Success Metrics

Clinical Success Rate
80.0%

Based on 72 completed trials

Completion Rate
80%(72/90)
Active Trials
38(25%)
Results Posted
89%(64 trials)
Terminated
18(12%)

Phase Distribution

Ph not_applicable
3
2%
Ph early_phase_1
1
1%
Ph phase_4
4
3%
Ph phase_1
46
30%
Ph phase_3
14
9%
Ph phase_2
82
54%

Phase Distribution

47

Early Stage

82

Mid Stage

18

Late Stage

Phase Distribution150 total trials
Early Phase 1First-in-human
1(0.7%)
Phase 1Safety & dosage
46(30.7%)
Phase 2Efficacy & side effects
82(54.7%)
Phase 3Large-scale testing
14(9.3%)
Phase 4Post-market surveillance
4(2.7%)
N/ANon-phased studies
3(2.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

69.9%

72 of 103 finished

Non-Completion Rate

30.1%

31 ended early

Currently Active

38

trials recruiting

Total Trials

153

all time

Status Distribution
Active(39)
Completed(72)
Terminated(31)
Other(11)

Detailed Status

Completed72
Active, not recruiting20
Terminated18
Recruiting18
Withdrawn13
unknown9

Development Timeline

Analytics

Development Status

Total Trials
153
Active
38
Success Rate
80.0%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (0.7%)
Phase 146 (30.7%)
Phase 282 (54.7%)
Phase 314 (9.3%)
Phase 44 (2.7%)
N/A3 (2.0%)

Trials by Status

active_not_recruiting2013%
not_yet_recruiting11%
completed7247%
unknown96%
terminated1812%
recruiting1812%
suspended21%
withdrawn138%

Recent Activity

Clinical Trials (153)

Showing 20 of 153 trialsScroll for more
NCT05675410Phase 3

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

Recruiting
NCT03907488Phase 3

Immunotherapy (Nivolumab or Brentuximab Vedotin) Plus Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III-IV Classic Hodgkin Lymphoma

Active Not Recruiting
NCT02166463Phase 3

Brentuximab Vedotin and Combination Chemotherapy in Treating Children and Young Adults With Stage IIB, Stage IIIB, IVA, or IVB Hodgkin Lymphoma

Active Not Recruiting
NCT05149768Phase 2

Open Label Extension Study of Brentuximab Vedotin in Early dcSSc

Completed
NCT01896999Phase 1

Brentuximab Vedotin and Nivolumab With or Without Ipilimumab in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma

Active Not Recruiting
NCT04561206Phase 2

Brentuximab Vedotin and Nivolumab for the Treatment of Patients With Relapsed/Refractory Classical Hodgkin Lymphoma

Recruiting
NCT03233347Phase 2

Doxorubicin, Vinblastine, Dacarbazine, Brentuximab Vedotin, and Nivolumab in Treating Patients With Stage I-II Hodgkin Lymphoma

Active Not Recruiting
NCT03517137Phase 2

Very Early PET-response Adapted Targeted Therapy for Advanced Hodgkin Lymphoma: a Single -Arm Phase II Study

Active Not Recruiting
NCT05039073Phase 2

Brentuximab Vedotin and Nivolumab for the Treatment of Relapsed/Refractory Classic Hodgkin Lymphoma Previously Treated With Brentuximab Vedotin or Checkpoint Inhibitors

Recruiting
NCT03007030Phase 2

Brentuximab Vedotin in Treating Patients With CD30+ Malignant Mesothelioma That Cannot Be Removed by Surgery

Active Not Recruiting
NCT03113500Phase 2

Brentuximab Vedotin and Combination Chemotherapy in Treating Patients With CD30-Positive Peripheral T-cell Lymphoma

Active Not Recruiting
NCT07275216Phase 2

Pembrolizumab in Combination With Chemotherapy for the Treatment of Frail Hodgkin Lymphoma Patients Ineligible for Standard Treatment

Recruiting
NCT05922904Phase 2

PET Adapted Brentuximab Vedotin and Pembrolizumab in Combination With Doxorubicin and Dacarbazine in Classic Hodgkin Lymphoma

Active Not Recruiting
NCT03719105Early Phase 1

Chemoimmunotherapy and Allogeneic Stem Cell Transplant for NK T-cell Leukemia/Lymphoma

Recruiting
NCT04569032Phase 2

A Study of Brentuximab Vedotin and CHP in Frontline Treatment of PTCL With Less Than 10% CD30 Expression

Completed
NCT02227199Phase 1

Brentuximab Vedotin, Ifosfamide, Carboplatin, and Etoposide in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma

Completed
NCT03409432Phase 2

Brentuximab Vedotin and Lenalidomide in Treating Patients With Stage IB-IVB Relapsed or Refractory T-Cell Lymphoma

Completed
NCT05357794Phase 2

Effectiveness of Concurrent Ultra-Low-Dose Total-Skin Electron Beam Therapy and Brentuximab Vedotin Given Quarterly Over 12 Months for Patients With Mycosis Fungoides

Recruiting
NCT03264131Phase 2

BV-CHEP Chemotherapy for Adult T-cell Leukemia or Lymphoma

Completed
NCT04404283Phase 3

Brentuximab Vedotin Plus Lenalidomide and Rituximab for the Treatment of Relapsed/Refractory DLBCL

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
153