Success Metrics

Clinical Success Rate
79.9%

Based on 366 completed trials

Completion Rate
80%(366/458)
Active Trials
108(16%)
Results Posted
65%(239 trials)
Terminated
92(14%)

Phase Distribution

Ph phase_4
13
2%
Ph not_applicable
13
2%
Ph phase_1
209
32%
Ph phase_2
322
49%
Ph early_phase_1
4
1%
Ph phase_3
80
12%

Phase Distribution

213

Early Stage

322

Mid Stage

93

Late Stage

Phase Distribution641 total trials
Early Phase 1First-in-human
4(0.6%)
Phase 1Safety & dosage
209(32.6%)
Phase 2Efficacy & side effects
322(50.2%)
Phase 3Large-scale testing
80(12.5%)
Phase 4Post-market surveillance
13(2.0%)
N/ANon-phased studies
13(2.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

75.5%

366 of 485 finished

Non-Completion Rate

24.5%

119 ended early

Currently Active

108

trials recruiting

Total Trials

662

all time

Status Distribution
Active(121)
Completed(366)
Terminated(119)
Other(56)

Detailed Status

Completed366
Terminated92
Active, not recruiting59
unknown56
Recruiting49
Withdrawn27

Development Timeline

Analytics

Development Status

Total Trials
662
Active
108
Success Rate
79.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (0.6%)
Phase 1209 (32.6%)
Phase 2322 (50.2%)
Phase 380 (12.5%)
Phase 413 (2.0%)
N/A13 (2.0%)

Trials by Status

completed36655%
not_yet_recruiting132%
withdrawn274%
active_not_recruiting599%
recruiting497%
unknown568%
terminated9214%

Recent Activity

Clinical Trials (662)

Showing 20 of 662 trialsScroll for more
NCT04484623Phase 3

Belantamab Mafodotin Plus Pomalidomide and Dexamethasone (Pd) Versus Bortezomib Plus Pd in Relapsed/Refractory Multiple Myeloma

Active Not Recruiting
NCT06158841Phase 3

Study Assessing Activity of Intravenous (IV) Etentamig Monotherapy Versus Standard Available Therapies in Adult Participants With Relapsed or Refractory Multiple Myeloma

Recruiting
NCT06956170Phase 3

All Japanese Population: Belantamab Mafodotin Plus Pomalidomide and Dexamethasone (Pd) Versus Bortezomib Plus Pd in Relapsed/Refractory Multiple Myeloma

Active Not Recruiting
NCT00644228Phase 3

Lenalidomide and Dexamethasone With or Without Bortezomib in Treating Patients With Previously Untreated Multiple Myeloma

Active Not Recruiting
NCT07391657Phase 3

A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA) and CD19, Versus Standard Regimens in Participants With Relapsed Refractory Multiple Myeloma (DURGA-4)

Recruiting
NCT05561387Phase 3

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

Recruiting
NCT05519085Phase 3

A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)

Recruiting
NCT07227311Phase 2

A Study to Evaluate the Efficacy and Safety of Belantamab Mafodotin in Combination With Standard of Care in Participants With Relapsed-Refractory Multiple Myeloma (RRMM)

Recruiting
NCT07637526

Study to Evaluate Efficacy and Safety of Belantamab-based Combinations for Relapsed Multiple Myeloma

Not Yet Recruiting
NCT05623020Phase 3

A Study to Learn About the Effects of the Combination of Elranatamab, Daratumumab and Lenalidomide Compared With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Who Are Not Candidates for Transplant

Recruiting
NCT07635511Phase 3

Acalabrutinib Maleate and Bortezomib for Patients With HLA Antibodies

Not Yet Recruiting
NCT06348147Phase 2

Dara-RVd Induction for Newly Diagnosed Multiple Myeloma With Autologous Stem Cell Transplantation

Withdrawn
NCT00720785Phase 1

Natural Killer Cells and Bortezomib to Treat Cancer

Completed
NCT07018050Phase 2

Phase II Study of QLS32015 Combination Therapy in the Treatment of Multiple Myeloma

Recruiting
NCT04722146Phase 1

A Study of Teclistamab With Other Anticancer Therapies in Participants With Multiple Myeloma

Active Not Recruiting
NCT04923893Phase 3

A Study of Bortezomib, Lenalidomide and Dexamethasone (VRd) Followed by Cilta-cel, a CAR-T Therapy Directed Against BCMA Versus VRd Followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants With Newly Diagnosed Multiple Myeloma for Whom ASCT is Not Planned as Initial Therapy

Active Not Recruiting
NCT06152575Phase 3

MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)

Recruiting
NCT05250973Phase 2

A Study of Daratumumab-Based Therapies in Participants With Amyloid Light Chain (AL) Amyloidosis

Active Not Recruiting
NCT04133636Phase 2

A Study of JNJ-68284528, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against B-cell Maturation Antigen (BCMA) in Participants With Multiple Myeloma

Active Not Recruiting
NCT06577025Phase 2

A Study of Different Sequences of Cilta-cel, Talquetamab in Combination With Daratumumab and Teclistamab in Combination With Daratumumab Following Induction With Daratumumab, Bortezomib, Lenalidomide and Dexamethasone in Participants With Standard-risk Newly Diagnosed Multiple Myeloma

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
662