Success Metrics

Clinical Success Rate
100.0%

Based on 28 completed trials

Completion Rate
100%(28/28)
Active Trials
3(6%)
Results Posted
4%(1 trials)

Phase Distribution

Ph phase_4
16
31%
Ph phase_3
4
8%
Ph phase_1
3
6%
Ph not_applicable
23
45%
Ph phase_2
5
10%

Phase Distribution

3

Early Stage

5

Mid Stage

20

Late Stage

Phase Distribution51 total trials
Phase 1Safety & dosage
3(5.9%)
Phase 2Efficacy & side effects
5(9.8%)
Phase 3Large-scale testing
4(7.8%)
Phase 4Post-market surveillance
16(31.4%)
N/ANon-phased studies
23(45.1%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

96.6%

28 of 29 finished

Non-Completion Rate

3.4%

1 ended early

Currently Active

3

trials recruiting

Total Trials

51

all time

Status Distribution
Active(11)
Completed(28)
Terminated(1)
Other(11)

Detailed Status

Completed28
unknown11
Not yet recruiting5
Enrolling by invitation3
Recruiting2
Active, not recruiting1

Development Timeline

Analytics

Development Status

Total Trials
51
Active
3
Success Rate
100.0%
Most Advanced
Phase 4

Trials by Phase

Phase 13 (5.9%)
Phase 25 (9.8%)
Phase 34 (7.8%)
Phase 416 (31.4%)
N/A23 (45.1%)

Trials by Status

active_not_recruiting12%
enrolling_by_invitation36%
unknown1122%
withdrawn12%
not_yet_recruiting510%
completed2855%
recruiting24%

Recent Activity

Clinical Trials (51)

Showing 20 of 51 trialsScroll for more
NCT07480018Not Applicable

Berberine Supplementation, Sprint Interval Training, and Immune Function Study

Active Not Recruiting
NCT07420231Not Applicable

Evaluation of the Synergistic Effect of Combining a Prebiotic and a Postbiotic on Intestinal Discomfort

Recruiting
NCT07541898Not Applicable

Effects of Berberine on Cardiometabolic Outcomes

Not Yet Recruiting
NCT07356765Not Applicable

Berberine in Treating Negative Symptoms of Schizophrenia: Clinical Efficacy and Mechanisms

Enrolling By Invitation
NCT07359209Not Applicable

Berberine Improving Cognitive Impairments in Schizophrenia

Enrolling By Invitation
NCT05720299Not Applicable

A Clinical Study to Evaluate the Effects of Akkermansia Muciniphila and Berberine on Prediabetes Among Obese Subjects.

Completed
NCT03378934Phase 4

Anti-platelet Effect of Berberine in Patients After Percutaneous Coronary Intervention

Recruiting
NCT06514274Phase 4

Study on The Efficacy and Safety of Vonoprazan-containing Berberine Triple Therapy in Helicobacter Pylori First-Line Eradication

Completed
NCT06911983Not Applicable

Comparative Efficacy of Metformin and Berberine Among TCF7L2 (rs7903146) TT vs. CC Genotype Carriers With Type 2 Diabetes

Not Yet Recruiting
NCT03976336Not Applicable

Evaluating the Tolerability and Effects of Berberine on Major Metabolic Biomarkers: A Pilot Study

Completed
NCT06863922Not Applicable

A Pilot Study of Berberine (Soloways ™) in Patients with Type 2 Diabetes Mellitus Carrying TCF7L2 Polymorphisms

Completed
NCT06782646Phase 2

Study on the Sex-specific, Lipid- and Lipoprotein-lowering Effects of Berberine

Enrolling By Invitation
NCT05463003Not Applicable

Impact of OCT1 and CYP2D6 Genotypes on Pharmacokinetics of Berberine in Healthy Volunteers

Completed
NCT05845931Not Applicable

Sex Differences in Berberine Pharmacokinetics

Completed
NCT06603688Phase 4

Study on the Efficacy and Safety of Berberine, Minocycline, Esomeprazole, and Colloidal Bismuth Quadruple Therapy in the Initial Treatment of Helicobacter Pylori.

Unknown
NCT06426966Not Applicable

Gymnema Sylvestre vs Berberine in Obesity Gene Expression of Adipokines

Completed
NCT04918667Phase 1

Effect of Gamma-cyclodextrin on the Bioavailability of Berberine

Not Yet Recruiting
NCT03198572Phase 4

Efficacy and Safety of Berberine in Non-alcoholic Steatohepatitis

Unknown
NCT03548155Not Applicable

Berberine Effects on Clinical Symptoms and Metabolic Disturbance in Patients With Schizophrenia

Completed
NCT03029390Phase 4

Effect of Berberine Versus Metformin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Prediabetes

Unknown

Drug Details

Intervention Type
DIETARY SUPPLEMENT
Total Trials
51