Success Metrics

Clinical Success Rate
33.3%

Based on 1 completed trials

Completion Rate
33%(1/3)
Active Trials
33(85%)
Results Posted
1000%(10 trials)
Terminated
2(5%)

Phase Distribution

Ph phase_1
19
49%
Ph phase_2
16
41%
Ph early_phase_1
1
3%
Ph phase_3
3
8%

Phase Distribution

20

Early Stage

16

Mid Stage

3

Late Stage

Phase Distribution39 total trials
Early Phase 1First-in-human
1(2.6%)
Phase 1Safety & dosage
19(48.7%)
Phase 2Efficacy & side effects
16(41.0%)
Phase 3Large-scale testing
3(7.7%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

20.0%

1 of 5 finished

Non-Completion Rate

80.0%

4 ended early

Currently Active

33

trials recruiting

Total Trials

39

all time

Status Distribution
Active(34)
Completed(1)
Terminated(4)

Detailed Status

Recruiting17
Active, not recruiting16
Terminated2
Withdrawn2
Not yet recruiting1
Completed1

Development Timeline

Analytics

Development Status

Total Trials
39
Active
33
Success Rate
33.3%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (2.6%)
Phase 119 (48.7%)
Phase 216 (41.0%)
Phase 33 (7.7%)

Trials by Status

terminated25%
recruiting1744%
not_yet_recruiting13%
completed13%
withdrawn25%
active_not_recruiting1641%

Recent Activity

Clinical Trials (39)

Showing 20 of 39 trialsScroll for more
NCT04847453Phase 1

Venetoclax, MLN9708 (Ixazomib Citrate) and Dexamethasone for the Treatment of Relapsed or Refractory Light Chain Amyloidosis

Active Not Recruiting
NCT02981628Phase 2

Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia

Recruiting
NCT05554328Phase 2

Testing the Use of the Combination of Selumetinib and Olaparib or Selumetinib Alone Targeted Treatment for RAS Pathway Mutant Recurrent or Persistent Ovarian and Endometrial Cancers, A ComboMATCH Treatment Trial

Recruiting
NCT04609046Phase 1

Testing the Addition of Lenalidomide and Nivolumab to the Usual Treatment for Primary CNS Lymphoma

Recruiting
NCT03213704Phase 2

Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)

Active Not Recruiting
NCT03150693Phase 3

Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia

Recruiting
NCT03210714Phase 2

Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial)

Active Not Recruiting
NCT03155620Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

Active Not Recruiting
NCT02879695Phase 1

Blinatumomab and Nivolumab With or Without Ipilimumab in Treating Patients With Poor-Risk Relapsed or Refractory CD19+ Precursor B-Lymphoblastic Leukemia

Active Not Recruiting
NCT05418088Phase 1

Genetically Engineered Cells (Anti-CD19/CD20/CD22 CAR T-cells) for the Treatment of Relapsed or Refractory Lymphoid Malignancies

Recruiting
NCT02143414Phase 2

Blinatumomab and Combination Chemotherapy or Dasatinib, Prednisone, and Blinatumomab in Treating Older Patients With Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT03213652Phase 2

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

Active Not Recruiting
NCT03190915Phase 2

Trametinib in Treating Patients With Relapsed or Refractory Juvenile Myelomonocytic Leukemia

Active Not Recruiting
NCT06203912Phase 1

Donor Immune Cells (TGFbi NK Cells) and Isatuximab for the Treatment of Relapsed or Refractory Multiple Myeloma

Active Not Recruiting
NCT06222580Phase 1

SNDX-5613 and Gilteritinib for the Treatment of Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia and Concurrent MLL-Rearrangement or NPM1 Mutation

Recruiting
NCT04530565Phase 3

Testing the Use of Steroids and Tyrosine Kinase Inhibitors With Blinatumomab or Chemotherapy for Newly Diagnosed BCR-ABL-Positive Acute Lymphoblastic Leukemia in Adults

Active Not Recruiting
NCT05497804Phase 2

Combination Treatment Therapy Approaches for the Treatment of High-Risk Multiple Myeloma, REACH Trial

Active Not Recruiting
NCT04872790Phase 1

Venetoclax, Dasatinib, Prednisone, Rituximab and Blinatumomab for the Treatment of Newly Diagnosed or Relapsed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia or Mixed Phenotype Acute Leukemia

Active Not Recruiting
NCT03670966Phase 1

211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic Syndrome

Recruiting
NCT05707273Phase 1

CD19-Car T Cell Therapy for the Treatment of Older Adults With Acute Lymphoblastic Leukemia in First Remission

Active Not Recruiting

Drug Details

Intervention Type
PROCEDURE
Total Trials
39