Success Metrics

Clinical Success Rate
90.6%

Based on 29 completed trials

Completion Rate
91%(29/32)
Active Trials
0(0%)
Results Posted
59%(17 trials)
Terminated
3(9%)

Phase Distribution

Ph phase_2
12
38%
Ph phase_1
17
53%
Ph phase_3
3
9%

Phase Distribution

17

Early Stage

12

Mid Stage

3

Late Stage

Phase Distribution32 total trials
Phase 1Safety & dosage
17(53.1%)
Phase 2Efficacy & side effects
12(37.5%)
Phase 3Large-scale testing
3(9.4%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

90.6%

29 of 32 finished

Non-Completion Rate

9.4%

3 ended early

Currently Active

0

trials recruiting

Total Trials

32

all time

Status Distribution
Completed(29)
Terminated(3)

Detailed Status

Completed29
Terminated3

Development Timeline

Analytics

Development Status

Total Trials
32
Active
0
Success Rate
90.6%
Most Advanced
Phase 3

Trials by Phase

Phase 117 (53.1%)
Phase 212 (37.5%)
Phase 33 (9.4%)

Trials by Status

completed2991%
terminated39%

Recent Activity

Clinical Trials (32)

Showing 20 of 32 trialsScroll for more
NCT01346540Phase 1

A Phase I/II Study of Continuous Oral Treatment With BIBF 1120 Added to Standard Gemcitabine/Cisplatin Therapy in First Line NSCLC Patients With Squamous Cell Histology.

Completed
NCT02182245Phase 1

Dose Escalation Study of BIBF 1120 in Patients With Advanced Gynaecological Malignancies

Completed
NCT02182219Phase 1

Oral Treatment With BIBF 1120 Together With Docetaxel and Prednisone in Patients With Hormone Refractory Prostate Cancer

Completed
NCT01485874Phase 1

Doxorubicin + BIBF 1120 in Patients for Ovarian Cancer

Terminated
NCT01024920Phase 2

Compare Safety and Efficacy of BIBF 1120 Versus Sunitinib.

Completed
NCT02389764Phase 2

Nintedanib For HER2-Negative Metastatic Inflammatory Breast Cancer (MIBC)

Terminated
NCT01170065Phase 2

Roll Over Study From 1199.30 BIBF 1120 in Idiopathic Pulmonary Fibrosis (IPF)

Completed
NCT01610869Phase 2

Low Dose Cyclophosphamide +/-- Nintedanib in Advanced Ovarian Cancer

Completed
NCT01669798Phase 2

BIBF 1120 in Bevacizumab Resistant, Persistent, or Recurrent Epithelial Ovarian Cancer

Completed
NCT01022853Phase 1

Combination of BI6727 (Volasertib) and BIBF1120 in Solid Tumors

Completed
NCT01015118Phase 3

LUME-Ovar 1: Nintedanib (BIBF 1120) or Placebo in Combination With Paclitaxel and Carboplatin in First Line Treatment of Ovarian Cancer

Completed
NCT01666600Phase 1

NOA-12: BIBF1120 and R-RT in Glioblastoma

Terminated
NCT01004003Phase 2

Phase I/II Comparison of Efficacy and Safety of BIBF 1120 and Sorafenib in Patients With Advanced Hepatocellular Carcinoma

Completed
NCT01441297Phase 2

BIBF 1120 as Second Line Treatment for Small Cell Lung Cancer

Completed
NCT01335477Phase 3

Safety and Efficacy of BIBF 1120 at High Dose in Idiopathic Pulmonary Fibrosis Patients II

Completed
NCT01335464Phase 3

Safety and Efficacy of BIBF 1120 at High Dose in Idiopathic Pulmonary Fibrosis Patients

Completed
NCT00987935Phase 2

A Phase I / II Trial of Nintedanib in Asian Hepatocellular Carcinoma Patients

Completed
NCT01684111Phase 1

An Dose Escalation Trial of Oral BIBF 1120 in Combination With Intravenous Vinorelbine in Elderly Patients With Advanced Non Small Lung Cell Cancer - Stage IV (VENUS-1)

Completed
NCT00998296Phase 1

Phase I Dose Escalation Study of Concomitant BIBF 1120 and BIBW 2992 in Patients With Advanced Solid Tumours.

Completed
NCT00904839Phase 2

BIBF 1120 Versus Bevacizumab in Metastatic Colorectal Cancer

Completed

Drug Details

Intervention Type
DRUG
Total Trials
32