Success Metrics

Clinical Success Rate
100.0%

Based on 2 completed trials

Completion Rate
100%(2/2)
Active Trials
6(60%)
Results Posted
100%(2 trials)

Phase Distribution

Ph phase_2
2
20%
Ph phase_1
2
20%
Ph phase_3
6
60%

Phase Distribution

2

Early Stage

2

Mid Stage

6

Late Stage

Phase Distribution10 total trials
Phase 1Safety & dosage
2(20.0%)
Phase 2Efficacy & side effects
2(20.0%)
Phase 3Large-scale testing
6(60.0%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

50.0%

2 of 4 finished

Non-Completion Rate

50.0%

2 ended early

Currently Active

6

trials recruiting

Total Trials

10

all time

Status Distribution
Active(6)
Completed(2)
Terminated(2)

Detailed Status

Active, not recruiting6
Completed2
Withdrawn2

Development Timeline

Analytics

Development Status

Total Trials
10
Active
6
Success Rate
100.0%
Most Advanced
Phase 3

Trials by Phase

Phase 12 (20.0%)
Phase 22 (20.0%)
Phase 36 (60.0%)

Trials by Status

completed220%
active_not_recruiting660%
withdrawn220%

Recent Activity

Clinical Trials (10)

Showing 10 of 10 trials
NCT05075824Phase 2

A Study Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Crovalimab as Adjunct Treatment in Prevention of Vaso-Occlusive Episodes (VOE) in Sickle Cell Disease (SCD)

Completed
NCT04434092Phase 3

A Study Evaluating the Efficacy and Safety of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Not Previously Treated With Complement Inhibitors

Active Not Recruiting
NCT04432584Phase 3

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Complement Inhibitors

Active Not Recruiting
NCT04861259Phase 3

A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Adult and Adolescent Participants With Atypical Hemolytic Uremic Syndrome (aHUS)

Active Not Recruiting
NCT04958265Phase 3

A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Pediatric Participants With Atypical Hemolytic Uremic Syndrome (aHUS)

Active Not Recruiting
NCT07172022Phase 2

A Study to Evaluate Crovalimab in People With Antiphospholipid Syndrome (APS)

Withdrawn
NCT03157635Phase 1

Study to Assess Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Crovalimab in Healthy Volunteers and Participants With Paroxysmal Nocturnal Hemoglobinuria

Active Not Recruiting
NCT04654468Phase 3

A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Not Previously Treated With Complement Inhibition

Active Not Recruiting
NCT04912869Phase 1

A Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics and Efficacy of Crovalimab for the Management of Acute Uncomplicated Vaso-Occlusive Episodes (VOE) in Participants With Sickle Cell Disease (SCD).

Completed
NCT05494619Phase 3

A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Crovalimab in Participants With Guillain-Barré Syndrome (GBS)

Withdrawn

All 10 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
10