Success Metrics

Clinical Success Rate
85.7%

Based on 6 completed trials

Completion Rate
86%(6/7)
Active Trials
9(43%)
Results Posted
83%(5 trials)
Terminated
1(5%)

Phase Distribution

Ph phase_3
2
10%
Ph phase_4
2
10%
Ph phase_1
5
24%
Ph phase_2
12
57%

Phase Distribution

5

Early Stage

12

Mid Stage

4

Late Stage

Phase Distribution21 total trials
Phase 1Safety & dosage
5(23.8%)
Phase 2Efficacy & side effects
12(57.1%)
Phase 3Large-scale testing
2(9.5%)
Phase 4Post-market surveillance
2(9.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

75.0%

6 of 8 finished

Non-Completion Rate

25.0%

2 ended early

Currently Active

9

trials recruiting

Total Trials

21

all time

Status Distribution
Active(13)
Completed(6)
Terminated(2)

Detailed Status

Recruiting8
Completed6
Not yet recruiting4
Terminated1
Active, not recruiting1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
21
Active
9
Success Rate
85.7%
Most Advanced
Phase 4

Trials by Phase

Phase 15 (23.8%)
Phase 212 (57.1%)
Phase 32 (9.5%)
Phase 42 (9.5%)

Trials by Status

terminated15%
completed629%
not_yet_recruiting419%
recruiting838%
active_not_recruiting15%
withdrawn15%

Recent Activity

Clinical Trials (21)

Showing 20 of 21 trialsScroll for more
NCT07726914Phase 1

Study to Compare the Plasma Concentration of Belumosudil Given as an Oral Suspension and as a Tablet to Healthy Adult Male Participants

Not Yet Recruiting
NCT06082037Phase 3

A Study to Test How Effective Belumosudil Tablets Are for Treating Adult Participants With Chronic Lung Allograft Dysfunction

Recruiting
NCT07006506Phase 2

A Study of Belumosudil in People at Risk of Developing Graft-Versus-Host Disease After a Stem Cell Transplant

Recruiting
NCT04643002Phase 1

Isatuximab in Combination With Novel Agents in RRMM - Master Protocol

Recruiting
NCT07484113Phase 1

IL6-receptor Inhibitor Iwith Belumosudil for the Treatment of Belumosudil-refractory cGVHD

Not Yet Recruiting
NCT07643025Phase 2

Belumosudil With Ruxolitnib as Second Line Therapy for Chronic Graft Versus Host Disease (cGvHD) After Steroid Failure

Not Yet Recruiting
NCT05922761Phase 2

BElumosudil for Bronchiolitis Obliterans Prevention/Therapy (BEBOP)

Recruiting
NCT07116031Phase 2

A Study of Belumosudil in Children With Chronic Graft Versus Host Disease (schoolROCK)

Recruiting
NCT05996627Phase 2

Belumosudil for the Pre-emptive Treatment of Patients With Chronic Graft Versus Host Disease

Recruiting
NCT06616415Phase 4

A Clinical Study to Evaluate the Pharmacokinetics, Efficacy, and Safety of Belumosudil in Chinese Adolescents With cGVHD Who Have Had an Inadequate Response to Glucocorticoids or Other Systemic Therapies

Completed
NCT06476132Phase 2

Belumosudil to Block Chronic Lung Allograft Dysfunction (CLAD) in High Risk Lung Transplant Recipients

Recruiting
NCT07135973Phase 4

A Study to Investigate Safety of Belumosudil in Participants Aged 12 Years and Above, With Chronic Graft-versus-host Disease (cGVHD)

Not Yet Recruiting
NCT06046248Phase 2

Belumosudil and Rituximab for Primary Treatment of Chronic Graft-Versus-Host-Disease

Recruiting
NCT05567406Phase 2

Safety and Efficacy of Oral Belumosudil in Black or African American, American Indian or Alaska Native, and Native Hawaiian or Other Pacific Islander Male and Female Participants Aged 12 Years and Above With Chronic Graft Versus Host Disease (cGVHD) After At Least 2 Prior Lines of Systemic Therapy

Withdrawn
NCT06143891Phase 3

A Study to Test an Oral Medicine, Belumosudil, in Combination With Corticosteroids in Participants at Least 12 Years of Age With Newly Diagnosed Chronic Graft Versus Host Disease.

Active Not Recruiting
NCT05806567Phase 1

A Study to Assess the Effect of Oral Belumosudil on Inhibition of Various Proteins in the Fed State in Healthy Male Subjects

Completed
NCT04680975Phase 2

Efficacy and Safety of Belumosudil in Subjects With Diffuse Cutaneous Systemic Sclerosis

Terminated
NCT02688647Phase 2

A 2-Part, Phase 2 Open-label and Crossover Study of Belumosudil for Treatment of Idiopathic Pulmonary Fibrosis

Completed
NCT03530995Phase 1

Drug-drug Interaction Between Belumosudil, Itraconazole, Rifampicin, Rabeprazole, and Omeprazole in Healthy Volunteers

Completed
NCT02106195Phase 2

A Safety and Tolerability Study of Belumosudil (KD025) Treatment in Subjects With Moderately Severe Psoriasis Vulgaris

Completed

Drug Details

Intervention Type
DRUG
Total Trials
21