Success Metrics

Clinical Success Rate
60.0%

Based on 3 completed trials

Completion Rate
60%(3/5)
Active Trials
23(64%)
Results Posted
33%(1 trials)
Terminated
2(6%)

Phase Distribution

Ph phase_1
9
25%
Ph phase_2
23
64%
Ph phase_3
2
6%
Ph early_phase_1
1
3%

Phase Distribution

10

Early Stage

23

Mid Stage

2

Late Stage

Phase Distribution35 total trials
Early Phase 1First-in-human
1(2.9%)
Phase 1Safety & dosage
9(25.7%)
Phase 2Efficacy & side effects
23(65.7%)
Phase 3Large-scale testing
2(5.7%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

50.0%

3 of 6 finished

Non-Completion Rate

50.0%

3 ended early

Currently Active

23

trials recruiting

Total Trials

36

all time

Status Distribution
Active(28)
Completed(3)
Terminated(3)
Other(2)

Detailed Status

Recruiting13
Active, not recruiting10
Not yet recruiting5
Completed3
Terminated2
Suspended1

Development Timeline

Analytics

Development Status

Total Trials
36
Active
23
Success Rate
60.0%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (2.9%)
Phase 19 (25.7%)
Phase 223 (65.7%)
Phase 32 (5.7%)

Trials by Status

suspended13%
recruiting1336%
not_yet_recruiting514%
active_not_recruiting1028%
unknown13%
terminated26%
completed38%
withdrawn13%

Recent Activity

Clinical Trials (36)

Showing 20 of 36 trialsScroll for more
NCT06411691Phase 1

KRAS-Targeted Vaccine Combined With Balstilimab and Botensilimab for Patients With Stage IV MMR-p Colorectal Cancer and Pancreatic Ductal Cancer

Recruiting
NCT07735624Phase 2

RECTIFY-1: Neoadjuvant Botensilimab + Balstilimab in MSS/pMMR Early Rectal Cancer

Not Yet Recruiting
NCT07695311Phase 1

EWSR1 Immunotherapy in Ewing Sarcoma and DSRCT

Not Yet Recruiting
NCT07152821Phase 3

Botensilimab + Balstilimab vs Best Supportive Care as Therapy in Chemo-refractory, Unresectable, Colorectal Adenocarcinoma

Terminated
NCT05632328Phase 2

AGEN1423 and Botensilimab w/ or w/o Chemo in PDAC

Active Not Recruiting
NCT07595874Phase 2

Neoadjuvant Botensilimab and Balstilimab for the Treatment of Advanced Resectable Colorectal Cancer NEST3

Recruiting
NCT06780787Phase 2

FOLFOX, Botensilimab, and Balstilimab for the Treatment of Localized Rectal Cancer Before Surgery

Recruiting
NCT06346197Phase 3

Combination of Immune Checkpoint in Locally Advanced or Metastatic MSI/dMMR Esogastric Adenocarcinomas

Recruiting
NCT06076837Phase 1

The Seven Trial: Exploiting the Unfolded Protein Response

Terminated
NCT06843434Phase 2

A Study of Botensilimab and Balstilimab for Rectal Adenocarcinoma

Recruiting
NCT05630183Phase 2

A Study of Botensilimab in Participants With Metastatic Pancreatic Cancer

Completed
NCT05571293Phase 2

Combination Immunotherapy in Colorectal Cancer

Active Not Recruiting
NCT07516366Phase 2

Testing the Safety and Feasibility of Immunotherapy Drugs, Botensilimab and Balstilimab, Before Surgery for Clear Cell Renal Cell Carcinoma, NEO RoBOT Trial

Not Yet Recruiting
NCT07551596Phase 2

Testing the Combination of Anti-Cancer Drugs, Botensilimab (AGEN1181) and Balstilimab (AGEN2034), After Standard Treatment for Colorectal Cancer, Combat Trial

Not Yet Recruiting
NCT06251973Phase 2

A Study of agenT-797 in Combination With Botensilimab, Balstilimab, Ramucirumab, and Paclitaxel for People With Esophageal, Gastric, or Gastro-esophageal Junction Cancer

Active Not Recruiting
NCT06751524

Expanded Access Program (EAP) Designed to Provide Access to Botensilimab and Balstilimab Before Regulatory Approval

Unknown
NCT06300463Phase 2

Platform Study of Immunotherapy Combinations in Colorectal Cancer Liver Metastases

Recruiting
NCT07128355Early Phase 1

Botensilimab, Balstilimab, and SBRT in Colorectal Cancer

Recruiting
NCT05864534Phase 2

Phase 2a Immune Modulation With Ultrasound for Newly Diagnosed Glioblastoma

Recruiting
NCT07578337Phase 2

A Clinical Study Evaluating a New Treatment Strategy for Patients With Advanced Pancreatic Cancer Who Have Not Received Prior Treatment for Advanced Disease.

Not Yet Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
36