Success Metrics

Active Trials
13(87%)

Phase Distribution

Ph phase_1
9
60%
Ph early_phase_1
1
7%
Ph phase_2
5
33%

Phase Distribution

10

Early Stage

5

Mid Stage

0

Late Stage

Phase Distribution15 total trials
Early Phase 1First-in-human
1(6.7%)
Phase 1Safety & dosage
9(60.0%)
Phase 2Efficacy & side effects
5(33.3%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

0.0%

0 of 0 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

13

trials recruiting

Total Trials

15

all time

Status Distribution
Active(13)
Other(2)

Detailed Status

Recruiting7
Active, not recruiting6
Suspended1
unknown1

Development Timeline

Analytics

Development Status

Total Trials
15
Active
13
Success Rate
N/A
Most Advanced
Phase 2

Trials by Phase

Early Phase 11 (6.7%)
Phase 19 (60.0%)
Phase 25 (33.3%)

Trials by Status

suspended17%
active_not_recruiting640%
unknown17%
recruiting747%

Recent Activity

Clinical Trials (15)

Showing 15 of 15 trials
NCT06784726Phase 2

Odronextamab for Relapsed and Refractory Large B-cell Lymphomas Before CAR-T

Recruiting
NCT03696030Phase 1

HER2-CAR T Cells in Treating Patients With Recurrent Brain or Leptomeningeal Metastases

Active Not Recruiting
NCT06104592Phase 2

Single-Arm Comprehensive Ablative Bridging Irradiation I Prior to CD19 CAR-T In High-Risk R/R LBCL

Recruiting
NCT05800405Early Phase 1

Evaluation of Bridging Radiation Therapy Before CAR T-Cell Infusion for the Treatment of Relapsed or Refractory Large B-Cell Lymphoma

Recruiting
NCT06834373Phase 2

Golcadomide and Rituximab as Bridging Therapy for Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphoma Before CAR T-cell Therapy

Recruiting
NCT03277729Phase 1

A Phase I/II Study to Evaluate the Safety of Cellular Immunotherapy Using Autologous T Cells Engineered to Express a CD20-Specific Chimeric Antigen Receptor for Patients With Relapsed or Refractory B Cell Non-Hodgkin Lymphomas

Active Not Recruiting
NCT03233854Phase 1

CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells With or Without NKTR-255 in Adults With Recurrent or Refractory B Cell Malignancies

Active Not Recruiting
NCT05993611Phase 1

Allogeneic CD6 Chimeric Antigen Receptor T Regulatory Cells (CD6-CAR Tregs) for the Treatment of Patients With Chronic Graft Versus Host Disease After Allogeneic Hematopoietic Cell Transplantation

Suspended
NCT06854159Phase 2

Odronextamab for the Treatment of Relapsed and Refractory Diffuse Large B-cell Lymphoma Before and After Chimeric Antigen Receptor T-cell Therapy

Recruiting
NCT04007029Phase 1

Modified Immune Cells (CD19/CD20 CAR-T Cells) in Treating Patients With Recurrent or Refractory B-Cell Lymphoma or Chronic Lymphocytic Leukemia

Active Not Recruiting
NCT03241940Phase 1

Study of CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults w/ Recurrent or Refractory B Cell Malignancies

Active Not Recruiting
NCT06815029Phase 1

Intracranial Genetically Modified Immune Cells (TGFβR2KO/IL13Rα2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant Astrocytoma

Recruiting
NCT05202782Phase 2

Zanubrutinib and CAR T-cell Therapy for the Treatment of Recurrent or Refractory Aggressive B-cell Non-Hodgkin's Lymphoma or Transformed Indolent B-cell Lymphoma

Active Not Recruiting
NCT05052528Phase 1

Fludarabine and Cyclophosphamide With or Without Rituximab Before CD19 Chimeric Antigen Receptor T Cells for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Recruiting
NCT03467256Phase 1

CD19 T-CAR for Treatment of Children and Young Adults With r/r B-ALL

Unknown

All 15 trials loaded

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
15