Success Metrics

Clinical Success Rate
76.4%

Based on 55 completed trials

Completion Rate
76%(55/72)
Active Trials
25(19%)
Results Posted
45%(25 trials)
Terminated
17(13%)

Phase Distribution

Ph phase_4
1
1%
Ph not_applicable
28
21%
Ph phase_3
28
21%
Ph phase_1
26
19%
Ph early_phase_1
3
2%
Ph phase_2
37
27%

Phase Distribution

29

Early Stage

37

Mid Stage

29

Late Stage

Phase Distribution123 total trials
Early Phase 1First-in-human
3(2.4%)
Phase 1Safety & dosage
26(21.1%)
Phase 2Efficacy & side effects
37(30.1%)
Phase 3Large-scale testing
28(22.8%)
Phase 4Post-market surveillance
1(0.8%)
N/ANon-phased studies
28(22.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

71.4%

55 of 77 finished

Non-Completion Rate

28.6%

22 ended early

Currently Active

25

trials recruiting

Total Trials

135

all time

Status Distribution
Active(30)
Completed(55)
Terminated(22)
Other(28)

Detailed Status

Completed55
unknown28
Terminated17
Recruiting13
Active, not recruiting12
Not yet recruiting5

Development Timeline

Analytics

Development Status

Total Trials
135
Active
25
Success Rate
76.4%
Most Advanced
Phase 4

Trials by Phase

Early Phase 13 (2.4%)
Phase 126 (21.1%)
Phase 237 (30.1%)
Phase 328 (22.8%)
Phase 41 (0.8%)
N/A28 (22.8%)

Trials by Status

not_yet_recruiting54%
active_not_recruiting129%
recruiting1310%
terminated1713%
unknown2821%
withdrawn54%
completed5541%

Recent Activity

Clinical Trials (135)

Showing 20 of 135 trialsScroll for more
NCT07061977Phase 3

Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

Recruiting
NCT02595879Phase 1

Triapine With Chemotherapy and Radiation Therapy in Treating Patients With IB2-IVA Cervical or Vaginal Cancer

Active Not Recruiting
NCT03277469Not Applicable

Optimizing Brachytherapy Application and Delivery With MRI Guidance for Gynecologic Cancer

Active Not Recruiting
NCT07530458

Retinoblastoma Consolidation in Egyptians

Not Yet Recruiting
NCT01982786Not Applicable

Feasibility Trial Of Image Guided External Beam Radiotherapy With Or Without High Dose Rate Brachytherapy Boost In Men With Intermediate-Risk Prostate Cancer

Completed
NCT02466971Phase 3

Testing the Addition of a New Anti-Cancer Drug, Triapine, to the Usual Chemotherapy Treatment (Cisplatin) During Radiation Therapy for Advanced-stage Cervical and Vaginal Cancers

Active Not Recruiting
NCT00802711Not Applicable

3-Dimensional Conformal Radiation Therapy or Internal Radiation Therapy After Breast-Conserving Surgery in Treating Women With Stage I or Stage II Breast Cancer

Terminated
NCT04214067Phase 3

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to the Usual Radiation Treatment for Newly Diagnosed Early Stage High Intermediate Risk Endometrial Cancer

Active Not Recruiting
NCT05570422Phase 1

A Study to Evaluate the Safety, Tolerability, Preliminary Efficacy of KRC-01

Recruiting
NCT03543189Phase 1

Combination of Nivolumab Immunotherapy With Radiation Therapy and Androgen Deprivation Therapy

Active Not Recruiting
NCT02865837Not Applicable

Effect of Bladder Distension on Dosimetry in Brachytherapy of Cervical Cancer

Completed
NCT03753659Phase 2

IMMULAB - Immunotherapy With Pembrolizumab in Combination With Local Ablation in Hepatocellular Carcinoma (HCC)

Completed
NCT02642809Phase 1

Pembrolizumab With Locally Delivered Radiation Therapy for the Treatment of Metastatic Esophageal Cancers

Completed
NCT03315351Not Applicable

Feasibility of Pet-scan at Day 1 of Brachytherapy for Patients With Cervical Cancer

Completed
NCT00525720Phase 2

Brachytherapy for Prostatic Carcinoma Patients

Active Not Recruiting
NCT07182279Phase 1

Neoadjuvant High Dose Rate Brachytherapy Prior to Radical Prostatectomy in Patients With Prostate Cancer

Recruiting
NCT04221945Phase 3

Study of Chemoradiotherapy With or Without Pembrolizumab (MK-3475) For The Treatment of Locally Advanced Cervical Cancer (MK-3475-A18/KEYNOTE-A18/ENGOT-cx11/GOG-3047)

Completed
NCT03955978Phase 1

TSR-042 in Addition to Standard of Care Definitive Radiation for Inoperable Endometrial Cancer

Active Not Recruiting
NCT03738228Phase 1

Atezolizumab Before and/or With Chemoradiotherapy in Immune System Activation in Patients With Node Positive Stage IB2, II, IIIB, or IVA Cervical Cancer

Completed
NCT05100472Phase 2

A Study of Shorter Course Hormone Therapy and Radiation for High-risk Prostate Cancer

Active Not Recruiting

Drug Details

Intervention Type
RADIATION
Total Trials
135