Success Metrics

Clinical Success Rate
50.0%

Based on 2 completed trials

Completion Rate
50%(2/4)
Active Trials
32(82%)
Results Posted
500%(10 trials)
Terminated
2(5%)

Phase Distribution

Ph early_phase_1
1
3%
Ph phase_2
16
41%
Ph phase_3
3
8%
Ph phase_1
19
49%

Phase Distribution

20

Early Stage

16

Mid Stage

3

Late Stage

Phase Distribution39 total trials
Early Phase 1First-in-human
1(2.6%)
Phase 1Safety & dosage
19(48.7%)
Phase 2Efficacy & side effects
16(41.0%)
Phase 3Large-scale testing
3(7.7%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

33.3%

2 of 6 finished

Non-Completion Rate

66.7%

4 ended early

Currently Active

32

trials recruiting

Total Trials

39

all time

Status Distribution
Active(33)
Completed(2)
Terminated(4)

Detailed Status

Active, not recruiting17
Recruiting15
Completed2
Withdrawn2
Terminated2
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
39
Active
32
Success Rate
50.0%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (2.6%)
Phase 119 (48.7%)
Phase 216 (41.0%)
Phase 33 (7.7%)

Trials by Status

active_not_recruiting1744%
completed25%
not_yet_recruiting13%
recruiting1538%
withdrawn25%
terminated25%

Recent Activity

Clinical Trials (39)

Showing 20 of 39 trialsScroll for more
NCT04847453Phase 1

Venetoclax, MLN9708 (Ixazomib Citrate) and Dexamethasone for the Treatment of Relapsed or Refractory Light Chain Amyloidosis

Active Not Recruiting
NCT04530565Phase 3

Testing the Use of Steroids and Tyrosine Kinase Inhibitors With Blinatumomab or Chemotherapy for Newly Diagnosed BCR-ABL-Positive Acute Lymphoblastic Leukemia in Adults

Active Not Recruiting
NCT05554328Phase 2

Testing the Use of the Combination of Selumetinib and Olaparib or Selumetinib Alone Targeted Treatment for RAS Pathway Mutant Recurrent or Persistent Ovarian and Endometrial Cancers, A ComboMATCH Treatment Trial

Active Not Recruiting
NCT04609046Phase 1

Testing the Addition of Lenalidomide and Nivolumab to the Usual Treatment for Primary CNS Lymphoma

Recruiting
NCT02981628Phase 2

Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT03155620Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

Active Not Recruiting
NCT02143414Phase 2

Blinatumomab and Combination Chemotherapy or Dasatinib, Prednisone, and Blinatumomab in Treating Older Patients With Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT03190915Phase 2

Trametinib in Treating Patients With Relapsed or Refractory Juvenile Myelomonocytic Leukemia

Active Not Recruiting
NCT03213652Phase 2

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

Active Not Recruiting
NCT06249191Phase 1

Mosunetuzumab With Chemotherapy for the Treatment of Patients With Untreated C-Myc Rearrangement Positive High Grade B Cell Lymphoma or Diffuse Large B Cell Lymphoma

Recruiting
NCT03150693Phase 3

Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia

Recruiting
NCT06203912Phase 1

Donor Immune Cells (TGFbi NK Cells) and Isatuximab for the Treatment of Relapsed or Refractory Multiple Myeloma

Completed
NCT04802161Phase 2

Comparing the Addition of an Anti-Cancer Drug, Pomalidomide, to the Usual Chemotherapy Treatment (Daunorubicin and Cytarabine Liposome) in Newly Diagnosed Acute Myeloid Leukemia With Myelodysplastic Syndrome-Related Changes

Active Not Recruiting
NCT06399640Phase 1

Eltanexor and Venetoclax in Relapsed or Refractory Myelodysplastic Syndrome and Acute Myeloid Leukemia

Recruiting
NCT05549661Phase 1

Onvansertib for the Treatment of Recurrent or Refractory Chronic Myelomonocytic Leukemia and Myelodysplastic Syndrome/MPN Overlap Neoplasms

Recruiting
NCT03670966Phase 1

211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic Syndrome

Recruiting
NCT03210714Phase 2

Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial)

Active Not Recruiting
NCT03213704Phase 2

Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)

Active Not Recruiting
NCT02879695Phase 1

Blinatumomab and Nivolumab With or Without Ipilimumab in Treating Patients With Poor-Risk Relapsed or Refractory CD19+ Precursor B-Lymphoblastic Leukemia

Active Not Recruiting
NCT05418088Phase 1

Genetically Engineered Cells (Anti-CD19/CD20/CD22 CAR T-cells) for the Treatment of Relapsed or Refractory Lymphoid Malignancies

Recruiting

Drug Details

Intervention Type
PROCEDURE
Total Trials
39