Success Metrics

Clinical Success Rate
85.7%

Based on 6 completed trials

Completion Rate
86%(6/7)
Active Trials
1(13%)
Results Posted
0%(0 trials)
Terminated
1(13%)

Phase Distribution

Ph phase_1
7
88%
Ph phase_3
1
13%

Phase Distribution

7

Early Stage

0

Mid Stage

1

Late Stage

Phase Distribution8 total trials
Phase 1Safety & dosage
7(87.5%)
Phase 3Large-scale testing
1(12.5%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

85.7%

6 of 7 finished

Non-Completion Rate

14.3%

1 ended early

Currently Active

1

trials recruiting

Total Trials

8

all time

Status Distribution
Active(1)
Completed(6)
Terminated(1)

Detailed Status

Completed6
Recruiting1
Terminated1

Development Timeline

Analytics

Development Status

Total Trials
8
Active
1
Success Rate
85.7%
Most Advanced
Phase 3

Trials by Phase

Phase 17 (87.5%)
Phase 31 (12.5%)

Trials by Status

recruiting113%
terminated113%
completed675%

Recent Activity

1 active trials
Showing 5 of 8
completedphase_1

Plasma and Intrapulmonary Pharmacokinetics of Ceftibuten and Ledaborbactam in Healthy Male and Female Participants 18 to ≤55 Years of Age

NCT06665555
recruitingphase_1

Safety and PK of Ceftibuten-ledaborbactam Etzadroxil Fixed-dose Combination

NCT06733675
completedphase_1

P1, DDI & MAD PK and Safety Study of Xeruborbactam Oral Prodrug in Combo With Ceftibuten in Healthy Participants

NCT06079775
completedphase_1

Ceftibuten/VNRX-7145 in Participants With Varying Degrees of Renal Function

NCT05488678
completedphase_1

Food Effect on Ceftibuten/VNRX-7145 in Healthy Participants

NCT05527834
View all 8 trials

Clinical Trials (8)

Showing 8 of 8 trials
NCT06665555Phase 1

Plasma and Intrapulmonary Pharmacokinetics of Ceftibuten and Ledaborbactam in Healthy Male and Female Participants 18 to ≤55 Years of Age

Completed
NCT06733675Phase 1

Safety and PK of Ceftibuten-ledaborbactam Etzadroxil Fixed-dose Combination

Recruiting
NCT06079775Phase 1

P1, DDI & MAD PK and Safety Study of Xeruborbactam Oral Prodrug in Combo With Ceftibuten in Healthy Participants

Completed
NCT05488678Phase 1

Ceftibuten/VNRX-7145 in Participants With Varying Degrees of Renal Function

Completed
NCT05527834Phase 1

Food Effect on Ceftibuten/VNRX-7145 in Healthy Participants

Completed
NCT06593054Phase 1

To Learn How Different Forms of Study Medicine Are Taken up Into the Blood and the Effect of Food on Study Medicine in Healthy Adults

Completed
NCT06157242Phase 1

PK & Safety Study of Xeruborbactam Oral Prodrug Combined With Ceftibuten in Participants With Renal Impairment

Completed
NCT00724256Phase 3

Short-term Antibiotic Therapy for Pyelonephritis in Childhood

Terminated

All 8 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
8