Success Metrics

Clinical Success Rate
44.4%

Based on 4 completed trials

Completion Rate
44%(4/9)
Active Trials
0(0%)
Results Posted
200%(8 trials)
Terminated
5(56%)

Phase Distribution

Ph phase_1
4
44%
Ph phase_2
2
22%
Ph phase_3
3
33%

Phase Distribution

4

Early Stage

2

Mid Stage

3

Late Stage

Phase Distribution9 total trials
Phase 1Safety & dosage
4(44.4%)
Phase 2Efficacy & side effects
2(22.2%)
Phase 3Large-scale testing
3(33.3%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

44.4%

4 of 9 finished

Non-Completion Rate

55.6%

5 ended early

Currently Active

0

trials recruiting

Total Trials

9

all time

Status Distribution
Completed(4)
Terminated(5)

Detailed Status

Terminated5
Completed4

Development Timeline

Analytics

Development Status

Total Trials
9
Active
0
Success Rate
44.4%
Most Advanced
Phase 3

Trials by Phase

Phase 14 (44.4%)
Phase 22 (22.2%)
Phase 33 (33.3%)

Trials by Status

terminated556%
completed444%

Recent Activity

Clinical Trials (9)

Showing 9 of 9 trials
NCT04209114Phase 3

A Study of Nivolumab Plus Bempegaldesleukin (Bempeg/NKTR-214) vs Nivolumab Alone vs Standard of Care in Participants With Bladder Cancer That May Have Invaded The Muscle Wall of the Bladder and Who Cannot Get Cisplatin, A Type of Medicine Given To Treat Bladder Cancer

Completed
NCT04646044Phase 1

A Placebo Controlled Trial of Bempegaldesleukin (BEMPEG; NKTR-214) With Standard of Care in Patients With Mild COVID-19

Completed
NCT03548467Phase 1

A Study to Evaluate Safety and Efficacy of Multiple Dosing With VB10.NEO and Bempegaldesleukin (NKTR-214) Immunotherapy in Patients With Locally Advanced or Metastatic Cancer

Completed
NCT04410445Phase 3

Study to Compare Adjuvant Immunotherapy of Bempegaldesleukin Combined With Nivolumab Versus Nivolumab After Complete Resection of Melanoma in Patients at High Risk for Recurrence

Terminated
NCT03729245Phase 3

A Study of Bempegaldesleukin (NKTR-214: BEMPEG) in Combination With Nivolumab Compared With the Investigator's Choice of a Tyrosine Kinase Inhibitor (TKI) Therapy (Either Sunitinib or Cabozantinib Monotherapy) for Advanced Metastatic Renal Cell Carcinoma (RCC)

Terminated
NCT03785925Phase 2

A Single-Arm Study of Bempegaldesleukin (NKTR-214) Plus Nivolumab in Cisplatin Ineligible Patients Who Have Locally Advanced or Metastatic Urothelial Cancer

Completed
NCT03435640Phase 1

REVEAL Study of NKTR-262 in Combination With NKTR-214 and Nivolumab in Patients With Locally Advanced / Metastatic Solid Tumor Malignancies

Terminated
NCT04969861Phase 2

BEMPEG With Pembrolizumab vs Pembrolizumab Alone in Patients With Metastatic or Recurrent HNSCC (PROPEL-36)

Terminated
NCT04052204Phase 1

Avelumab With Bempegaldesleukin With or Without Talazoparib or Enzalutamide in Advanced or Metastatic Solid Tumors

Terminated

All 9 trials loaded

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
9