Success Metrics

Clinical Success Rate
76.7%

Based on 56 completed trials

Completion Rate
77%(56/73)
Active Trials
25(18%)
Results Posted
46%(26 trials)
Terminated
17(12%)

Phase Distribution

Ph phase_3
29
21%
Ph phase_1
26
19%
Ph phase_4
2
1%
Ph early_phase_1
3
2%
Ph phase_2
37
27%
Ph not_applicable
28
20%

Phase Distribution

29

Early Stage

37

Mid Stage

31

Late Stage

Phase Distribution125 total trials
Early Phase 1First-in-human
3(2.4%)
Phase 1Safety & dosage
26(20.8%)
Phase 2Efficacy & side effects
37(29.6%)
Phase 3Large-scale testing
29(23.2%)
Phase 4Post-market surveillance
2(1.6%)
N/ANon-phased studies
28(22.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

71.8%

56 of 78 finished

Non-Completion Rate

28.2%

22 ended early

Currently Active

25

trials recruiting

Total Trials

137

all time

Status Distribution
Active(31)
Completed(56)
Terminated(22)
Other(28)

Detailed Status

Completed56
unknown28
Terminated17
Recruiting13
Active, not recruiting12
Not yet recruiting6

Development Timeline

Analytics

Development Status

Total Trials
137
Active
25
Success Rate
76.7%
Most Advanced
Phase 4

Trials by Phase

Early Phase 13 (2.4%)
Phase 126 (20.8%)
Phase 237 (29.6%)
Phase 329 (23.2%)
Phase 42 (1.6%)
N/A28 (22.4%)

Trials by Status

terminated1712%
completed5641%
not_yet_recruiting64%
recruiting139%
unknown2820%
withdrawn54%
active_not_recruiting129%

Recent Activity

Clinical Trials (137)

Showing 20 of 137 trialsScroll for more
NCT01655836Phase 1

High-Dose Rate Brachytherapy and Stereotactic Body Radiation Therapy in Treating Patients With Prostate Cancer

Active Not Recruiting
NCT07061977Phase 3

Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

Recruiting
NCT04634877Phase 3

Study of Pembrolizumab (MK-3475) in Combination With Adjuvant Chemotherapy With or Without Radiotherapy in Participants With Newly Diagnosed Endometrial Cancer After Surgery With Curative Intent (MK-3475-B21 / KEYNOTE-B21 / ENGOT-en11 / GOG-3053)

Active Not Recruiting
NCT03543189Phase 1

Combination of Nivolumab Immunotherapy With Radiation Therapy and Androgen Deprivation Therapy

Completed
NCT00525720Phase 2

Brachytherapy for Prostatic Carcinoma Patients

Active Not Recruiting
NCT00769223

Predicting the Risk of Failure in Patients Undergoing Radiation Therapy for Localized Prostate Cancer

Active Not Recruiting
NCT07801027Phase 4

A Trial of Pembrolizumab With Chemotherapy or Chemoradiotherapy in Participants From India With Different Types of Cancer (MK-3475-G44/KEYNOTE-G44)

Not Yet Recruiting
NCT02466971Phase 3

Testing the Addition of a New Anti-Cancer Drug, Triapine, to the Usual Chemotherapy Treatment (Cisplatin) During Radiation Therapy for Advanced-stage Cervical and Vaginal Cancers

Active Not Recruiting
NCT06543576Phase 1

External Beam Radiation Therapy and Brachytherapy With Chemotherapy and Immunotherapy for the Treatment of Stage IVB Cervical Cancer

Recruiting
NCT02595879Phase 1

Triapine With Chemotherapy and Radiation Therapy in Treating Patients With IB2-IVA Cervical or Vaginal Cancer

Active Not Recruiting
NCT04214067Phase 3

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to the Usual Radiation Treatment for Newly Diagnosed Early Stage High Intermediate Risk Endometrial Cancer

Active Not Recruiting
NCT01368588Phase 3

Androgen-Deprivation Therapy and Radiation Therapy in Treating Patients With Prostate Cancer

Active Not Recruiting
NCT03277469Not Applicable

Optimizing Brachytherapy Application and Delivery With MRI Guidance for Gynecologic Cancer

Active Not Recruiting
NCT07530458

Retinoblastoma Consolidation in Egyptians

Not Yet Recruiting
NCT01982786Not Applicable

Feasibility Trial Of Image Guided External Beam Radiotherapy With Or Without High Dose Rate Brachytherapy Boost In Men With Intermediate-Risk Prostate Cancer

Completed
NCT00802711Not Applicable

3-Dimensional Conformal Radiation Therapy or Internal Radiation Therapy After Breast-Conserving Surgery in Treating Women With Stage I or Stage II Breast Cancer

Terminated
NCT05570422Phase 1

A Study to Evaluate the Safety, Tolerability, Preliminary Efficacy of KRC-01

Recruiting
NCT02865837Not Applicable

Effect of Bladder Distension on Dosimetry in Brachytherapy of Cervical Cancer

Completed
NCT03753659Phase 2

IMMULAB - Immunotherapy With Pembrolizumab in Combination With Local Ablation in Hepatocellular Carcinoma (HCC)

Completed
NCT02642809Phase 1

Pembrolizumab With Locally Delivered Radiation Therapy for the Treatment of Metastatic Esophageal Cancers

Completed

Drug Details

Intervention Type
RADIATION
Total Trials
137