Success Metrics

Clinical Success Rate
80.0%

Based on 8 completed trials

Completion Rate
80%(8/10)
Active Trials
5(28%)
Results Posted
38%(3 trials)
Terminated
2(11%)

Phase Distribution

Ph phase_2
8
44%
Ph phase_3
4
22%
Ph phase_4
1
6%
Ph phase_1
4
22%
Ph not_applicable
1
6%

Phase Distribution

4

Early Stage

8

Mid Stage

5

Late Stage

Phase Distribution18 total trials
Phase 1Safety & dosage
4(22.2%)
Phase 2Efficacy & side effects
8(44.4%)
Phase 3Large-scale testing
4(22.2%)
Phase 4Post-market surveillance
1(5.6%)
N/ANon-phased studies
1(5.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

66.7%

8 of 12 finished

Non-Completion Rate

33.3%

4 ended early

Currently Active

5

trials recruiting

Total Trials

18

all time

Status Distribution
Active(6)
Completed(8)
Terminated(4)

Detailed Status

Completed8
Recruiting4
Terminated2
Withdrawn2
Active, not recruiting1
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
18
Active
5
Success Rate
80.0%
Most Advanced
Phase 4

Trials by Phase

Phase 14 (22.2%)
Phase 28 (44.4%)
Phase 34 (22.2%)
Phase 41 (5.6%)
N/A1 (5.6%)

Trials by Status

terminated211%
withdrawn211%
active_not_recruiting16%
not_yet_recruiting16%
completed844%
recruiting422%

Recent Activity

5 active trials
Showing 5 of 18
active_not_recruitingphase_1

Delivering a Diuretic Into the Liver Artery Followed by Plugging up the Artery to Starve Out Liver Cancer Cells

NCT03107416
not_yet_recruitingphase_3

Bumetanide vs. Furosemide in Cirrhosis

NCT06941415
completedphase_2

Efficacy of Bumetanide in Children With Autism Spectrum Disorder Guided by Peripheral Blood Biomarkers and Machine Learning Models

NCT07005414
completedphase_2

A Study of Ultra High Dose Diuretics to Treat Heart Failure

NCT06036914
recruitingphase_2

Bumetanide in Patients With Alzheimer's Disease

NCT06052163
View all 18 trials

Clinical Trials (18)

Showing 18 of 18 trials
NCT03107416Phase 1

Delivering a Diuretic Into the Liver Artery Followed by Plugging up the Artery to Starve Out Liver Cancer Cells

Active Not Recruiting
NCT06941415Phase 3

Bumetanide vs. Furosemide in Cirrhosis

Not Yet Recruiting
NCT07005414Phase 2

Efficacy of Bumetanide in Children With Autism Spectrum Disorder Guided by Peripheral Blood Biomarkers and Machine Learning Models

Completed
NCT06036914Phase 2

A Study of Ultra High Dose Diuretics to Treat Heart Failure

Completed
NCT06052163Phase 2

Bumetanide in Patients With Alzheimer's Disease

Recruiting
NCT06465823Phase 2

Efficacy of Bumetanide to Improve Cognitive Functions in Down Syndrome

Recruiting
NCT06218199Phase 4

Diuretics vs. Afterload Reduction for Treatment of HeartLogic Alerts

Recruiting
NCT02593526Not Applicable

Diuretic/Cool Dialysate Trial

Terminated
NCT02947880Phase 2

Evaluation of the Efficiency of Treatment by BUMETANIDE on Autistic Children With a Known Ethiology

Withdrawn
NCT03156153Phase 2

A Study of Bumetanide for the Treatment of Autism Spectrum Disorders

Completed
NCT04766177Phase 3

Role of Bumetanide in Treatment of Autism

Recruiting
NCT00830531Phase 1

Pilot Study of Bumetanide for Newborn Seizures

Completed
NCT03923933Phase 2

Chlortalidone and Bumetanide in Advanced Chronic Kidney Disease: HEBE-CKD Trial

Completed
NCT02582476Phase 2

Bumetanide in Hypokalaemic Periodic Paralysis

Terminated
NCT00930865Phase 1

Study to Evaluate the Potential Pharmacokinetic Interaction and Pharmacodynamic Effects on Renal Parameters of Bumetanide (1mg) and Dapagliflozin (10 mg) When Co-administered in Healthy Subjects

Completed
NCT01434225Phase 1

NEMO1:NEonatal Seizure Using Medication Off-patent

Completed
NCT00372762Phase 3

Bumetanide Versus Furosemide in Heart Failure

Withdrawn
NCT01078714Phase 3

Efficiency of Bumetanide in Autistic Children

Completed

All 18 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
18