Success Metrics

Clinical Success Rate
100.0%

Based on 12 completed trials

Completion Rate
100%(12/12)
Active Trials
0(0%)
Results Posted
58%(7 trials)

Phase Distribution

Ph phase_2
4
29%
Ph early_phase_1
1
7%
Ph phase_1
1
7%
Ph phase_3
6
43%

Phase Distribution

2

Early Stage

4

Mid Stage

6

Late Stage

Phase Distribution12 total trials
Early Phase 1First-in-human
1(8.3%)
Phase 1Safety & dosage
1(8.3%)
Phase 2Efficacy & side effects
4(33.3%)
Phase 3Large-scale testing
6(50.0%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

100.0%

12 of 12 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

0

trials recruiting

Total Trials

14

all time

Status Distribution
Completed(12)
Other(2)

Detailed Status

Completed12
unknown2

Development Timeline

Analytics

Development Status

Total Trials
14
Active
0
Success Rate
100.0%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (8.3%)
Phase 11 (8.3%)
Phase 24 (33.3%)
Phase 36 (50.0%)

Trials by Status

unknown214%
completed1286%

Recent Activity

Clinical Trials (14)

Showing 14 of 14 trials
NCT05509595Phase 2

Burosumab for Fibroblast Growth Factor-23 Mediated Hypophosphatemia in Fibrous Dysplasia

Completed
NCT03775187

Expanded Access to Burosumab

Unknown
NCT04188964Phase 1

Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of Burosumab in Patients Less Than 1 Year of Age

Completed
NCT05181839

A Study to Describe the Lived Experience of XLH for Adolescents at End of Skeletal Growth

Completed
NCT02915705Phase 3

Efficacy and Safety of Burosumab Versus Oral Phosphate and Active Vitamin D Treatment in Pediatric Patients With XLH

Completed
NCT02537431Phase 3

Open Label Study of KRN23 on Osteomalacia in Adults With X-linked Hypophosphatemia (XLH)

Completed
NCT02526160Phase 3

Study of KRN23 in Adults With X-linked Hypophosphatemia (XLH)

Completed
NCT02163577Phase 2

Study of KRN23 (Burosumab), a Recombinant Fully Human Monoclonal Antibody Against Fibroblast Growth Factor 23 (FGF23), in Pediatric Subjects With X-linked Hypophosphatemia (XLH)

Completed
NCT02304367Phase 2

Study of Burosumab (KRN23) in Adults With Tumor-Induced Osteomalacia (TIO) or Epidermal Nevus Syndrome (ENS)

Completed
NCT02750618Phase 2

Study of the Safety, Pharmacodynamics (PD) and Efficacy of KRN23 in Children From 1 to 4 Years Old With X-linked Hypophosphatemia (XLH)

Completed
NCT04695860Phase 3

Anti-FGF23 (Burosumab) in Adult Patients With XLH

Completed
NCT03920072Phase 3

Study of the Anti-FGF23 Antibody, Burosumab, in Adults With XLH

Completed
NCT03993821Early Phase 1

Burosumab for CSHS

Unknown
NCT03581591Phase 3

Open Label Trial Assessing Safety and Efficacy of Burosumab (KRN23), in a Patient With ENS and Hypophosphatemic Rickets

Completed

All 14 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
14