Success Metrics

Clinical Success Rate
87.5%

Based on 7 completed trials

Completion Rate
88%(7/8)
Active Trials
26(70%)
Results Posted
86%(6 trials)
Terminated
1(3%)

Phase Distribution

Ph phase_2
11
30%
Ph phase_1
17
46%
Ph phase_3
9
24%

Phase Distribution

17

Early Stage

11

Mid Stage

9

Late Stage

Phase Distribution37 total trials
Phase 1Safety & dosage
17(45.9%)
Phase 2Efficacy & side effects
11(29.7%)
Phase 3Large-scale testing
9(24.3%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

77.8%

7 of 9 finished

Non-Completion Rate

22.2%

2 ended early

Currently Active

26

trials recruiting

Total Trials

37

all time

Status Distribution
Active(28)
Completed(7)
Terminated(2)

Detailed Status

Recruiting13
Active, not recruiting13
Completed7
Not yet recruiting2
Terminated1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
37
Active
26
Success Rate
87.5%
Most Advanced
Phase 3

Trials by Phase

Phase 117 (45.9%)
Phase 211 (29.7%)
Phase 39 (24.3%)

Trials by Status

completed719%
recruiting1335%
terminated13%
withdrawn13%
active_not_recruiting1335%
not_yet_recruiting25%

Recent Activity

Clinical Trials (37)

Showing 20 of 37 trialsScroll for more
NCT05563220Phase 1

Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Participants With Metastatic Breast Cancer

Active Not Recruiting
NCT02208375Phase 1

mTORC1/2 Inhibitor AZD2014 or the Oral AKT Inhibitor AZD5363 for Recurrent Endometrial and Ovarian

Active Not Recruiting
NCT06982521Phase 3

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

Recruiting
NCT02465060Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

Active Not Recruiting
NCT02523014Phase 2

Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

Recruiting
NCT03660826Phase 2

Testing the Combination of Olaparib and Durvalumab, Cediranib and Durvalumab, Olaparib and Capivasertib, and Cediranib Alone in Recurrent or Refractory Endometrial Cancer Following the Earlier Phase of the Study That Tested Olaparib and Cediranib in Comparison to Cediranib Alone, and Olaparib Alone

Active Not Recruiting
NCT05039801Phase 1

IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors

Recruiting
NCT04862663Phase 3

Capivasertib + CDK4/6i + Fulvestrant for Advanced/Metastatic HR+/HER2- Breast Cancer (CAPItello-292)

Recruiting
NCT07343960Phase 1

A Phase I Study to Investigate the Pharmacokinetics and Safety of Capivasertib in Participants With Moderate Hepatic Impairment

Recruiting
NCT07287917Phase 1

Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors

Recruiting
NCT04439123Phase 2

Testing AZD5363 as a Potential Targeted Treatment in Cancers With AKT Genetic Changes (MATCH-Subprotocol Y)

Active Not Recruiting
NCT04493853Phase 3

Capivasertib+Abiraterone as Treatment for Patients With Metastatic Hormone-sensitive Prostate Cancer and PTEN Deficiency

Active Not Recruiting
NCT04305496Phase 3

Capivasertib+Fulvestrant vs Placebo+Fulvestrant as Treatment for Locally Advanced (Inoperable) or Metastatic HR+/HER2- Breast Cancer

Active Not Recruiting
NCT03742102Phase 1

A Study of Novel Anti-cancer Agents in Patients With Metastatic Triple Negative Breast Cancer

Active Not Recruiting
NCT07241065Phase 1

A Study to Investigate the Effect of Capivasertib on the Pharmacokinetics of Oral Dextromethorphan (CYP2D6 Substrate) in Healthy Participants

Recruiting
NCT06764186Phase 3

A Phase IIIB Study to Evaluate the Use of Capivasertib in Combination With Fulvestrant in Patients With Advanced Breast Cancer Who Have Relapsed/Progressed on ET and CDK4/6 Inhibitor Reflecting Real World Clinical Practice in Spain

Active Not Recruiting
NCT06635447Phase 3

Capivasertib+Fulvestrant asTreatment for Locally Advanced(Inoperable) or Metastatic HR+/HER2- Breast Cancer in Chinese Patients

Active Not Recruiting
NCT05593497Phase 2

A Single-Arm Phase II Study of Neoadjuvant Intensified Androgen Deprivation (Leuprolide and Abiraterone Acetate) in Combination With AKT Inhibition (Capivasertib) for High-Risk Localized Prostate Cancer With PTEN Loss

Recruiting
NCT07294677Phase 1

CApivasertib, Venetoclax And Low-intensity chemotheRapY for Adults With ALL/LBL

Recruiting
NCT07088913Phase 1

A Study to Investigate the Effect of Capivasertib on the Pharmacokinetics of Oral Rosuvastatin in Healthy Participants

Completed

Drug Details

Intervention Type
DRUG
Total Trials
37