Related Trauma in Ukraine

Recruiting
NCT06347874Phase 4

Cryo Rib Fracture Study

Recruiting
NCT07380789Not Applicable

Comprehensive Multicenter Study on the Management of Acute Pain Following Thoracic Combat-Related Trauma in Ukraine

Recruiting
NCT04339218Phase 3

Cryoablation in Combination (or Not) With Pembrolizumab and Pemetrexed-carboplatin in 1st-line Treatment for Patients With Metastatic Lung Adenocarcinoma

Recruiting
NCT04701918Phase 2

Cryoablation With Pembrolizumab Or Avelumab In Urothelial Carcinoma

Completed

Drug Details

Intervention Type
PROCEDURE
Total Trials
105