Success Metrics

Clinical Success Rate
79.3%

Based on 23 completed trials

Completion Rate
79%(23/29)
Active Trials
9(21%)
Results Posted
65%(15 trials)
Terminated
6(14%)

Phase Distribution

Ph phase_2
15
35%
Ph phase_3
2
5%
Ph phase_1
26
60%

Phase Distribution

26

Early Stage

15

Mid Stage

2

Late Stage

Phase Distribution43 total trials
Phase 1Safety & dosage
26(60.5%)
Phase 2Efficacy & side effects
15(34.9%)
Phase 3Large-scale testing
2(4.7%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

69.7%

23 of 33 finished

Non-Completion Rate

30.3%

10 ended early

Currently Active

9

trials recruiting

Total Trials

43

all time

Status Distribution
Active(9)
Completed(23)
Terminated(10)
Other(1)

Detailed Status

Completed23
Terminated6
Recruiting5
Withdrawn4
Active, not recruiting4
unknown1

Development Timeline

Analytics

Development Status

Total Trials
43
Active
9
Success Rate
79.3%
Most Advanced
Phase 3

Trials by Phase

Phase 126 (60.5%)
Phase 215 (34.9%)
Phase 32 (4.7%)

Trials by Status

withdrawn49%
recruiting512%
terminated614%
unknown12%
active_not_recruiting49%
completed2353%

Recent Activity

Clinical Trials (43)

Showing 20 of 43 trialsScroll for more
NCT05154994Phase 1

Tremelimumab + Durvalumab(MEDI4736)+ Belinostat in Urothelial Carcinoma

Active Not Recruiting
NCT06406465Phase 2

A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and Toxicity

Recruiting
NCT05627245Phase 1

Testing the Safety of the Anti-cancer Drugs Tazemetostat and Belinostat in Patients With Lymphomas That Have Resisted Treatment

Active Not Recruiting
NCT04340843Phase 2

Testing the Combination of Belinostat and SGI-110 (Guadecitabine) or ASTX727 for the Treatment of Unresectable and Metastatic Conventional Chondrosarcoma

Active Not Recruiting
NCT06561048Phase 3

Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymphoma

Recruiting
NCT02737046Phase 2

Belinostat Therapy With Zidovudine for Adult T-Cell Leukemia-Lymphoma

Completed
NCT03772925Phase 1

Pevonedistat and Belinostat in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

Terminated
NCT02381548Phase 1

Phase I Trial of AZD1775 and Belinostat in Treating Patients With Relapsed or Refractory Myeloid Malignancies or Untreated Acute Myeloid Leukemia

Terminated
NCT04747236Phase 2

Randomized Phase IIB Trial of Oral Azacytidine Plus Romidepsin Versus Investigator's Choice in PTCL

Recruiting
NCT07234162Phase 3

A Phase 3 Multinational Study of Golidocitinib Versus Investigator's Choice in r/r PTCL (JACKPOT19)

Recruiting
NCT05170334Phase 2

Binimetinib Plus Belinostat for Subjects With Metastatic Uveal Melanoma

Active Not Recruiting
NCT03432741Phase 1

Direct Tumor Microinjection and FDG-PET in Testing Drug Sensitivity in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma, Hodgkin Lymphoma, or Stage IV Breast Cancer

Terminated
NCT04315233Phase 1

Ribociclib&Belinostat In Patients w Metastatic Triple Neg Breast Cancer & Recurrent Ovarian Cancer w Response Prediction By Genomics

Recruiting
NCT04703920Phase 1

Talazoparib in Combination With Belinostat for Metastatic Breast Cancer, Metastatic Castration Resistant Prostate Cancer, and Metastatic Ovarian Cancer

Completed
NCT02137759Phase 2

MRSI to Predict Response to RT/TMZ ± Belinostat in GBM

Unknown
NCT04184869Phase 1

Extension Study for Patients Who Had Not Met Criteria for Discontinuation in Previous Sponsored Belinostat Trials

Completed
NCT00865969Phase 2

Belinostat in Relapsed or Refractory Peripheral T-Cell Lymphoma

Completed
NCT04315155Phase 1

Evaluating Safety & Efficacy Belinostat Combo w Nivo Alone & w Ipi in Patients w Treated Metastatic/Advanced Carcinomas w ARID1A Lof Mutation

Withdrawn
NCT01583777Phase 1

Phase I Mass Balance, PK and Safety Study of 14C-Labeled Belinostat in Patients With Advanced Cancer

Completed
NCT01839097Phase 1

Phase 1 Dose Finding Study of Belinostat for Treatment of Patients With Peripheral T-cell Lymphoma (PTCL)

Completed

Drug Details

Intervention Type
DRUG
Total Trials
43