Success Metrics

Clinical Success Rate
58.3%

Based on 7 completed trials

Completion Rate
58%(7/12)
Active Trials
2(11%)
Results Posted
129%(9 trials)
Terminated
5(28%)

Phase Distribution

Ph phase_1
3
17%
Ph phase_2
7
39%
Ph phase_3
6
33%

Phase Distribution

3

Early Stage

7

Mid Stage

6

Late Stage

Phase Distribution16 total trials
Phase 1Safety & dosage
3(18.8%)
Phase 2Efficacy & side effects
7(43.8%)
Phase 3Large-scale testing
6(37.5%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

50.0%

7 of 14 finished

Non-Completion Rate

50.0%

7 ended early

Currently Active

2

trials recruiting

Total Trials

18

all time

Status Distribution
Active(2)
Completed(7)
Terminated(7)
Other(2)

Detailed Status

Completed7
Terminated5
Recruiting2
Withdrawn2
unknown1
Suspended1

Development Timeline

Analytics

Development Status

Total Trials
18
Active
2
Success Rate
58.3%
Most Advanced
Phase 3

Trials by Phase

Phase 13 (18.8%)
Phase 27 (43.8%)
Phase 36 (37.5%)

Trials by Status

completed739%
unknown16%
terminated528%
recruiting211%
suspended16%
withdrawn211%

Recent Activity

Clinical Trials (18)

Showing 18 of 18 trials
NCT07511049Phase 2

Intravenous Brincidofovir as an Antiviral for Treatment of Progressive Multifocal Leukoencephalopathy: A Pilot Study

Recruiting
NCT07387367Phase 3

A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT

Recruiting
NCT06761677Phase 1

A Phase 1b/2 Study of Intravenous Brincidofovir in Patients With Relapsed or Refractory Lymphoma and Relapsed or Refractory Extranodal Natural Killer/T-cell Lymphoma

Suspended
NCT05935917Phase 1

Study Evaluating the Bioequivalence of Brincidofovir Form H and Form II Tablets in Healthy Adults

Completed
NCT05511779Phase 2

Study to Confirm of the Safety and Tolerability of Brincidofovir in Subjects With BK Virus Infection (Viremia) After Kidney Transplantation

Terminated
NCT02596997

Expanded Access Protocol to Provide Brincidofovir for the Treatment of Serious Adenovirus Infection or Disease

Unknown
NCT00793598Phase 1

CMX001 in Post-transplant Patients With BK Virus Viruria

Completed
NCT02087306Phase 3

Study to Assess the Safety and Efficacy of Brincidofovir in Treatment of Early Versus Late Adenovirus Infection

Completed
NCT01143181Phase 3

Study to Assess Brincidofovir Treatment of Serious Diseases or Conditions Caused by Double-stranded DNA Viruses

Completed
NCT03532035Phase 2

Open Label Study of IV Brincidofovir in Adult Transplant Recipients With Adenovirus Viremia

Withdrawn
NCT01241344Phase 2

Phase 2 Study to Evaluate Brincidofovir for the Prevention of Adenovirus Disease

Completed
NCT01769170Phase 3

A Study of the Safety and Efficacy of CMX001 for the Prevention of CMV Infection in CMV-seropositive HCT Recipients

Completed
NCT00942305Phase 2

Study of CMX001 to Prevent/Control Cytomegalovirus Infection in R+ Hematopoietic Stem Cell Transplant Recipients

Completed
NCT02439970Phase 3

A Phase 3 Study of Brincidofovir Versus Valganciclovir for the Prevention of Cytomegalovirus Disease

Terminated
NCT02439957Phase 3

A Phase 3 Study of Brincidofovir Versus Valganciclovir for the Prevention of Cytomegalovirus

Terminated
NCT03339401Phase 2

The AdAPT Trial; Adenovirus After Allogeneic Pediatric Transplantation

Terminated
NCT04268966Phase 2

An Open-Label Study , Safety and Tolerability of Brincidofovir for Post Exposure Prophylaxis of Ebola

Withdrawn
NCT02420080

A Multicenter Study to Obtain Retrospective Data for Subjects Previously Diagnosed With Adenovirus Infection to Serve as Matched Historical Controls for Study CMX001-304

Terminated

All 18 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
18