Success Metrics

Clinical Success Rate
77.3%

Based on 218 completed trials

Completion Rate
77%(218/282)
Active Trials
59(14%)
Results Posted
66%(143 trials)
Terminated
64(15%)

Phase Distribution

Ph phase_2
229
54%
Ph not_applicable
29
7%
Ph phase_3
37
9%
Ph early_phase_1
5
1%
Ph phase_1
115
27%
Ph phase_4
4
1%

Phase Distribution

120

Early Stage

229

Mid Stage

41

Late Stage

Phase Distribution419 total trials
Early Phase 1First-in-human
5(1.2%)
Phase 1Safety & dosage
115(27.4%)
Phase 2Efficacy & side effects
229(54.7%)
Phase 3Large-scale testing
37(8.8%)
Phase 4Post-market surveillance
4(1.0%)
N/ANon-phased studies
29(6.9%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

71.0%

218 of 307 finished

Non-Completion Rate

29.0%

89 ended early

Currently Active

59

trials recruiting

Total Trials

422

all time

Status Distribution
Active(67)
Completed(218)
Terminated(89)
Other(48)

Detailed Status

Completed218
Terminated64
unknown46
Recruiting35
Withdrawn25
Active, not recruiting24

Development Timeline

Analytics

Development Status

Total Trials
422
Active
59
Success Rate
77.3%
Most Advanced
Phase 4

Trials by Phase

Early Phase 15 (1.2%)
Phase 1115 (27.4%)
Phase 2229 (54.7%)
Phase 337 (8.8%)
Phase 44 (1.0%)
N/A29 (6.9%)

Trials by Status

terminated6415%
unknown4611%
active_not_recruiting246%
enrolling_by_invitation20%
suspended20%
completed21852%
recruiting358%
withdrawn256%
not_yet_recruiting61%

Recent Activity

Clinical Trials (422)

Showing 20 of 422 trialsScroll for more
NCT02629120Phase 1

High Dose Peripheral Blood Stem Cell Transplantation With Post Transplant Cyclophosphamide for Patients With Chronic Granulomatous Disease

Active Not Recruiting
NCT07524530Phase 2

Stem Cell Transplantation for Participants With Germline RUNX1 Associated Blood Cancers

Not Yet Recruiting
NCT06325709Phase 1

Base Editing for Mutation Repair in Hematopoietic Stem & Progenitor Cells for X-Linked Chronic Granulomatous Disease

Recruiting
NCT02861417Phase 2

Busulfan, Fludarabine Phosphate, and Post-Transplant Cyclophosphamide in Treating Patients With Blood Cancer Undergoing Donor Stem Cell Transplant

Active Not Recruiting
NCT03619551Phase 2

Conditioning SCID Infants Diagnosed Early

Active Not Recruiting
NCT05564390Phase 2

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Recruiting
NCT03910452Early Phase 1

Haploidentical Transplant for People With Chronic Granulomatous Disease (CGD) Using Alemtuzumab, Busulfan and TBI With Post-Transplant Cyclophosphamide

Active Not Recruiting
NCT06959771Phase 1

Base Editing Hematopoietic Stem Cell and T Cell Gene Therapy for CD40L-HyperIgM Syndrome: Single Patient Study

Recruiting
NCT06207799Phase 2

Pre-transplant Purging and Post-transplant MRD-guided Maintenance Therapy With Elranatamab in Patients With High-risk Multiple Myeloma

Recruiting
NCT05327023Phase 1

Donor Lymphocyte Infusion After Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic Malignancies

Recruiting
NCT07737769Phase 1

Arsenic Trioxide to Prevent Relapse in Patients Undergoing Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia or Myelodysplastic Syndrome

Not Yet Recruiting
NCT02727803Phase 2

Personalized NK Cell Therapy in CBT

Recruiting
NCT05457556Phase 3

Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome

Active Not Recruiting
NCT03259503Phase 1

Olaparib and High-Dose Chemotherapy in Treating Patients With Relapsed or Refractory Lymphomas Undergoing Stem Cell Transplant

Completed
NCT03779854Phase 2

Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

Recruiting
NCT01306019Phase 1

Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)

Recruiting
NCT07113743Phase 1

Part B- G1X-CGD (Lentiviral Vector Transduced CD34+ Cells) in Patients With X-Linked Chronic Granulomatous Disease

Enrolling By Invitation
NCT06079879Phase 3

A Study of Bomedemstat (IMG-7289/MK-3543) Compared to Best Available Therapy (BAT) in Participants With Essential Thrombocythemia and an Inadequate Response or Intolerance of Hydroxyurea (MK-3543-006)

Active Not Recruiting
NCT05027945Phase 2

A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Subjects With VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) Syndrome

Recruiting
NCT01666080Not Applicable

Second or Greater Allogeneic Hematopoietic Stem Cell Transplant Using Reduced Intensity Conditioning (RIC)

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
422