Success Metrics

Clinical Success Rate
87.9%

Based on 29 completed trials

Completion Rate
88%(29/33)
Active Trials
11(22%)
Results Posted
24%(7 trials)
Terminated
4(8%)

Phase Distribution

Ph phase_2
12
24%
Ph phase_1
18
36%
Ph not_applicable
5
10%
Ph early_phase_1
2
4%
Ph phase_4
3
6%
Ph phase_3
7
14%

Phase Distribution

20

Early Stage

12

Mid Stage

10

Late Stage

Phase Distribution47 total trials
Early Phase 1First-in-human
2(4.3%)
Phase 1Safety & dosage
18(38.3%)
Phase 2Efficacy & side effects
12(25.5%)
Phase 3Large-scale testing
7(14.9%)
Phase 4Post-market surveillance
3(6.4%)
N/ANon-phased studies
5(10.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

85.3%

29 of 34 finished

Non-Completion Rate

14.7%

5 ended early

Currently Active

11

trials recruiting

Total Trials

50

all time

Status Distribution
Active(13)
Completed(29)
Terminated(5)
Other(3)

Detailed Status

Completed29
Active, not recruiting6
Recruiting5
Terminated4
unknown3
Not yet recruiting2

Development Timeline

Analytics

Development Status

Total Trials
50
Active
11
Success Rate
87.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 12 (4.3%)
Phase 118 (38.3%)
Phase 212 (25.5%)
Phase 37 (14.9%)
Phase 43 (6.4%)
N/A5 (10.6%)

Trials by Status

not_yet_recruiting24%
terminated48%
unknown36%
completed2958%
withdrawn12%
active_not_recruiting612%
recruiting510%

Recent Activity

Clinical Trials (50)

Showing 20 of 50 trialsScroll for more
NCT03711032Phase 3

Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Bacillus Calmette-Guerin (BCG) in High-Risk Non-Muscle Invasive Bladder Cancer (HR NMIBC) (MK-3475-676/KEYNOTE-676)

Active Not Recruiting
NCT07206225Phase 1

A Study to Learn About the Study Medicine PF-08052667 in People With Bladder Cancer

Recruiting
NCT06833073Phase 2

A Clinical Study of Intismeran Autogene (V940) and BCG in People With Bladder Cancer (V940-011/INTerpath-011)

Recruiting
NCT05947890Phase 2

Evaluating the Safety and Immunogenicity of MTBVAC

Recruiting
NCT05943106Phase 3

BCG in Combination With Durvalumab in Adult BCG-naïve, High-risk NMIBC Participants

Active Not Recruiting
NCT06050356Phase 1

First-in-Human Trial of the Novel Tuberculosis Vaccine Candidate, H107e/CAF®10b

Active Not Recruiting
NCT07268339Phase 3

A Phase III Randomised Control Clinical Trial of Radiotherapy With Radiosensitisation Versus Intravesical Bacillus Calmette-Guerin Therapy for High-risk Non-muscle Invasive Bladder Cancer.

Not Yet Recruiting
NCT03536117Phase 2

Dose-Defining Safety and Immunogenicity Study of MTBVAC in South African Neonates

Completed
NCT05387655

Long Term Effects of BCG Vaccination on Infectious and Immune Mediated Diseases

Active Not Recruiting
NCT01906853Phase 3

Melbourne Infant Study - Bacille Calmette Guérin (BCG) for Allergy & Infection Reduction

Completed
NCT04975178Phase 3

Efficacy, Safety and Immunogenicity Evaluation of MTBVAC in Newborns in Sub-Saharan Africa

Recruiting
NCT03799835Phase 3

Atezolizumab Plus One-year BCG Bladder Instillation in BCG-naive High-risk Non-muscle Invasive Bladder Cancer Patients

Active Not Recruiting
NCT04134000Phase 1

Atezolizumab and BCG in High Risk BCG naïve Non-muscle Invasive Bladder Cancer (NMIBC) Patients (BladderGATE)

Active Not Recruiting
NCT03892642Phase 1

Avelumab Plus Bacille Calmette-Guerin (BCG) in Patients With Non-muscle Invasive Bladder Cancer

Completed
NCT05626101Not Applicable

Safety and Efficacy of Scheduled Intravesical Gemcitabine Versus Intravesical BCG for Intermediate and High Risk Non Muscle Invasive Bladder Cancer: A Prospective, Randomized Study

Recruiting
NCT06178666Not Applicable

A Controlled Human Infection Model (CHIM) With Intradermal BCG in Malawi

Not Yet Recruiting
NCT04369794Phase 4

COVID-19: BCG As Therapeutic Vaccine, Transmission Limitation, and Immunoglobulin Enhancement

Completed
NCT02709278Phase 1

Aerosol BCG Challenge Trial in Healthy UK Adults

Completed
NCT05541952Phase 4

BCG Re-vaccination for Primary Tuberculosis Prophylaxis in the Prison Population

Withdrawn
NCT03519256Phase 2

A Study of Nivolumab or Nivolumab Plus Experimental Medication BMS-986205 With or Without Bacillus Calumette-Guerin (BCG) in BCG Unresponsive Bladder Cancer That Has Not Invaded Into the Muscle Wall of the Bladder

Terminated

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
50