Success Metrics

Clinical Success Rate
73.0%

Based on 65 completed trials

Completion Rate
73%(65/89)
Active Trials
76(41%)
Results Posted
95%(62 trials)
Terminated
24(13%)

Phase Distribution

Ph phase_4
2
1%
Ph phase_1
46
25%
Ph not_applicable
1
1%
Ph early_phase_1
1
1%
Ph phase_2
107
58%
Ph phase_3
22
12%

Phase Distribution

47

Early Stage

107

Mid Stage

24

Late Stage

Phase Distribution179 total trials
Early Phase 1First-in-human
1(0.6%)
Phase 1Safety & dosage
46(25.7%)
Phase 2Efficacy & side effects
107(59.8%)
Phase 3Large-scale testing
22(12.3%)
Phase 4Post-market surveillance
2(1.1%)
N/ANon-phased studies
1(0.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

69.9%

65 of 93 finished

Non-Completion Rate

30.1%

28 ended early

Currently Active

76

trials recruiting

Total Trials

186

all time

Status Distribution
Active(83)
Completed(65)
Terminated(28)
Other(10)

Detailed Status

Completed65
Recruiting43
Active, not recruiting33
Terminated24
unknown9
Not yet recruiting7

Development Timeline

Analytics

Development Status

Total Trials
186
Active
76
Success Rate
73.0%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (0.6%)
Phase 146 (25.7%)
Phase 2107 (59.8%)
Phase 322 (12.3%)
Phase 42 (1.1%)
N/A1 (0.6%)

Trials by Status

not_yet_recruiting74%
recruiting4323%
withdrawn42%
completed6535%
terminated2413%
unknown95%
active_not_recruiting3318%
suspended11%

Recent Activity

Clinical Trials (186)

Showing 20 of 186 trialsScroll for more
NCT07227402Phase 3

A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033)

Recruiting
NCT07405164Phase 3

Extension Study for Participants in Studies That Include Belzutifan (MK-6482-043/LITESPARK-043)

Recruiting
NCT05039281Phase 1

Atezolizumab and Cabozantinib for the Treatment of Recurrent Glioblastoma

Recruiting
NCT03816345Phase 1

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

Recruiting
NCT07383441Phase 3

Adding Biotherapy or Placebo to Standard Treatment for Advanced Kidney Cancer

Recruiting
NCT02867592Phase 2

Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors

Active Not Recruiting
NCT06900595Phase 2

Testing the Addition of an Anti-Cancer Drug, Cabozantinib to the Immunotherapy Drug Cemiplimab (REGN2810), in Adolescents and Adults With Advanced Adrenocortical Cancer

Recruiting
NCT05613894Phase 1

Dose-Escalation Study of Cabozantinib in Combination With Lutetium-177 (177Lu)-PSMA-617 in Patients With Metastatic Castration-Resistant Prostate Cancer

Suspended
NCT06026410Phase 1

KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

Recruiting
NCT04322955Phase 2

CYTO Reductive Surgery in Kidney Cancer Plus Immunotherapy and Targeted Kinase Inhibition

Active Not Recruiting
NCT03899155Phase 2

Pan Tumor Rollover Study

Recruiting
NCT05773274Phase 2

Comparing Retreatment of 177Lu-DOTATATE PRRT Versus the Usual Treatment in Patients With Metastatic Unresectable Gastroenteropancreatic Neuroendocrine Tumors, NET RETREAT Trial

Recruiting
NCT07620574Phase 3

Long-Term Extension Study for Participants Previously Enrolled in an Exelixis-Sponsored Study

Not Yet Recruiting
NCT07011719Phase 3

Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma

Recruiting
NCT05536141Phase 1

A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors

Recruiting
NCT03793166Phase 3

Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer, The PDIGREE Study

Active Not Recruiting
NCT03611595Phase 1

Cabozantinib in Combination With 13-cis-Retinoic Acid in Children With Relapsed or Refractory Solid Tumors

Completed
NCT07293351Phase 1

A Study to Evaluate the Safety, Tolerability, and Efficacy of Pumitamig Alone or in Combination With Ipilimumab or Cabozantinib in Participants With Advanced Renal Cell Carcinoma (RCC) (ROSETTA RCC-208)

Recruiting
NCT05263050Phase 2

Trial of an Alternative Cabozantinib Dosing Schedule in Metastatic Renal Cell Carcinoma and Neuroendocrine Tumors

Recruiting
NCT06475989Phase 3

Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
186