Success Metrics

Clinical Success Rate
80.0%

Based on 368 completed trials

Completion Rate
80%(368/460)
Active Trials
115(17%)
Results Posted
65%(241 trials)
Terminated
92(14%)

Phase Distribution

Ph phase_3
83
12%
Ph early_phase_1
4
1%
Ph phase_4
13
2%
Ph not_applicable
13
2%
Ph phase_1
209
31%
Ph phase_2
323
48%

Phase Distribution

213

Early Stage

323

Mid Stage

96

Late Stage

Phase Distribution645 total trials
Early Phase 1First-in-human
4(0.6%)
Phase 1Safety & dosage
209(32.4%)
Phase 2Efficacy & side effects
323(50.1%)
Phase 3Large-scale testing
83(12.9%)
Phase 4Post-market surveillance
13(2.0%)
N/ANon-phased studies
13(2.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

75.4%

368 of 488 finished

Non-Completion Rate

24.6%

120 ended early

Currently Active

115

trials recruiting

Total Trials

667

all time

Status Distribution
Active(123)
Completed(368)
Terminated(120)
Other(56)

Detailed Status

Completed368
Terminated92
Active, not recruiting62
unknown56
Recruiting53
Withdrawn28

Development Timeline

Analytics

Development Status

Total Trials
667
Active
115
Success Rate
80.0%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (0.6%)
Phase 1209 (32.4%)
Phase 2323 (50.1%)
Phase 383 (12.9%)
Phase 413 (2.0%)
N/A13 (2.0%)

Trials by Status

unknown568%
withdrawn284%
completed36855%
recruiting538%
terminated9214%
active_not_recruiting629%
not_yet_recruiting81%

Recent Activity

Clinical Trials (667)

Showing 20 of 667 trialsScroll for more
NCT00720785Phase 1

Natural Killer Cells and Bortezomib to Treat Cancer

Completed
NCT04414475Phase 2

A Study of Selinexor (Seli) + Low-dose Dexamethasone (LDD) in Penta-refractory Multiple Myeloma (MM), Seli and Bortezomib + LDD in Triple-class Refractory MM.

Recruiting
NCT05519085Phase 3

A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)

Recruiting
NCT07222761Phase 3

A Study to Compare Linvoseltamab Monotherapy and Linvoseltamab + Carfilzomib Combination Therapy With Standard-of-Care Combination Regimens in Adult Participants With Relapsed/Refractory Multiple Myeloma (RRMM)

Recruiting
NCT07391657Phase 3

A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA) and CD19, Versus Standard Regimens in Participants With Relapsed Refractory Multiple Myeloma (DURGA-4)

Recruiting
NCT00092222Phase 2

Virotherapy and Natural History Study of KHSV-Associated Multricentric Castleman s Disease With Correlates of Disease Activity

Active Not Recruiting
NCT04722146Phase 1

A Study of Teclistamab With Other Anticancer Therapies in Participants With Multiple Myeloma

Active Not Recruiting
NCT04181827Phase 3

A Study Comparing JNJ-68284528, a CAR-T Therapy Directed Against B-cell Maturation Antigen (BCMA), Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) or Daratumumab, Pomalidomide and Dexamethasone (DPd) in Participants With Relapsed and Lenalidomide-Refractory Multiple Myeloma

Active Not Recruiting
NCT05250973Phase 2

A Study of Daratumumab-Based Therapies in Participants With Amyloid Light Chain (AL) Amyloidosis

Active Not Recruiting
NCT07665450Phase 3

A Study of Ramantamig Plus Daratumumab Versus Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone (DVRd) or Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Participants With NDMM For Whom Stem Cell Transplant is Not Planned

Recruiting
NCT06169215Phase 2

Comparing the Combination of Selinexor-Daratumumab-Velcade-Dexamethasone (Dara-SVD) With the Usual Treatment (Dara-RVD) for High-Risk Newly Diagnosed Multiple Myeloma

Active Not Recruiting
NCT04133636Phase 2

A Study of JNJ-68284528, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against B-cell Maturation Antigen (BCMA) in Participants With Multiple Myeloma

Active Not Recruiting
NCT05623020Phase 3

A Study to Learn About the Effects of the Combination of Elranatamab, Daratumumab and Lenalidomide Compared With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Who Are Not Candidates for Transplant

Recruiting
NCT04923893Phase 3

A Study of Bortezomib, Lenalidomide and Dexamethasone (VRd) Followed by Cilta-cel, a CAR-T Therapy Directed Against BCMA Versus VRd Followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants With Newly Diagnosed Multiple Myeloma for Whom ASCT is Not Planned as Initial Therapy

Active Not Recruiting
NCT06208150Phase 3

A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide

Active Not Recruiting
NCT05083169Phase 3

A Study of Teclistamab in Combination With Daratumumab Subcutaneously (SC) (Tec-Dara) Versus Daratumumab SC, Pomalidomide, and Dexamethasone (DPd) or Daratumumab SC, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma

Active Not Recruiting
NCT06577025Phase 2

A Study of Different Sequences of Cilta-cel, Talquetamab in Combination With Daratumumab and Teclistamab in Combination With Daratumumab Following Induction With Daratumumab, Bortezomib, Lenalidomide and Dexamethasone in Participants With Standard-risk Newly Diagnosed Multiple Myeloma

Active Not Recruiting
NCT07652905Phase 2

CM336 Plus Isa-VR in Newly Diagnosed Primary Plasma Cell Leukemia

Recruiting
NCT03004287Phase 2

2015-12: A Study Exploring the Use of Early and Late Consolidation/Maintenance Therapy

Active Not Recruiting
NCT01861314Phase 1

Bortezomib, Sorafenib Tosylate, and Decitabine in Treating Patients With Acute Myeloid Leukemia

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
667