Success Metrics

Clinical Success Rate
88.2%

Based on 15 completed trials

Completion Rate
88%(15/17)
Active Trials
5(19%)
Results Posted
60%(9 trials)
Terminated
2(7%)

Phase Distribution

Ph phase_3
8
30%
Ph phase_4
5
19%
Ph phase_2
3
11%
Ph early_phase_1
1
4%
Ph phase_1
1
4%
Ph not_applicable
9
33%

Phase Distribution

2

Early Stage

3

Mid Stage

13

Late Stage

Phase Distribution27 total trials
Early Phase 1First-in-human
1(3.7%)
Phase 1Safety & dosage
1(3.7%)
Phase 2Efficacy & side effects
3(11.1%)
Phase 3Large-scale testing
8(29.6%)
Phase 4Post-market surveillance
5(18.5%)
N/ANon-phased studies
9(33.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

75.0%

15 of 20 finished

Non-Completion Rate

25.0%

5 ended early

Currently Active

5

trials recruiting

Total Trials

27

all time

Status Distribution
Active(5)
Completed(15)
Terminated(5)
Other(2)

Detailed Status

Completed15
Recruiting3
Withdrawn3
Terminated2
Active, not recruiting2
unknown2

Development Timeline

Analytics

Development Status

Total Trials
27
Active
5
Success Rate
88.2%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (3.7%)
Phase 11 (3.7%)
Phase 23 (11.1%)
Phase 38 (29.6%)
Phase 45 (18.5%)
N/A9 (33.3%)

Trials by Status

recruiting311%
completed1556%
terminated27%
active_not_recruiting27%
unknown27%
withdrawn311%

Recent Activity

5 active trials
Showing 5 of 27
completednot_applicable

Citicoline and Filtration Surgery

NCT07567651
recruitingnot_applicable

Evaluate the Effects of Citicoline on Mood in Healthy Adults

NCT07089238
active_not_recruitingphase_1

Supplemental Citicoline Administration to Reduce Lung Injury Efficacy Trial (SCARLET)

NCT05881135
active_not_recruitingnot_applicable

Multimodal Morpho-functional Study in Glaucoma Patients-Citicoline Oral Solution

NCT05315206
completednot_applicable

Influence of Oral Treatment With Citicoline for the Prevention of Radiation Optic Neuropathy in Patients Treated for Uveal Melanomas With Proton Beam Therapy

NCT01338389
View all 27 trials

Clinical Trials (27)

Showing 20 of 27 trialsScroll for more
NCT07567651Not Applicable

Citicoline and Filtration Surgery

Completed
NCT07089238Not Applicable

Evaluate the Effects of Citicoline on Mood in Healthy Adults

Recruiting
NCT05881135Phase 1

Supplemental Citicoline Administration to Reduce Lung Injury Efficacy Trial (SCARLET)

Active Not Recruiting
NCT05315206Not Applicable

Multimodal Morpho-functional Study in Glaucoma Patients-Citicoline Oral Solution

Active Not Recruiting
NCT01338389Not Applicable

Influence of Oral Treatment With Citicoline for the Prevention of Radiation Optic Neuropathy in Patients Treated for Uveal Melanomas With Proton Beam Therapy

Completed
NCT02582905Phase 4

Clinical Medication Development for Bipolar Disorder and Alcohol Use Disorders

Completed
NCT03758118Not Applicable

Citicoline in Non-Arteritic Ischemic Optic Neuropathy

Completed
NCT05527106Not Applicable

Evaluation of the Effect of Citicoline and Docosahexaenoic Acid (DHA) on the Visual Function of Patients With Glaucoma

Completed
NCT04802785Phase 2

The Impact of Air Travel on Passenger Cognitive Functions

Unknown
NCT00404729Phase 4

Neural Conduction Along the Visual Pathways After Oral Treatment With Citicoline in Patients With Optic Nerve Diseases

Completed
NCT04003090Not Applicable

Citicoline Concentration in Human Vitreous

Completed
NCT03949049Phase 3

Citicoline as Neuroprotector in Neonates Exposed to Hypoxia

Recruiting
NCT03966170Phase 3

Citicoline as Neuroprotector in Preterm

Recruiting
NCT01582113Early Phase 1

Cognizin Citicoline Dosing in a Healthy Adolescent Male Population

Completed
NCT02074735Phase 4

Citicoline for Alcohol Dependence

Completed
NCT00619723Phase 4

Citicoline for Bipolar 1 Disorder and Cocaine Dependence

Completed
NCT02840591Phase 4

Ramelteon and Citicoline for Delirium

Withdrawn
NCT03181646Phase 3

Role of Citicoline in Treatment of Newborns With Hypoxic Ischemic Encephalopathy

Unknown
NCT00950352Phase 3

Citicoline Treatment of Methamphetamine Dependence

Completed
NCT01515917Not Applicable

Citicoline and Omega-3 Fatty Acid Effects in Veterans With Traumatic Brain Injury (TBI)

Withdrawn

Drug Details

Intervention Type
DEVICE
Total Trials
27