Success Metrics

Clinical Success Rate
87.0%

Based on 20 completed trials

Completion Rate
87%(20/23)
Active Trials
5(18%)
Results Posted
30%(6 trials)
Terminated
3(11%)

Phase Distribution

Ph phase_4
3
11%
Ph phase_1
20
71%
Ph phase_2
3
11%
Ph early_phase_1
1
4%

Phase Distribution

21

Early Stage

3

Mid Stage

3

Late Stage

Phase Distribution27 total trials
Early Phase 1First-in-human
1(3.7%)
Phase 1Safety & dosage
20(74.1%)
Phase 2Efficacy & side effects
3(11.1%)
Phase 4Post-market surveillance
3(11.1%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

87.0%

20 of 23 finished

Non-Completion Rate

13.0%

3 ended early

Currently Active

5

trials recruiting

Total Trials

28

all time

Status Distribution
Active(5)
Completed(20)
Terminated(3)

Detailed Status

Completed20
Recruiting4
Terminated3
Active, not recruiting1

Development Timeline

Analytics

Development Status

Total Trials
28
Active
5
Success Rate
87.0%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (3.7%)
Phase 120 (74.1%)
Phase 23 (11.1%)
Phase 43 (11.1%)

Trials by Status

active_not_recruiting14%
completed2071%
terminated311%
recruiting414%

Recent Activity

Clinical Trials (28)

Showing 20 of 28 trialsScroll for more
NCT02016924Phase 2

Study of Cobicistat-Boosted Atazanavir (ATV/co), Cobicistat-Boosted Darunavir (DRV/co) and Emtricitabine/Tenofovir Alafenamide (F/TAF) in Children With HIV

Active Not Recruiting
NCT06385119Phase 1

A Study of the Effects of Food and Cobicistat on Plixorafenib Pharmacokinetics in Healthy Participants.

Completed
NCT04065399Phase 1

A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

Recruiting
NCT04518228

Pharmacokinetic Properties of Antiretroviral and Anti-Tuberculosis Drugs During Pregnancy and Postpartum

Completed
NCT03480646Phase 1

ProSTAR: A Study Evaluating CPI-1205 in Patients With Metastatic Castration Resistant Prostate Cancer

Completed
NCT04718805Phase 1

A Study of Darunavir in the Presence of Cobicistat When Administered as a Fixed Dose Combination Under Fed Conditions

Completed
NCT04661397Phase 1

A Study in Healthy Participants to Assess the Effect of Darunavir, Emtricitabine, and Tenofovir Alafenamide in the Presence of Cobicistat as Fixed Dose Combination (Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide) Compared With Co-administration of the Separate Agents

Completed
NCT02578550Phase 1

A Bioequivalence Study of Darunavir, Emtricitabine, and Tenofovir Alafenamide, in the Presence of Cobicistat in Healthy Participants

Completed
NCT05458102Phase 1

Drug-Drug Interaction Study of Vesatolimod in Adults With HIV-1 Who Have Very Low or Undetectable Virus Levels

Terminated
NCT05748093Phase 4

Improving Osimertinib Exposure and Cost-effectiveness Using Pharmacokinetic Boosting With Cobicistat

Recruiting
NCT05078671Phase 4

Pharmacokinetic Boosting of Olaparib to Improve Exposure, Tolerance and Cost-effectiveness

Recruiting
NCT06014489Phase 2

A Trial to Assess Cobicistat Boosted Venetoclax in Combination With Azacitidine in Adult Patients With Newly Diagnosed AML

Recruiting
NCT03864406Phase 1

Impact of Steady State Cobicistat and Darunavir/Cobicistat on the Pharmacokinetics and Pharmacodynamics of Oral Anticoagulants (Rivaroxaban, Apixaban) in Health Volunteers

Completed
NCT05716854Phase 1

Electrophysiological Effects of Potential QT Prolonging Drugs

Completed
NCT05236738Phase 1

A Study to Compare the Drug Levels of Atazanavir and Cobicistat Between the Coadministration of Age-Appropriate Mini-Tablet Formulations and the Coadministration of the Individual Reference Products in Healthy Adults Under Fed Conditions

Completed
NCT03858491Early Phase 1

Pharmacokinetic Boosting of Osimertinib

Completed
NCT02307656Phase 1

Taste Properties of Atazanavir and Cobicistat

Completed
NCT04263350Phase 1

A Study to Examine the Acceptable Taste and to Estimate the Amount of Atazanavir and Cobicistat in the Body When Taken as a Combination Product Versus When Taken as Separate Products at the Same Time

Completed
NCT02565888Phase 1

A Drug-drug Interaction Study Between Daclatasvir and Atazanavir/Ritonavir or Atazanavir/Cobicistat

Completed
NCT04236453Phase 1

A Study in Healthy Participants to Assess the Effect of Darunavir, Emtricitabine, and Tenofovir Alafenamide in the Presence of Cobicistat When Administered as a Fixed Dose Combination (Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide) Compared to the Co-administration of the Separate Agents

Terminated

Drug Details

Intervention Type
DRUG
Total Trials
28