Success Metrics

Clinical Success Rate
73.6%

Based on 67 completed trials

Completion Rate
74%(67/91)
Active Trials
74(40%)
Results Posted
94%(63 trials)
Terminated
24(13%)

Phase Distribution

Ph phase_1
46
25%
Ph phase_3
22
12%
Ph not_applicable
1
1%
Ph early_phase_1
1
1%
Ph phase_4
2
1%
Ph phase_2
107
58%

Phase Distribution

47

Early Stage

107

Mid Stage

24

Late Stage

Phase Distribution179 total trials
Early Phase 1First-in-human
1(0.6%)
Phase 1Safety & dosage
46(25.7%)
Phase 2Efficacy & side effects
107(59.8%)
Phase 3Large-scale testing
22(12.3%)
Phase 4Post-market surveillance
2(1.1%)
N/ANon-phased studies
1(0.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

70.5%

67 of 95 finished

Non-Completion Rate

29.5%

28 ended early

Currently Active

74

trials recruiting

Total Trials

186

all time

Status Distribution
Active(81)
Completed(67)
Terminated(28)
Other(10)

Detailed Status

Completed67
Recruiting40
Active, not recruiting34
Terminated24
unknown9
Not yet recruiting7

Development Timeline

Analytics

Development Status

Total Trials
186
Active
74
Success Rate
73.6%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (0.6%)
Phase 146 (25.7%)
Phase 2107 (59.8%)
Phase 322 (12.3%)
Phase 42 (1.1%)
N/A1 (0.6%)

Trials by Status

recruiting4022%
unknown95%
withdrawn42%
not_yet_recruiting74%
suspended11%
terminated2413%
active_not_recruiting3418%
completed6736%

Recent Activity

Clinical Trials (186)

Showing 20 of 186 trialsScroll for more
NCT03816345Phase 1

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

Recruiting
NCT03945773Phase 2

Study of Cabozantinib as 2nd Line Treatment in Subjects With Locally Advanced or Metastatic Renal Cell Carcinoma (RCC) With a Clear-Cell Component Who Progressed After 1st Line Treatment With Checkpoint Inhibitors

Completed
NCT07011719Phase 3

Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma

Recruiting
NCT04205799Phase 2

Cabozantinib for Advanced or Metastatic Cervical Carcinoma After Platinum Treatment Failure

Completed
NCT07293351Phase 1

A Study to Evaluate the Safety, Tolerability, and Efficacy of Pumitamig Alone or in Combination With Ipilimumab or Cabozantinib in Participants With Advanced Renal Cell Carcinoma (RCC) (ROSETTA RCC-208)

Recruiting
NCT05663710Phase 1

Phase 1b/2 Study of Combination 177Lu Girentuximab Plus Cabozantinib and Nivolumab in Treatment naïve Patients With Advanced Clear Cell RCC

Recruiting
NCT03793166Phase 3

Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer, The PDIGREE Study

Active Not Recruiting
NCT03899155Phase 2

Pan Tumor Rollover Study

Recruiting
NCT05188118Early Phase 1

Rapid Sequencing of Approved Therapies in Patients With Metastatic or Unresectable Clear Cell Renal Cell Carcinoma

Completed
NCT05536141Phase 1

A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors

Recruiting
NCT05263050Phase 2

Trial of an Alternative Cabozantinib Dosing Schedule in Metastatic Renal Cell Carcinoma and Neuroendocrine Tumors

Recruiting
NCT06900595Phase 2

Testing the Addition of an Anti-Cancer Drug, Cabozantinib to the Immunotherapy Drug Cemiplimab (REGN2810), in Adolescents and Adults With Advanced Adrenocortical Cancer

Recruiting
NCT05773274Phase 2

Comparing Retreatment of 177Lu-DOTATATE PRRT Versus the Usual Treatment in Patients With Metastatic Unresectable Gastroenteropancreatic Neuroendocrine Tumors, NET RETREAT Trial

Recruiting
NCT07227402Phase 3

A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033)

Recruiting
NCT07405164Phase 3

Extension Study for Participants in Studies That Include Belzutifan (MK-6482-043/LITESPARK-043)

Recruiting
NCT03768063Phase 3

A Study in Patients Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study

Active Not Recruiting
NCT04413123Phase 2

Cabozantinib In Combo With NIVO + IPI In Advanced NCCRCC

Active Not Recruiting
NCT02867592Phase 2

Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors

Active Not Recruiting
NCT04164979Phase 2

Ph II Study of Cabozantinib With Pembrolizumab in Metastatic Gastric and Gastroesophageal Adenocarcinoma

Completed
NCT03541902Phase 2

Cabozantinib or Sunitinib Malate in Treating Participants With Metastatic Variant Histology Renal Cell Carcinoma

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
186