Success Metrics

Clinical Success Rate
60.0%

Based on 3 completed trials

Completion Rate
60%(3/5)
Active Trials
26(74%)
Results Posted
33%(1 trials)
Terminated
2(6%)

Phase Distribution

Ph early_phase_1
1
3%
Ph phase_1
8
23%
Ph phase_2
23
66%
Ph phase_3
2
6%

Phase Distribution

9

Early Stage

23

Mid Stage

2

Late Stage

Phase Distribution34 total trials
Early Phase 1First-in-human
1(2.9%)
Phase 1Safety & dosage
8(23.5%)
Phase 2Efficacy & side effects
23(67.6%)
Phase 3Large-scale testing
2(5.9%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

50.0%

3 of 6 finished

Non-Completion Rate

50.0%

3 ended early

Currently Active

26

trials recruiting

Total Trials

35

all time

Status Distribution
Active(27)
Completed(3)
Terminated(3)
Other(2)

Detailed Status

Recruiting15
Active, not recruiting11
Completed3
Terminated2
Withdrawn1
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
35
Active
26
Success Rate
60.0%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (2.9%)
Phase 18 (23.5%)
Phase 223 (67.6%)
Phase 32 (5.9%)

Trials by Status

completed39%
terminated26%
withdrawn13%
active_not_recruiting1131%
not_yet_recruiting13%
unknown13%
recruiting1543%
suspended13%

Recent Activity

Clinical Trials (35)

Showing 20 of 35 trialsScroll for more
NCT07551596Phase 2

Testing the Combination of Anti-Cancer Drugs, Botensilimab (AGEN1181) and Balstilimab (AGEN2034), After Standard Treatment for Colorectal Cancer, Combat Trial

Recruiting
NCT05864534Phase 2

Phase 2a Immune Modulation With Ultrasound for Newly Diagnosed Glioblastoma

Active Not Recruiting
NCT07227636Phase 2

A Study of Botensilimab and Balstilimab for Colorectal Cancer With ctDNA+ After Surgery and Chemotherapy

Recruiting
NCT07516366Phase 2

Testing the Safety and Feasibility of Immunotherapy Drugs, Botensilimab and Balstilimab, Before Surgery for Clear Cell Renal Cell Carcinoma, NEO RoBOT Trial

Recruiting
NCT05845450Phase 2

Pre-operative Targeted Treatments in Molecularly Selected Resectable Colorectal Cancer (UNICORN)

Recruiting
NCT05672316Phase 1

Botensilimab, Balstilimab and Regorafenib for the Treatment of Patients With Microsatellite Stable Metastatic Colorectal Cancer Who Have Progressed on Prior Chemotherapy

Active Not Recruiting
NCT05627635Phase 1

FOLFOX and Bevacizumab in Combination With Botensilimab and Balstilimab (3B-FOLFOX) for the Treatment of Microsatellite Stable (MSS) Metastatic Colorectal Cancer

Active Not Recruiting
NCT06843551Phase 2

The Miami "EMPIRE" Trial - Eradication of Metastatic Pancreatic Cancer With Immuno-Radiation

Recruiting
NCT07735624Phase 2

RECTIFY-1: Neoadjuvant Botensilimab + Balstilimab in MSS/pMMR Early Rectal Cancer

Recruiting
NCT06411691Phase 1

KRAS-Targeted Vaccine Combined With Balstilimab and Botensilimab for Patients With Stage IV MMR-p Colorectal Cancer and Pancreatic Ductal Cancer

Recruiting
NCT07152821Phase 3

Botensilimab + Balstilimab vs Best Supportive Care as Therapy in Chemo-refractory, Unresectable, Colorectal Adenocarcinoma

Terminated
NCT05632328Phase 2

AGEN1423 and Botensilimab w/ or w/o Chemo in PDAC

Active Not Recruiting
NCT07595874Phase 2

Neoadjuvant Botensilimab and Balstilimab for the Treatment of Advanced Resectable Colorectal Cancer NEST3

Recruiting
NCT06780787Phase 2

FOLFOX, Botensilimab, and Balstilimab for the Treatment of Localized Rectal Cancer Before Surgery

Recruiting
NCT06346197Phase 3

Combination of Immune Checkpoint in Locally Advanced or Metastatic MSI/dMMR Esogastric Adenocarcinomas

Recruiting
NCT06076837Phase 1

The Seven Trial: Exploiting the Unfolded Protein Response

Terminated
NCT06843434Phase 2

A Study of Botensilimab and Balstilimab for Rectal Adenocarcinoma

Recruiting
NCT05630183Phase 2

A Study of Botensilimab in Participants With Metastatic Pancreatic Cancer

Completed
NCT05571293Phase 2

Combination Immunotherapy in Colorectal Cancer

Active Not Recruiting
NCT06300463Phase 2

Platform Study of Immunotherapy Combinations in Colorectal Cancer Liver Metastases

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
35