Success Metrics

Clinical Success Rate
88.9%

Based on 8 completed trials

Completion Rate
89%(8/9)
Active Trials
27(69%)
Results Posted
88%(7 trials)
Terminated
1(3%)

Phase Distribution

Ph phase_2
12
31%
Ph phase_1
18
46%
Ph phase_3
9
23%

Phase Distribution

18

Early Stage

12

Mid Stage

9

Late Stage

Phase Distribution39 total trials
Phase 1Safety & dosage
18(46.2%)
Phase 2Efficacy & side effects
12(30.8%)
Phase 3Large-scale testing
9(23.1%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

80.0%

8 of 10 finished

Non-Completion Rate

20.0%

2 ended early

Currently Active

27

trials recruiting

Total Trials

39

all time

Status Distribution
Active(29)
Completed(8)
Terminated(2)

Detailed Status

Active, not recruiting14
Recruiting13
Completed8
Not yet recruiting2
Withdrawn1
Terminated1

Development Timeline

Analytics

Development Status

Total Trials
39
Active
27
Success Rate
88.9%
Most Advanced
Phase 3

Trials by Phase

Phase 118 (46.2%)
Phase 212 (30.8%)
Phase 39 (23.1%)

Trials by Status

withdrawn13%
active_not_recruiting1436%
completed821%
not_yet_recruiting25%
terminated13%
recruiting1333%

Recent Activity

Clinical Trials (39)

Showing 20 of 39 trialsScroll for more
NCT02523014Phase 2

Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

Recruiting
NCT02465060Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

Active Not Recruiting
NCT03660826Phase 2

Testing the Combination of Olaparib and Durvalumab, Cediranib and Durvalumab, Olaparib and Capivasertib, and Cediranib Alone in Recurrent or Refractory Endometrial Cancer Following the Earlier Phase of the Study That Tested Olaparib and Cediranib in Comparison to Cediranib Alone, and Olaparib Alone

Active Not Recruiting
NCT04493853Phase 3

Capivasertib+Abiraterone as Treatment for Patients With Metastatic Hormone-sensitive Prostate Cancer and PTEN Deficiency

Active Not Recruiting
NCT07343960Phase 1

A Phase I Study to Investigate the Pharmacokinetics and Safety of Capivasertib in Participants With Moderate Hepatic Impairment

Recruiting
NCT02208375Phase 1

mTORC1/2 Inhibitor AZD2014 or the Oral AKT Inhibitor AZD5363 for Recurrent Endometrial and Ovarian

Active Not Recruiting
NCT07287917Phase 1

Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors

Recruiting
NCT06982521Phase 3

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

Recruiting
NCT07793578Phase 1

Immunotherapy Plus Capivasertib for Metastatic Bladder Cancer

Not Yet Recruiting
NCT05593497Phase 2

A Single-Arm Phase II Study of Neoadjuvant Intensified Androgen Deprivation (Leuprolide and Abiraterone Acetate) in Combination With AKT Inhibition (Capivasertib) for High-Risk Localized Prostate Cancer With PTEN Loss

Recruiting
NCT04862663Phase 3

Capivasertib + CDK4/6i + Fulvestrant for Advanced/Metastatic HR+/HER2- Breast Cancer (CAPItello-292)

Active Not Recruiting
NCT06635447Phase 3

Capivasertib+Fulvestrant asTreatment for Locally Advanced(Inoperable) or Metastatic HR+/HER2- Breast Cancer in Chinese Patients

Active Not Recruiting
NCT04812366Phase 2

Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer

Recruiting
NCT07281833Phase 3

Phase III Study to Evaluate the Safety, Efficacy, and Impact on Quality of Life of Capivasertib Alongside Standard-of-care Endocrine Treatment in Patients With HR+/HER2- Advanced Breast Cancer and Progression on Prior Endocrine-based Treatment

Recruiting
NCT03742102Phase 1

A Study of Novel Anti-cancer Agents in Patients With Metastatic Triple Negative Breast Cancer

Active Not Recruiting
NCT04556773Phase 1

A Phase 1b Study of T-DXd Combinations in HER2-low Advanced or Metastatic Breast Cancer

Active Not Recruiting
NCT07426822Phase 2

Rash & Diarrhea Prophylaxis With Capivasertib

Recruiting
NCT07241065Phase 1

A Study to Investigate the Effect of Capivasertib on the Pharmacokinetics of Oral Dextromethorphan (CYP2D6 Substrate) in Healthy Participants

Completed
NCT02813135Phase 1

European Proof-of-Concept Therapeutic Stratification Trial of Molecular Anomalies in Relapsed or Refractory Tumors

Recruiting
NCT06764186Phase 3

A Phase IIIB Study to Evaluate the Use of Capivasertib in Combination With Fulvestrant in Patients With Advanced Breast Cancer Who Have Relapsed/Progressed on ET and CDK4/6 Inhibitor Reflecting Real World Clinical Practice in Spain

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
39