Success Metrics

Clinical Success Rate
79.7%

Based on 361 completed trials

Completion Rate
80%(361/453)
Active Trials
112(17%)
Results Posted
66%(239 trials)
Terminated
92(14%)

Phase Distribution

Ph phase_2
321
49%
Ph phase_4
13
2%
Ph not_applicable
13
2%
Ph phase_1
207
32%
Ph early_phase_1
4
1%
Ph phase_3
79
12%

Phase Distribution

211

Early Stage

321

Mid Stage

92

Late Stage

Phase Distribution637 total trials
Early Phase 1First-in-human
4(0.6%)
Phase 1Safety & dosage
207(32.5%)
Phase 2Efficacy & side effects
321(50.4%)
Phase 3Large-scale testing
79(12.4%)
Phase 4Post-market surveillance
13(2.0%)
N/ANon-phased studies
13(2.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

75.4%

361 of 479 finished

Non-Completion Rate

24.6%

118 ended early

Currently Active

112

trials recruiting

Total Trials

657

all time

Status Distribution
Active(121)
Completed(361)
Terminated(118)
Other(57)

Detailed Status

Completed361
Terminated92
Active, not recruiting63
unknown56
Recruiting49
Withdrawn26

Development Timeline

Analytics

Development Status

Total Trials
657
Active
112
Success Rate
79.7%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (0.6%)
Phase 1207 (32.5%)
Phase 2321 (50.4%)
Phase 379 (12.4%)
Phase 413 (2.0%)
N/A13 (2.0%)

Trials by Status

terminated9214%
unknown569%
recruiting497%
not_yet_recruiting91%
active_not_recruiting6310%
completed36155%
withdrawn264%
suspended10%

Recent Activity

Clinical Trials (657)

Showing 20 of 657 trialsScroll for more
NCT06083922Phase 2

A Study of CyBorD (Cyclophosphamide, Bortezomib, Dexamethasone) Plus Daratumumab in People With Monoclonal Gammopathy of Renal Significance (MGRS)

Recruiting
NCT06152575Phase 3

MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)

Recruiting
NCT00479128Phase 1

Bortezomib With Gemcitabine/Doxorubicin in Patients With Urothelial Cancer and Other Solid Tumors

Active Not Recruiting
NCT03763162Phase 2

Daratumumab, Bortezomib, and Dexamethasone Followed by Daratumumab, Ixazomib, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma

Active Not Recruiting
NCT02719613Phase 2

Continuing Treatment for Participants Who Have Participated in a Prior Protocol Investigating Elotuzumab

Completed
NCT05623020Phase 3

A Study to Learn About the Effects of the Combination of Elranatamab, Daratumumab and Lenalidomide Compared With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Who Are Not Candidates for Transplant

Recruiting
NCT00092222Phase 2

Virotherapy and Natural History Study of KHSV-Associated Multricentric Castleman s Disease With Correlates of Disease Activity

Active Not Recruiting
NCT04181827Phase 3

A Study Comparing JNJ-68284528, a CAR-T Therapy Directed Against B-cell Maturation Antigen (BCMA), Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) or Daratumumab, Pomalidomide and Dexamethasone (DPd) in Participants With Relapsed and Lenalidomide-Refractory Multiple Myeloma

Active Not Recruiting
NCT05250973Phase 2

A Study of Daratumumab-Based Therapies in Participants With Amyloid Light Chain (AL) Amyloidosis

Active Not Recruiting
NCT05572515Phase 3

A Study Comparing Teclistamab Monotherapy Versus Pomalidomide, Bortezomib, Dexamethasone (PVd) or Carfilzomib, Dexamethasone (Kd) in Participants With Relapsed or Refractory Multiple Myeloma

Active Not Recruiting
NCT00644228Phase 3

Lenalidomide and Dexamethasone With or Without Bortezomib in Treating Patients With Previously Untreated Multiple Myeloma

Active Not Recruiting
NCT01861314Phase 1

Bortezomib, Sorafenib Tosylate, and Decitabine in Treating Patients With Acute Myeloid Leukemia

Active Not Recruiting
NCT06169215Phase 2

Comparing the Combination of Selinexor-Daratumumab-Velcade-Dexamethasone (Dara-SVD) With the Usual Treatment (Dara-RVD) for High-Risk Newly Diagnosed Multiple Myeloma

Active Not Recruiting
NCT04923893Phase 3

A Study of Bortezomib, Lenalidomide and Dexamethasone (VRd) Followed by Cilta-cel, a CAR-T Therapy Directed Against BCMA Versus VRd Followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants With Newly Diagnosed Multiple Myeloma for Whom ASCT is Not Planned as Initial Therapy

Active Not Recruiting
NCT04133636Phase 2

A Study of JNJ-68284528, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against B-cell Maturation Antigen (BCMA) in Participants With Multiple Myeloma

Active Not Recruiting
NCT07513129Phase 1

A Phase 1 Study Of Venetoclax, Dexamethasone, Bortezomib, And Daratumumab (VDBD) For Adolescent And Young Adult Patients With Relapsed Or Refractory T-Cell Acute Lymphoblastic Leukemia And Lymphomas

Not Yet Recruiting
NCT04722146Phase 1

A Study of Teclistamab With Other Anticancer Therapies in Participants With Multiple Myeloma

Active Not Recruiting
NCT06577025Phase 2

A Study of Different Sequences of Cilta-cel, Talquetamab in Combination With Daratumumab and Teclistamab in Combination With Daratumumab Following Induction With Daratumumab, Bortezomib, Lenalidomide and Dexamethasone in Participants With Standard-risk Newly Diagnosed Multiple Myeloma

Active Not Recruiting
NCT05083169Phase 3

A Study of Teclistamab in Combination With Daratumumab Subcutaneously (SC) (Tec-Dara) Versus Daratumumab SC, Pomalidomide, and Dexamethasone (DPd) or Daratumumab SC, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma

Active Not Recruiting
NCT01695941Phase 1

Alisertib, Bortezomib, and Rituximab in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma or B-cell Low Grade Non-Hodgkin Lymphoma

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
657