Success Metrics

Clinical Success Rate
85.7%

Based on 12 completed trials

Completion Rate
86%(12/14)
Active Trials
0(0%)
Results Posted
117%(14 trials)
Terminated
2(14%)

Phase Distribution

Ph phase_2
4
29%
Ph phase_1
10
71%

Phase Distribution

10

Early Stage

4

Mid Stage

0

Late Stage

Phase Distribution14 total trials
Phase 1Safety & dosage
10(71.4%)
Phase 2Efficacy & side effects
4(28.6%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

85.7%

12 of 14 finished

Non-Completion Rate

14.3%

2 ended early

Currently Active

0

trials recruiting

Total Trials

14

all time

Status Distribution
Completed(12)
Terminated(2)

Detailed Status

Completed12
Terminated2

Development Timeline

Analytics

Development Status

Total Trials
14
Active
0
Success Rate
85.7%
Most Advanced
Phase 2

Trials by Phase

Phase 110 (71.4%)
Phase 24 (28.6%)

Trials by Status

terminated214%
completed1286%

Recent Activity

Clinical Trials (14)

Showing 14 of 14 trials
NCT03754959Phase 1

This Study in Healthy Men Tests How Different Doses of BI 1358894 Are Taken up in the Body and How Well They Are Tolerated. The Study Also Tests How BI 1358894 Affects the Way the Body Breaks Down Midazolam

Completed
NCT04426851Phase 1

A Study in Healthy Men to Test How BI 1358894 is Taken up in the Body and How Food Influences the Amount of BI 1358894 in the Blood

Completed
NCT03210272Phase 1

This Study in Healthy Men Tests How Different Doses of BI 1358894 Are Taken up in the Body and How Well They Are Tolerated. The Study Also Looks at How Food Influences the Amount of BI 1358894 in the Blood

Completed
NCT03904576Phase 1

A Study in Healthy Men to Test Whether BI 1358894 Reduces Druginduced Panic Symptoms

Completed
NCT04521478Phase 2

A Study to Test the Effect of Different Doses of BI 1358894 and Quetiapine in People With Depression

Completed
NCT04567316Phase 1

A Study in Healthy Men to Test How BI 1358894 is Taken up and Handled by the Body

Completed
NCT04099732Phase 1

A Study in Healthy Men to Test the Influence of BI 1358894 on the Amount of the Medicines Rosuvastatin and Dabigatran in the Blood

Completed
NCT03854578Phase 1

A Study in People With Depression to Test the Effects of BI 1358894 on Parts of the Brain That Are Involved in Emotions

Completed
NCT05934942Phase 1

A Study in Healthy Women to Test Whether BI 1358894 Influences the Amount of a Contraceptive in the Blood

Terminated
NCT04899674Phase 1

A Study in Healthy Men and Women to Test Whether BI 1358894 Influences the Amount of Bupropion in the Blood

Completed
NCT03843151Phase 1

A Study in Healthy Men to Test How Itraconazole Influences the Amount of BI 1358894 in the Blood

Completed
NCT05103657Phase 2

A Study to Test Whether Taking BI 1358894 for 8 Weeks Helps Adults With Post-traumatic Stress Disorder

Completed
NCT04566601Phase 2

A Study to Test Different Doses of BI 1358894 and Find Out Whether They Reduce Symptoms in People With Borderline Personality Disorder

Completed
NCT04423757Phase 2

A Home-based Study Using Mobile Technology to Test Whether BI 1358894 is Effective in People With Depression

Terminated

All 14 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
14