Success Metrics

Clinical Success Rate

100.0%

Based on 7 completed trials

Completion Rate

100%(7/7)

Active Trials

1(9%)

Results Posted

43%(3 trials)

Phase Distribution

Ph phase_2

36%

Ph early_phase_1

Ph not_applicable

27%

Ph phase_1

27%

Phase Distribution

Early Stage

Mid Stage

Late Stage

Phase Distribution11 total trials

Early Phase 1First-in-human

1(9.1%)

Phase 1Safety & dosage

3(27.3%)

Phase 2Efficacy & side effects

4(36.4%)

N/ANon-phased studies

3(27.3%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

87.5%

7 of 8 finished

Non-Completion Rate

12.5%

1 ended early

Currently Active

trials recruiting

Total Trials

all time

Status Distribution

Active(1)

Completed(7)

Terminated(1)

Other(2)

Detailed Status

Completed7

unknown2

Withdrawn1

Recruiting1

Development Timeline

Analytics

Development Status

Total Trials

Active

Success Rate

100.0%

Most Advanced

Phase 2

Trials by Phase

Early Phase 11 (9.1%)

Phase 13 (27.3%)

Phase 24 (36.4%)

N/A3 (27.3%)

Trials by Status

unknown218%

withdrawn19%

recruiting19%

completed764%

Recent Activity

1 active trials

Showing 5 of 11

recruitingphase_1

: Vascular Function in Health and Disease

NCT02966665

completedphase_1

The Effect of Endothelin and L-Arginine on Racial Differences in Vasoconstriction

NCT03679780

completednot_applicable

Clinical Trials (11)

Showing 11 of 11 trials

NCT02966665Phase 1

: Vascular Function in Health and Disease

Recruiting

NCT03679780Phase 1

The Effect of Endothelin and L-Arginine on Racial Differences in Vasoconstriction

Completed

NCT02062346Not Applicable

Endothelin Antagonism in ANCA Vasculitis

Completed

NCT02124824Early Phase 1

Contribution of Endothelin-1 to Exercise Intolerance in Heart Failure

Completed

NCT01119417Phase 1

The Role of Endothelin in the Supine Hypertension of Autonomic Failure

Withdrawn

NCT04907838Not Applicable

Insulin Stimulated Vasodilation in Patients With Type 2 Diabetes

Unknown

NCT00759408Phase 2

The Role of Endothelin in Pulmonary Hypertension

Completed

NCT00586820Phase 2

Role of Endothelin in Microvascular Dysfunction Following PCI for NSTEMI

Completed

NCT00502528Phase 2

Endothelin Receptor Blockade in Acute ST-elevation Myocardial Infarction

Completed

NCT00915070Not Applicable

Role of Endothelin-1 in Optic Nerve Head Blood Flow Regulation During Isometric Exercise in Healthy Humans

Completed

NCT01658410Phase 2

Short-term Endothelin A Receptor Blockade in Patients With On-pump CABG

Unknown

All 11 trials loaded

Drug Details

Intervention Type: DRUG
Total Trials: 11