Success Metrics

Clinical Success Rate
25.0%

Based on 1 completed trials

Completion Rate
25%(1/4)
Active Trials
27(66%)
Results Posted
100%(1 trials)
Terminated
3(7%)

Phase Distribution

Ph phase_3
2
5%
Ph early_phase_1
1
2%
Ph phase_1
12
29%
Ph phase_2
25
61%

Phase Distribution

13

Early Stage

25

Mid Stage

2

Late Stage

Phase Distribution40 total trials
Early Phase 1First-in-human
1(2.5%)
Phase 1Safety & dosage
12(30.0%)
Phase 2Efficacy & side effects
25(62.5%)
Phase 3Large-scale testing
2(5.0%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

12.5%

1 of 8 finished

Non-Completion Rate

87.5%

7 ended early

Currently Active

27

trials recruiting

Total Trials

41

all time

Status Distribution
Active(31)
Completed(1)
Terminated(7)
Other(2)

Detailed Status

Recruiting17
Active, not recruiting10
Withdrawn4
Not yet recruiting4
Terminated3
Completed1

Development Timeline

Analytics

Development Status

Total Trials
41
Active
27
Success Rate
25.0%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (2.5%)
Phase 112 (30.0%)
Phase 225 (62.5%)
Phase 32 (5.0%)

Trials by Status

withdrawn410%
active_not_recruiting1024%
completed12%
unknown12%
suspended12%
terminated37%
not_yet_recruiting410%
recruiting1741%

Recent Activity

Clinical Trials (41)

Showing 20 of 41 trialsScroll for more
NCT06411691Phase 1

KRAS-Targeted Vaccine Combined With Balstilimab and Botensilimab for Patients With Stage IV MMR-p Colorectal Cancer and Pancreatic Ductal Cancer

Recruiting
NCT07735624Phase 2

RECTIFY-1: Neoadjuvant Botensilimab + Balstilimab in MSS/pMMR Early Rectal Cancer

Not Yet Recruiting
NCT07695311Phase 1

EWSR1 Immunotherapy in Ewing Sarcoma and DSRCT

Not Yet Recruiting
NCT07152821Phase 3

Botensilimab + Balstilimab vs Best Supportive Care as Therapy in Chemo-refractory, Unresectable, Colorectal Adenocarcinoma

Terminated
NCT07595874Phase 2

Neoadjuvant Botensilimab and Balstilimab for the Treatment of Advanced Resectable Colorectal Cancer NEST3

Recruiting
NCT06780787Phase 2

FOLFOX, Botensilimab, and Balstilimab for the Treatment of Localized Rectal Cancer Before Surgery

Recruiting
NCT06346197Phase 3

Combination of Immune Checkpoint in Locally Advanced or Metastatic MSI/dMMR Esogastric Adenocarcinomas

Recruiting
NCT06076837Phase 1

The Seven Trial: Exploiting the Unfolded Protein Response

Terminated
NCT06843434Phase 2

A Study of Botensilimab and Balstilimab for Rectal Adenocarcinoma

Recruiting
NCT05891821Phase 2

Assessment of the Safety and Efficacy of Balstilimab for the Treatment of Relapsed/Refractory Lymphomas (IMMONC0001)

Recruiting
NCT05571293Phase 2

Combination Immunotherapy in Colorectal Cancer

Active Not Recruiting
NCT07551596Phase 2

Testing the Combination of Anti-Cancer Drugs, Botensilimab (AGEN1181) and Balstilimab (AGEN2034), After Standard Treatment for Colorectal Cancer, Combat Trial

Not Yet Recruiting
NCT06300463Phase 2

Platform Study of Immunotherapy Combinations in Colorectal Cancer Liver Metastases

Recruiting
NCT06251973Phase 2

A Study of agenT-797 in Combination With Botensilimab, Balstilimab, Ramucirumab, and Paclitaxel for People With Esophageal, Gastric, or Gastro-esophageal Junction Cancer

Active Not Recruiting
NCT07516366Phase 2

Testing the Safety and Feasibility of Immunotherapy Drugs, Botensilimab and Balstilimab, Before Surgery for Clear Cell Renal Cell Carcinoma, NEO RoBOT Trial

Not Yet Recruiting
NCT05864534Phase 2

Phase 2a Immune Modulation With Ultrasound for Newly Diagnosed Glioblastoma

Recruiting
NCT07128355Early Phase 1

Botensilimab, Balstilimab, and SBRT in Colorectal Cancer

Recruiting
NCT05363709Phase 2

BALSTILIMAB on Viral Clearance in HPV+ Oropharyngeal Cancer Patients

Withdrawn
NCT05572970

Expanded Access for Cancer Treatment With Balstilimab (AGEN2034) and Zalifrelimab (AGEN1884)

Unknown
NCT04028063Phase 2

Doxorubicin Plus Dual Checkpoint Blockade for Soft Tissue Sarcomas

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
41