Success Metrics

Clinical Success Rate
60.0%

Based on 3 completed trials

Completion Rate
60%(3/5)
Active Trials
20(77%)
Results Posted
167%(5 trials)
Terminated
2(8%)

Phase Distribution

Ph phase_3
2
8%
Ph phase_2
16
62%
Ph phase_1
8
31%

Phase Distribution

8

Early Stage

16

Mid Stage

2

Late Stage

Phase Distribution26 total trials
Phase 1Safety & dosage
8(30.8%)
Phase 2Efficacy & side effects
16(61.5%)
Phase 3Large-scale testing
2(7.7%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

50.0%

3 of 6 finished

Non-Completion Rate

50.0%

3 ended early

Currently Active

20

trials recruiting

Total Trials

26

all time

Status Distribution
Active(20)
Completed(3)
Terminated(3)

Detailed Status

Active, not recruiting13
Recruiting7
Completed3
Terminated2
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
26
Active
20
Success Rate
60.0%
Most Advanced
Phase 3

Trials by Phase

Phase 18 (30.8%)
Phase 216 (61.5%)
Phase 32 (7.7%)

Trials by Status

withdrawn14%
active_not_recruiting1350%
recruiting727%
completed312%
terminated28%

Recent Activity

Clinical Trials (26)

Showing 20 of 26 trialsScroll for more
NCT06732401Phase 3

Testing the Addition of AZD6738 (Ceralasertib) to Immunotherapy to Increase Time Without Cancer for Patients With Non-Small Cell Lung Cancer

Active Not Recruiting
NCT03878095Phase 2

Testing Olaparib and AZD6738 in IDH1 and IDH2 Mutant Tumors

Active Not Recruiting
NCT04704661Phase 1

Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial

Active Not Recruiting
NCT03682289Phase 2

Ceralasertib (AZD6738) Alone and in Combination With Olaparib or Durvalumab in Patients With Solid Tumors

Active Not Recruiting
NCT03328273Phase 1

A Study of AZD6738 and Acalabrutinib in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)

Active Not Recruiting
NCT05450692Phase 3

A Phase III Study of Ceralasertib Plus Durvalumab Versus Docetaxel in Patients With Non Small Cell Lung Cancer (NSCLC) Whose Disease Progressed On or After Prior Anti PD (L)1 Therapy And Platinum Based Chemotherapy

Active Not Recruiting
NCT06769126Phase 2

Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study

Recruiting
NCT05514132Phase 1

A Study to Evaluate the Safety and Pharmacokinetics of Ceralasertib in Combination With Durvalumab in Chinese Patients With Advanced Solid Tumours

Active Not Recruiting
NCT04090567Phase 2

Olaparib With Cediranib or AZD6738 for the Treatment of Advanced or Metastatic Germline BRCA Mutated Breast Cancer

Recruiting
NCT05941897Phase 2

A Study to Investigate Efficacy and Safety of Ceralasertib Plus Durvalumab in Participants Aged ≥ 18 Years With Advanced or Metastatic Non-small Cell Lung Cancer Whose Disease Progressed on or After Prior Anti-PD-(L)1 Therapy and Platinum-based Chemotherapy

Active Not Recruiting
NCT03801369Phase 2

AMTEC IIT: Phase 2 Multiarm Study in TNBC

Terminated
NCT04417062Phase 2

Olaparib With Ceralasertib in Recurrent Osteosarcoma

Active Not Recruiting
NCT04065269Phase 2

ATr Inhibitor in Combination With Olaparib/Durvalumab (MEDI4736) in Gynaecological Cancers With ARId1A Loss or no Loss

Active Not Recruiting
NCT03579316Phase 2

Adavosertib With or Without Olaparib in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Active Not Recruiting
NCT06929260Phase 1

A Study to Evaluate the Effect of Ceralasertib on Drug X, Drug Y and Drug Z

Terminated
NCT02813135Phase 1

European Proof-of-Concept Therapeutic Stratification Trial of Molecular Anomalies in Relapsed or Refractory Tumors

Recruiting
NCT04699838Phase 2

Chemo-Immunotherapy Followed by Durvalumab and Ceralasertib in Treatment Naïve Patients With Extensive Stage Small Cell Lung Cancer

Recruiting
NCT04550104Phase 1

A Platform Study of Novel Agents in Combination With Radiotherapy in NSCLC

Recruiting
NCT06680050Phase 2

Phase II Study of Radiotherapy Followed by Durvalumab and Ceralasertib in Stage III NSCLC Patients With Thoracic Relapses +/- Oligometastases After PACIFIC Regimen

Recruiting
NCT03334617Phase 2

Phase II Umbrella Study of Novel Anti-cancer Agents in Participants With NSCLC Who Progressed on an Anti-PD-1/PD-L1 Containing Therapy

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
26