Success Metrics

Clinical Success Rate
80.0%

Based on 8 completed trials

Completion Rate
80%(8/10)
Active Trials
6(33%)
Results Posted
38%(3 trials)
Terminated
2(11%)

Phase Distribution

Ph not_applicable
1
6%
Ph phase_4
1
6%
Ph phase_1
4
22%
Ph phase_3
4
22%
Ph phase_2
8
44%

Phase Distribution

4

Early Stage

8

Mid Stage

5

Late Stage

Phase Distribution18 total trials
Phase 1Safety & dosage
4(22.2%)
Phase 2Efficacy & side effects
8(44.4%)
Phase 3Large-scale testing
4(22.2%)
Phase 4Post-market surveillance
1(5.6%)
N/ANon-phased studies
1(5.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

66.7%

8 of 12 finished

Non-Completion Rate

33.3%

4 ended early

Currently Active

6

trials recruiting

Total Trials

18

all time

Status Distribution
Active(6)
Completed(8)
Terminated(4)

Detailed Status

Completed8
Recruiting5
Withdrawn2
Terminated2
Active, not recruiting1

Development Timeline

Analytics

Development Status

Total Trials
18
Active
6
Success Rate
80.0%
Most Advanced
Phase 4

Trials by Phase

Phase 14 (22.2%)
Phase 28 (44.4%)
Phase 34 (22.2%)
Phase 41 (5.6%)
N/A1 (5.6%)

Trials by Status

completed844%
recruiting528%
withdrawn211%
terminated211%
active_not_recruiting16%

Recent Activity

6 active trials
Showing 5 of 18
recruitingphase_3

Bumetanide vs. Furosemide in Cirrhosis

NCT06941415
withdrawnphase_2

Evaluation of the Efficiency of Treatment by BUMETANIDE on Autistic Children With a Known Ethiology

NCT02947880
active_not_recruitingphase_1

Delivering a Diuretic Into the Liver Artery Followed by Plugging up the Artery to Starve Out Liver Cancer Cells

NCT03107416
completedphase_2

Efficacy of Bumetanide in Children With Autism Spectrum Disorder Guided by Peripheral Blood Biomarkers and Machine Learning Models

NCT07005414
completedphase_2

A Study of Ultra High Dose Diuretics to Treat Heart Failure

NCT06036914
View all 18 trials

Clinical Trials (18)

Showing 18 of 18 trials
NCT06941415Phase 3

Bumetanide vs. Furosemide in Cirrhosis

Recruiting
NCT02947880Phase 2

Evaluation of the Efficiency of Treatment by BUMETANIDE on Autistic Children With a Known Ethiology

Withdrawn
NCT03107416Phase 1

Delivering a Diuretic Into the Liver Artery Followed by Plugging up the Artery to Starve Out Liver Cancer Cells

Active Not Recruiting
NCT07005414Phase 2

Efficacy of Bumetanide in Children With Autism Spectrum Disorder Guided by Peripheral Blood Biomarkers and Machine Learning Models

Completed
NCT06036914Phase 2

A Study of Ultra High Dose Diuretics to Treat Heart Failure

Completed
NCT06052163Phase 2

Bumetanide in Patients With Alzheimer's Disease

Recruiting
NCT06465823Phase 2

Efficacy of Bumetanide to Improve Cognitive Functions in Down Syndrome

Recruiting
NCT06218199Phase 4

Diuretics vs. Afterload Reduction for Treatment of HeartLogic Alerts

Recruiting
NCT02593526Not Applicable

Diuretic/Cool Dialysate Trial

Terminated
NCT03156153Phase 2

A Study of Bumetanide for the Treatment of Autism Spectrum Disorders

Completed
NCT04766177Phase 3

Role of Bumetanide in Treatment of Autism

Recruiting
NCT00830531Phase 1

Pilot Study of Bumetanide for Newborn Seizures

Completed
NCT03923933Phase 2

Chlortalidone and Bumetanide in Advanced Chronic Kidney Disease: HEBE-CKD Trial

Completed
NCT02582476Phase 2

Bumetanide in Hypokalaemic Periodic Paralysis

Terminated
NCT00930865Phase 1

Study to Evaluate the Potential Pharmacokinetic Interaction and Pharmacodynamic Effects on Renal Parameters of Bumetanide (1mg) and Dapagliflozin (10 mg) When Co-administered in Healthy Subjects

Completed
NCT01434225Phase 1

NEMO1:NEonatal Seizure Using Medication Off-patent

Completed
NCT00372762Phase 3

Bumetanide Versus Furosemide in Heart Failure

Withdrawn
NCT01078714Phase 3

Efficiency of Bumetanide in Autistic Children

Completed

All 18 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
18