Success Metrics

Clinical Success Rate
92.9%

Based on 13 completed trials

Completion Rate
93%(13/14)
Active Trials
3(16%)
Results Posted
46%(6 trials)
Terminated
1(5%)

Phase Distribution

Ph phase_3
3
16%
Ph phase_4
4
21%
Ph phase_2
5
26%
Ph phase_1
5
26%

Phase Distribution

5

Early Stage

5

Mid Stage

7

Late Stage

Phase Distribution17 total trials
Phase 1Safety & dosage
5(29.4%)
Phase 2Efficacy & side effects
5(29.4%)
Phase 3Large-scale testing
3(17.6%)
Phase 4Post-market surveillance
4(23.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

92.9%

13 of 14 finished

Non-Completion Rate

7.1%

1 ended early

Currently Active

3

trials recruiting

Total Trials

19

all time

Status Distribution
Active(4)
Completed(13)
Terminated(1)
Other(1)

Detailed Status

Completed13
Recruiting3
Terminated1
Not yet recruiting1
unknown1

Development Timeline

Analytics

Development Status

Total Trials
19
Active
3
Success Rate
92.9%
Most Advanced
Phase 4

Trials by Phase

Phase 15 (29.4%)
Phase 25 (29.4%)
Phase 33 (17.6%)
Phase 44 (23.5%)

Trials by Status

completed1368%
terminated15%
not_yet_recruiting15%
recruiting316%
unknown15%

Recent Activity

Clinical Trials (19)

Showing 19 of 19 trials
NCT07759453Phase 3

Targeted Versus Standard Peri-operative Antibiotic Prophylaxis in Patients Colonized With Carbapenemase Producing Enterobacterales Undergoing Liver Transplantation

Not Yet Recruiting
NCT07465432Phase 4

Pharmacokinetic Analysis of Cefiderocol in Patients With Acute Burn Injuries

Recruiting
NCT06086626Phase 2

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Cefiderocol in Hospitalized Neonates and Infants

Completed
NCT04335539Phase 2

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of Cefiderocol in Hospitalized Pediatric Participants

Completed
NCT06547554Phase 1

A DDI Study to Investigate PK and Safety of Cefiderocol in Combination With Xeruborbactam in Healthy Adult Participants

Completed
NCT05922124Phase 4

Cefiderocol and Ampicillin-sulbactam vs. Colistin +/- Meropenem for Carbapenem Resistant A. Baumannii

Recruiting
NCT07004049Phase 4

Optimising TREATment for Severe Gram-Negative Bacterial Infections

Recruiting
NCT04215991Phase 2

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Cefiderocol in Hospitalized Pediatric Participants

Completed
NCT05373615Phase 1

Cefiderocol Plasma Concentrations in Patients Receiving Renal Replacement Therapy

Completed
NCT05314764Phase 4

Cefiderocol Pharmacokinetics in Adult Patients With Cystic Fibrosis

Completed
NCT04995835Phase 1

Cefiderocol PK in Patients on ECMO

Completed
NCT03869437Phase 2

RCT Cefiderocol vs BAT for Treatment of Gram Negative BSI

Completed
NCT05395104Phase 1

A Study to Assess the Effect of Cefiderocol on the Pharmacokinetics (PK) of Midazolam in Healthy Participants

Completed
NCT05789199

Use of Cefiderocol in the Management of Gram-Negative Infections

Completed
NCT02714595Phase 3

Study of Cefiderocol (S-649266) or Best Available Therapy for the Treatment of Severe Infections Caused by Carbapenem-resistant Gram-negative Pathogens

Completed
NCT03032380Phase 3

Clinical Study of Cefiderocol (S-649266) for the Treatment of Nosocomial Pneumonia Caused by Gram-negative Pathogens

Completed
NCT03862040Phase 1

Cefiderocol Concentrations in the Lungs of Hospitalized Patients With Bacterial Pneumonia

Terminated
NCT03780140

Expanded Access to Cefiderocol for the Intravenous Treatment of Severe Gram Negative Bacterial Infections

Unknown
NCT02321800Phase 2

A Study of Efficacy and Safety of Intravenous Cefiderocol (S-649266) Versus Imipenem/Cilastatin in Complicated Urinary Tract Infections

Completed

All 19 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
19