Success Metrics

Clinical Success Rate
65.5%

Based on 19 completed trials

Completion Rate
66%(19/29)
Active Trials
105(63%)
Results Posted
68%(13 trials)
Terminated
10(6%)

Phase Distribution

Ph phase_3
11
7%
Ph not_applicable
1
1%
Ph phase_1
61
36%
Ph phase_2
88
52%

Phase Distribution

61

Early Stage

88

Mid Stage

11

Late Stage

Phase Distribution161 total trials
Phase 1Safety & dosage
61(37.9%)
Phase 2Efficacy & side effects
88(54.7%)
Phase 3Large-scale testing
11(6.8%)
N/ANon-phased studies
1(0.6%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

54.3%

19 of 35 finished

Non-Completion Rate

45.7%

16 ended early

Currently Active

105

trials recruiting

Total Trials

168

all time

Status Distribution
Active(125)
Completed(19)
Terminated(16)
Other(8)

Detailed Status

Recruiting72
Active, not recruiting33
Not yet recruiting19
Completed19
Terminated10
Withdrawn6

Development Timeline

Analytics

Development Status

Total Trials
168
Active
105
Success Rate
65.5%
Most Advanced
Phase 3

Trials by Phase

Phase 161 (37.9%)
Phase 288 (54.7%)
Phase 311 (6.8%)
N/A1 (0.6%)

Trials by Status

unknown53%
not_yet_recruiting1911%
completed1911%
withdrawn64%
recruiting7243%
suspended32%
active_not_recruiting3320%
enrolling_by_invitation11%
terminated106%

Recent Activity

Clinical Trials (168)

Showing 20 of 168 trialsScroll for more
NCT07422363Phase 1

Testing the Combination of Anti-cancer Drugs Actimab-A and Cemiplimab (REGN2810) to Improve Outcomes for Patients With Recurrent Glioblastoma

Not Yet Recruiting
NCT07058012Phase 2

A Phase II Platform Study to Evaluate Treatment With Cemiplimab Monotherapy or Cemiplimab Plus Fianlimab or Other Novel Combinations in Patients With Colorectal Cancer With Minimal Residual Disease Following Definitive Surgery and Chemotherapy (EMPIRE)

Recruiting
NCT07281417Phase 2

Testing the Addition of Cemiplimab (REGN2810) to Chemotherapy Treatment Given Prior to Surgery in Patients With Sinonasal Squamous Cell Carcinoma

Recruiting
NCT06900595Phase 2

Testing the Addition of an Anti-Cancer Drug, Cabozantinib to the Immunotherapy Drug Cemiplimab (REGN2810), in Adolescents and Adults With Advanced Adrenocortical Cancer

Recruiting
NCT05929664Phase 2

Cemiplimab Plus Fianlimab for the Treatment of Locally Advanced Head and Neck Basal Cell Carcinoma Before Surgery

Suspended
NCT06508463Phase 1

Intravenous Vesicular Stomatitis Virus in Patients With Peripheral T-cell Lymphoma

Recruiting
NCT03017820Phase 1

A Vaccine (VSV-hIFNβ-NIS) With or Without Cyclophosphamide and Combinations of Ipilimumab, Nivolumab, and Cemiplimab in Treating Relapsed or Refractory Multiple Myeloma, Acute Myeloid Leukemia or Lymphoma

Recruiting
NCT04916002Phase 2

A Trial To Find Out If Vidutolimod Together With Cemiplimab Is Safe And If It Works In Adult Participants With Advanced Cancer Or Metastatic Cancer

Terminated
NCT06585410Phase 3

Study of Intralesional Cemiplimab in Adult Patients With Early Stage Cutaneous Squamous Cell Carcinoma

Recruiting
NCT07527325Phase 2

Fianlimab&Cemiplimab as TotalNeoadj The (TNT) ForMelanoma

Not Yet Recruiting
NCT06444880Phase 2

Phase II Trial of Ubamatamab Alone or in Combination With Cemiplimab in MUC16-Expressing SMARCB1-Deficient Malignancies

Recruiting
NCT07620548Phase 2

Laser Interstitial Thermal Therapy (LiTT) With Cemiplimab or Other Chemotherapy in Recurrent Glioblastomas

Not Yet Recruiting
NCT02651662Phase 1

A Study to Learn How Safe and Tolerable Odronextamab and Cemiplimab Are in Adult Patients With B-cell Malignancies

Completed
NCT06980038Phase 2

Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer

Recruiting
NCT06931717Phase 3

A Clinical Study to Assess the Efficacy of Adjuvant Immunotherapy With Cemiplimab in Patients With Surgically Removed Non-small Cell Lung Cancer Who Have Not Received Prior Chemotherapy

Recruiting
NCT04315701Phase 2

A PD-1 Checkpoint Inhibitor (Cemiplimab) for High-Risk Localized, Locally Recurrent, or Regionally Advanced Skin Cancer

Active Not Recruiting
NCT05882734Phase 1

Tuvusertib (M1774) in Combination With Cemiplimab in Participants With Non-Squamous NSCLC (DDRiver NSCLC 322)

Active Not Recruiting
NCT06161441Phase 2

A Trial to Learn if the Combination of Fianlimab, Cemiplimab, and Chemotherapy is Safe and Works Better Than the Combination of Cemiplimab and Chemotherapy in Adult Patients With Non-Small Cell Lung Cancer That Can be Treated With Surgery

Active Not Recruiting
NCT07404332Phase 1

5-Azacitidine Plus PD-1/PD-L1 Inhibitor With PD-1/PD-L1 Refractory Tumors

Recruiting
NCT06860815Phase 2

Cemiplimab and Transarterial Radioembolization With Y-90 SIR-S Spheres for the Treatment of Liver Directed Metastatic Breast Cancer

Recruiting

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
168