Success Metrics

Clinical Success Rate
81.8%

Based on 9 completed trials

Completion Rate
82%(9/11)
Active Trials
2(14%)
Results Posted
44%(4 trials)
Terminated
2(14%)

Phase Distribution

Ph phase_1
12
86%
Ph phase_2
2
14%

Phase Distribution

12

Early Stage

2

Mid Stage

0

Late Stage

Phase Distribution14 total trials
Phase 1Safety & dosage
12(85.7%)
Phase 2Efficacy & side effects
2(14.3%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

75.0%

9 of 12 finished

Non-Completion Rate

25.0%

3 ended early

Currently Active

2

trials recruiting

Total Trials

14

all time

Status Distribution
Active(2)
Completed(9)
Terminated(3)

Detailed Status

Completed9
Terminated2
Active, not recruiting1
Withdrawn1
Recruiting1

Development Timeline

Analytics

Development Status

Total Trials
14
Active
2
Success Rate
81.8%
Most Advanced
Phase 2

Trials by Phase

Phase 112 (85.7%)
Phase 22 (14.3%)

Trials by Status

completed964%
active_not_recruiting17%
terminated214%
withdrawn17%
recruiting17%

Recent Activity

Clinical Trials (14)

Showing 14 of 14 trials
NCT04884035Phase 1

Study of Safety and Efficacy of Iberdomide (CC-220) and CC-99282 Combined With R-CHOP to Treat Lymphoma

Recruiting
NCT02773030Phase 1

A Study to Determine Dose, Safety, Tolerability and Efficacy of CC-220 Monotherapy, and in Combination With Other Treatments in Subjects With Multiple Myeloma

Active Not Recruiting
NCT04855136Phase 1

Safety and Efficacy of bb2121 (Ide-cel) Combinations in Multiple Myeloma

Terminated
NCT04464798Phase 1

A Dose Finding and Safety Study of CC-220, Alone and in Combination With an Anti-CD20 Monoclonal Antibody (mAb) in Subjects With Relapsed or Refractory Lymphomas

Terminated
NCT03310619Phase 1

A Safety and Efficacy Trial of JCAR017 Combinations in Subjects With Relapsed/Refractory B-cell Malignancies

Completed
NCT03161483Phase 2

A Study to Evaluate the Efficacy and Safety of CC-220 in Subjects With Active Systemic Lupus Erythematosus

Completed
NCT04882163Phase 1

Study to Evaluate Tolerability of Iberdomide (CC-220) in Combination With Polatuzumab Vedotin Plus Rituximab or Tafasitamab or Rituximab Plus Chemotherapy in B-cell Lymphoma

Withdrawn
NCT03824678Phase 1

Evaluate the Pharmacokinetics of CC-220 in Subjects With Mild, Moderate, or Severe Hepatic Impairment Compared With Healthy Subjects

Completed
NCT02185040Phase 2

A Pilot Study of CC-220 to Treat Systemic Lupus Erythematosus.

Completed
NCT01733875Phase 1

2-part Study to Assess Safety, Pharmacokinetics & Pharmacodynamics of CC-220 & Effect of Food on CC-220 in Healthy Subjects

Completed
NCT03294603Phase 1

Radiolabeled Study of CC-220 in Healthy Male Subjects

Completed
NCT03135509Phase 1

A Study to Assess the Relative Bioavailability of a New CC-220 Capsule Formulation, Compared to a Reference CC-220 Capsule Formulation, in Healthy Adult Subjects

Completed
NCT02820935Phase 1

Study to Evaluate the Effect of Cytochrome P450 (CYP) 3A Inhibition and Induction on the Pharmacokinetics of CC-220 in Healthy Subjects

Completed
NCT02034773Phase 1

3-part Study to Evaluate Safety, Tolerability, Pharmacokinetics & Pharmacodynamics of Multiple Doses of CC-220 and Relative Bioavailability of a Formulated CC-220 Capsule

Completed

All 14 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
14