Biological
CART 19
CART 19 is a biological therapy with 3 clinical trials. Historical success rate of 33.3%.
Total Trials
3
Max Phase
—
Type
BIOLOGICAL
Molecule
—
Success Metrics
Clinical Success Rate
33.3%
Based on 1 completed trials
Completion Rate
33%(1/3)
Active Trials
0(0%)
Results Posted
100%(1 trials)
Terminated
2(67%)
Phase Distribution
Ph early_phase_1
1
33%
Ph phase_1
1
33%
Ph phase_2
1
33%
Phase Distribution
2
Early Stage
1
Mid Stage
0
Late Stage
Phase Distribution3 total trials
Early Phase 1First-in-human
1(33.3%)
Phase 1Safety & dosage
1(33.3%)
Phase 2Efficacy & side effects
1(33.3%)
Highest Phase Reached
Phase 2Trial Status & Enrollment
Completion Rate
33.3%
1 of 3 finished
Non-Completion Rate
66.7%
2 ended early
Currently Active
0
trials recruiting
Total Trials
3
all time
Status Distribution
Completed(1)
Terminated(2)
Detailed Status
Terminated2
Completed1
Development Timeline
Analytics
Development Status
Total Trials
3
Active
0
Success Rate
33.3%
Most Advanced
Phase 2
Trials by Phase
Early Phase 11 (33.3%)
Phase 11 (33.3%)
Phase 21 (33.3%)
Trials by Status
terminated267%
completed133%
Recent Activity
0 active trials
Showing 3 of 3
terminatedphase_2
CART19 in Adult Patients With Minimal Residual Disease During Upfront Treatment for ALL
NCT02935543
terminatedearly_phase_1
Pilot Trial Of Autologous T Cells Engineered To Express Anti-CD19 Chimeric Antigen Receptor (CART19)In Combination With Ibrutinib In Patients With Relapsed Or Refractory CD19+ Chronic Lymphocytic Leukemia (CLL)Or Small Lymphocytic Lymphoma (SLL)
NCT02640209
completedphase_1
Study of the Tocilizumab Optimization Timing for CART19 Associated Cytokine Release Syndrome
NCT02906371
Clinical Trials (3)
Showing 3 of 3 trials
NCT02935543Phase 2
CART19 in Adult Patients With Minimal Residual Disease During Upfront Treatment for ALL
NCT02640209Early Phase 1
Pilot Trial Of Autologous T Cells Engineered To Express Anti-CD19 Chimeric Antigen Receptor (CART19)In Combination With Ibrutinib In Patients With Relapsed Or Refractory CD19+ Chronic Lymphocytic Leukemia (CLL)Or Small Lymphocytic Lymphoma (SLL)
NCT02906371Phase 1
Study of the Tocilizumab Optimization Timing for CART19 Associated Cytokine Release Syndrome
All 3 trials loaded
Drug Details
- Intervention Type
- BIOLOGICAL
- Total Trials
- 3