Success Metrics

Clinical Success Rate
96.2%

Based on 25 completed trials

Completion Rate
96%(25/26)
Active Trials
1(4%)
Results Posted
80%(20 trials)
Terminated
1(4%)

Phase Distribution

Ph phase_1
12
44%
Ph phase_2
15
56%

Phase Distribution

12

Early Stage

15

Mid Stage

0

Late Stage

Phase Distribution27 total trials
Phase 1Safety & dosage
12(44.4%)
Phase 2Efficacy & side effects
15(55.6%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

96.2%

25 of 26 finished

Non-Completion Rate

3.8%

1 ended early

Currently Active

1

trials recruiting

Total Trials

27

all time

Status Distribution
Active(1)
Completed(25)
Terminated(1)

Detailed Status

Completed25
Active, not recruiting1
Terminated1

Development Timeline

Analytics

Development Status

Total Trials
27
Active
1
Success Rate
96.2%
Most Advanced
Phase 2

Trials by Phase

Phase 112 (44.4%)
Phase 215 (55.6%)

Trials by Status

active_not_recruiting14%
completed2593%
terminated14%

Recent Activity

Clinical Trials (27)

Showing 20 of 27 trialsScroll for more
NCT01142388Phase 2

Paclitaxel With or Without Cixutumumab as Second-Line Therapy in Treating Patients With Metastatic Esophageal Cancer or Gastroesophageal Junction Cancer

Active Not Recruiting
NCT00617708Phase 1

S0727 Gemcitabine Hydrochloride and Erlotinib Hydrochloride With or Without Monoclonal Antibody Therapy in Treating Patients With Metastatic Pancreatic Cancer That Cannot Be Removed By Surgery

Completed
NCT00887159Phase 2

A Randomized Phase II Study of Cisplatin and Etoposide in Combination With Either Hedgehog Inhibitor GDC-0449 or IGF-1R MOAB IMC-A12 for Patients With Extensive Stage

Completed
NCT00684983Phase 2

Capecitabine and Lapatinib Ditosylate With or Without Cixutumumab in Treating Patients With Previously Treated HER2-Positive Stage IIIB-IV Breast Cancer

Completed
NCT01413191Phase 2

Cixutumumab in Treating Patients With Metastatic Melanoma of the Eye

Completed
NCT00781911Phase 2

A Study of Cixutumumab (IMC-A12) in Islet Cell Cancer

Completed
NCT01232452Phase 2

A Study in Non-Small Cell Lung Cancer

Completed
NCT01026623Phase 1

Cixutumumab and Temsirolimus in Treating Patients With Metastatic Prostate Cancer

Completed
NCT01263782Phase 2

BATTLE-FL: Front-Line Biomarker-Integrated Treatment Study in Non Small Cell Lung Cancer

Completed
NCT01007032Phase 1

A Study of IMC-A12 in Advanced Solid Tumors

Completed
NCT01614795Phase 2

Cixutumumab and Temsirolimus in Treating Younger Patients With Recurrent or Refractory Sarcoma

Completed
NCT00699491Phase 1

Cixutumumab and Temsirolimus in Treating Patients With Locally Recurrent or Metastatic Breast Cancer

Completed
NCT00955305Phase 2

Paclitaxel, Carboplatin, and Bevacizumab With or Without Cixutumumab in Treating Patients With Stage IV or Recurrent Non-small Cell Lung Cancer

Terminated
NCT01120236Phase 2

Bicalutamide and Goserelin or Leuprolide Acetate With or Without Cixutumumab in Treating Patients With Newly Diagnosed Metastatic Prostate Cancer

Completed
NCT01055314Phase 2

Temozolomide, Cixutumumab, and Combination Chemotherapy in Treating Patients With Metastatic Rhabdomyosarcoma

Completed
NCT01204476Phase 1

Cixutumumab, Everolimus, and Octreotide Acetate in Treating Patients With Advanced Low to Intermediate Grade Neuroendocrine Carcinoma

Completed
NCT00720174Phase 1

Cixutumumab and Doxorubicin Hydrochloride in Treating Patients With Unresectable, Locally Advanced, or Metastatic Soft Tissue Sarcoma

Completed
NCT01008566Phase 1

Cixutumumab and Sorafenib Tosylate in Treating Patients With Advanced Liver Cancer

Completed
NCT01061749Phase 1

Selumetinib and Cixutumumab in Treating Patients With Advanced Solid Malignancies

Completed
NCT00678769Phase 1

Cixutumumab and Temsirolimus in Treating Patients With Locally Advanced or Metastatic Cancer

Completed

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
27