Success Metrics

Clinical Success Rate
79.4%

Based on 27 completed trials

Completion Rate
79%(27/34)
Active Trials
0(0%)
Results Posted
89%(24 trials)
Terminated
7(17%)

Phase Distribution

Ph not_applicable
2
5%
Ph phase_2
6
15%
Ph phase_1
7
17%
Ph phase_4
6
15%
Ph early_phase_1
1
2%
Ph phase_3
14
34%

Phase Distribution

8

Early Stage

6

Mid Stage

20

Late Stage

Phase Distribution36 total trials
Early Phase 1First-in-human
1(2.8%)
Phase 1Safety & dosage
7(19.4%)
Phase 2Efficacy & side effects
6(16.7%)
Phase 3Large-scale testing
14(38.9%)
Phase 4Post-market surveillance
6(16.7%)
N/ANon-phased studies
2(5.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

69.2%

27 of 39 finished

Non-Completion Rate

30.8%

12 ended early

Currently Active

0

trials recruiting

Total Trials

41

all time

Status Distribution
Completed(27)
Terminated(12)
Other(2)

Detailed Status

Completed27
Terminated7
Withdrawn5
unknown2

Development Timeline

Analytics

Development Status

Total Trials
41
Active
0
Success Rate
79.4%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (2.8%)
Phase 17 (19.4%)
Phase 26 (16.7%)
Phase 314 (38.9%)
Phase 46 (16.7%)
N/A2 (5.6%)

Trials by Status

terminated717%
withdrawn512%
unknown25%
completed2766%

Recent Activity

Clinical Trials (41)

Showing 20 of 41 trialsScroll for more
NCT01718301Phase 3

HIV Patients With Chronic Hepatitis C Genotype 1 Infection Who Failed Previously to Peginterferon /Ribavirin

Terminated
NCT01353911Phase 2

Grazoprevir (MK-5172) Administered With Peginterferon and Ribavirin in Treatment-Naïve Participants With Chronic Hepatitis C (MK-5172-003)

Completed
NCT02333292

Efficacy and Safety of Therapy Against HCV Based on Direct-acting Antivirals in Real-life Conditions

Completed
NCT00910624Phase 3

Boceprevir Treatment in Participants With Chronic Hepatitis C Genotype 1 Deemed Nonresponders to Peginterferon/Ribavirin (P05514)

Completed
NCT01425203Phase 3

The Effect of Boceprevir in Russian Participants Diagnosed With Chronic Hepatitis C Genotype 1 (P08160)

Completed
NCT01023035Phase 3

Boceprevir/Peginterferon/Ribavirin for Chronic Hepatitis C: Erythropoietin Use Versus Ribavirin Dose Reduction for Anemia (P06086 AM2)

Completed
NCT01590225Phase 3

Efficacy and Safety of Boceprevir in Combination With Peginterferon Alfa-2b Plus Ribavirin in Pediatric Subjects With Chronic Hepatitis C Genotype 1 (P08034)

Withdrawn
NCT01288417Phase 1

Pharmacokinetic Study of the HCV Protease Inhibitor Boceprevir and the HIV Integrase Inhibitor Raltegravir

Completed
NCT01470690Phase 1

Pharmacokinetic Study of the HCV Protease Inhibitor Bo-cePRevir and the Proton Pump Inhibitor OMeprazOle (PROMO)

Completed
NCT01544920Phase 3

Safety and Efficacy of Boceprevir/Peginterferon Alfa-2a/Ribavirin in Interleukin-28B CC Allele-Positive Chronic Hepatitis C Virus (HCV) Genotype 1 Participants (P07755)

Completed
NCT00689390Phase 2

Three-year Follow-up of Participants After Administration of Boceprevir or Narlaprevir for the Treatment of Chronic Hepatitis C (P05063)

Terminated
NCT01425190Phase 1

Pharmacokinetics of Boceprevir in Pediatric Subjects With Chronic Hepatitis C Genotype 1 (P07614)

Terminated
NCT01756079Phase 4

A Study to Evaluate the Efficacy and Safety of Boceprevir Added to Standard of Care Therapy in Previously Treated Participants With Chronic Hepatitis C Genotype 1 and Cirrhosis (MK-3034-105)

Completed
NCT01945294Phase 3

Short Duration Versus Standard Response-Guided Therapy With Boceprevir Combined With PegIntron and Ribavirin in Previously Untreated Non-Cirrhotic Asian Participants With Chronic HCV Genotype 1 (MK-3034-107)

Completed
NCT01657552Phase 1

Eltrombopag/Boceprevir and Eltrombopag/Telaprevir Drug-Drug Interaction Study In Healthy Adult Subjects

Completed
NCT00705432Phase 3

Safety and Efficacy of Boceprevir in Previously Untreated Subjects With Chronic Hepatitis C Genotype 1 (Study P05216AM2) (COMPLETED)

Completed
NCT00845065Phase 3

Boceprevir in Combination With Peginterferon Alfa-2a and Ribavirin in Participants With Chronic Hepatitis C Genotype 1 Who Failed Prior Treatment With Peginterferon/Ribavirin (Study P05685AM2)(COMPLETED)

Completed
NCT01396005Phase 1

A Study to Evaluate the Pharmacokinetic Effect of SCH 503034 (Boceprevir) on Methadone or Buprenorphine/Naloxone Plasma Concentrations (P08123)

Completed
NCT01181804Phase 1

Comparison of Safety and Resulting Blood Level Profiles After Administration of a New Boceprevir Tablet Versus Its Current Capsule Formulation for Treatment of Chronic Hepatitis C (P06992)(COMPLETED)

Completed
NCT00959699Phase 2

A Phase 2b, Safety and Efficacy Study of Boceprevir in Patients Coinfected With HIV and Hepatitis C (P05411 AM4)

Completed

Drug Details

Intervention Type
DRUG
Total Trials
41