Success Metrics

Clinical Success Rate
85.7%

Based on 12 completed trials

Completion Rate
86%(12/14)
Active Trials
2(11%)
Results Posted
42%(5 trials)
Terminated
2(11%)

Phase Distribution

Ph early_phase_1
1
6%
Ph not_applicable
11
61%
Ph phase_1
5
28%
Ph phase_2
1
6%

Phase Distribution

6

Early Stage

1

Mid Stage

0

Late Stage

Phase Distribution18 total trials
Early Phase 1First-in-human
1(5.6%)
Phase 1Safety & dosage
5(27.8%)
Phase 2Efficacy & side effects
1(5.6%)
N/ANon-phased studies
11(61.1%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

80.0%

12 of 15 finished

Non-Completion Rate

20.0%

3 ended early

Currently Active

2

trials recruiting

Total Trials

18

all time

Status Distribution
Active(2)
Completed(12)
Terminated(3)
Other(1)

Detailed Status

Completed12
Terminated2
Recruiting1
unknown1
Active, not recruiting1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
18
Active
2
Success Rate
85.7%
Most Advanced
Phase 2

Trials by Phase

Early Phase 11 (5.6%)
Phase 15 (27.8%)
Phase 21 (5.6%)
N/A11 (61.1%)

Trials by Status

recruiting16%
unknown16%
terminated211%
active_not_recruiting16%
withdrawn16%
completed1267%

Recent Activity

Clinical Trials (18)

Showing 18 of 18 trials
NCT07108166Not Applicable

Symptoms and Functions in Patients With COPD and Chronic Bronchitis Switching From CIG to THS

Active Not Recruiting
NCT07459712Not Applicable

Pharmacokinetics and Pharmacodynamics of THS With LEVIA Compared to THS With TEREA and to Cigarettes

Completed
NCT06315881Phase 2

Informing Oral Nicotine Pouch Regulations to Promote Public Health

Recruiting
NCT03691350Early Phase 1

Bronchoscopy in Determining the Effect of E-Cigarette Smoking on Biomarkers in the Lungs

Completed
NCT02964182Not Applicable

Very Low Nicotine Content Cigarettes and E-Cigarettes in Promoting Smoking Cessation in Daily and Intermittent Cigarette Smokers

Completed
NCT05335915Phase 1

Acute Pharmacokinetic and Pharmacodynamic Effects of "Tobacco-Free" Oral Nicotine Pouches in Smokers

Completed
NCT03837704Not Applicable

Comparison of Abdominal Aortic Aneurysm Growth in Adult Smoking Patients Who Either Switch to IQOS, Continue Smoking, or Quit Smoking.

Completed
NCT03398876Phase 1

A Study to Assess the Nicotine Pharmacokinetics, Tolerability and Safety With a New Oral Nicotine Replacement Product in Healthy Japanese Smokers

Completed
NCT05566678Not Applicable

Effect of Switching From Cigarette Smoking to THS on Systemic Endothelial Function in Subjects With Established Atherosclerotic Disease

Withdrawn
NCT05569005Not Applicable

Effect of Switching From Cigarette Smoking to THS on Disease Progression in Mild to Moderate COPD Subjects With Chronic Bronchitis Symptoms.

Terminated
NCT03364751Not Applicable

Effect of Switching From Cigarette Smoking to the Use of IQOS on Periodontitis Treatment Outcome

Completed
NCT03166787Phase 1

Hookah Smoking, Carbon Monoxide, and Coronary Endothelial Function

Terminated
NCT03086707Not Applicable

Prefatory Study to Explore Changes in Nasal Mucociliary Clearance and to Standardize Nasal Scraping Procedure

Completed
NCT02963467Not Applicable

Effect of Smoking on Ventilation-Perfusion Ratio

Unknown
NCT02514720Not Applicable

Nicotine Metabolizers and [11C]-(+)-PHNO

Completed
NCT02794220Phase 1

A Study of Blood Levels of Nicotine Following an Electronic Cigarette

Completed
NCT02102191Not Applicable

Acute Physiological Effects of Electronic Sigarette vs Cigarette Smoking

Completed
NCT00992550Phase 1

Comparison of Hookah and Cigarette Smoking

Completed

All 18 trials loaded

Drug Details

Intervention Type
OTHER
Total Trials
18