Success Metrics

Clinical Success Rate
81.6%

Based on 62 completed trials

Completion Rate
82%(62/76)
Active Trials
29(24%)
Results Posted
73%(45 trials)
Terminated
14(11%)

Phase Distribution

Ph not_applicable
4
3%
Ph phase_3
5
4%
Ph phase_1
29
24%
Ph phase_2
73
60%

Phase Distribution

29

Early Stage

73

Mid Stage

5

Late Stage

Phase Distribution111 total trials
Phase 1Safety & dosage
29(26.1%)
Phase 2Efficacy & side effects
73(65.8%)
Phase 3Large-scale testing
5(4.5%)
N/ANon-phased studies
4(3.6%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

76.5%

62 of 81 finished

Non-Completion Rate

23.5%

19 ended early

Currently Active

29

trials recruiting

Total Trials

122

all time

Status Distribution
Active(32)
Completed(62)
Terminated(19)
Other(9)

Detailed Status

Completed62
Recruiting18
Terminated14
Active, not recruiting11
unknown8
Withdrawn5

Development Timeline

Analytics

Development Status

Total Trials
122
Active
29
Success Rate
81.6%
Most Advanced
Phase 3

Trials by Phase

Phase 129 (26.1%)
Phase 273 (65.8%)
Phase 35 (4.5%)
N/A4 (3.6%)

Trials by Status

terminated1411%
withdrawn54%
not_yet_recruiting32%
suspended11%
active_not_recruiting119%
recruiting1815%
unknown87%
completed6251%

Recent Activity

Clinical Trials (122)

Showing 20 of 122 trialsScroll for more
NCT02535533Phase 1

SLM + Axitinib for Clear Cell RCC

Completed
NCT05327686Phase 2

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

Recruiting
NCT01744249Phase 2

Sandostatin LAR and Axitinib vs Pbo in Pnts With Advanced Well-differentiated Non-pancreatic Neuroendocrine Carcinomas

Completed
NCT04355156Phase 2

Axitinib Monotherapy With Early Dynamic Contrast Enhanced Ultrasound Monitoring in Chemorefractory Third Line Metastatic Colorectal Cancer

Completed
NCT05059522Phase 3

Continued Access Study for Participants Deriving Benefit in Pfizer-Sponsored Avelumab Parent Studies That Are Closing

Active Not Recruiting
NCT05969496Phase 2

Neoadjuvant Pembrolizumab and Axitinib in Renal Cell Carcinoma With Inferior Vena Cava Tumor Thrombus

Recruiting
NCT07500831Not Applicable

Fasting-Mimicking Diet Combined With IO-TKI Combination Therapy in Patients With Metastatic Renal Cell Carcinoma

Not Yet Recruiting
NCT03297606Phase 2

Canadian Profiling and Targeted Agent Utilization Trial (CAPTUR)

Recruiting
NCT05017012Phase 1

A Study to Evaluate the Bioavailability of Pembrolizumab (MK-3475) Via Subcutaneous (SC) Injection of Pembrolizumab Formulated With Berahyaluronidase Alfa (MK-5180) [MK-3475A] In Advanced Solid Tumors (MK-3475A-C18)

Active Not Recruiting
NCT07123090Phase 2

A Study of Sasanlimab, Palbociclib and Axitinib in Metastatic Renal Cell Carcinoma

Recruiting
NCT04693468Phase 1

Talazoparib and Palbociclib, Axitinib, or Crizotinib for the Treatment of Advanced or Metastatic Solid Tumors, TalaCom Trial

Recruiting
NCT07469683Phase 2

An Open-label, Randomized Phase 2 Clinical Trial to Evaluate the Efficacy and Safety of the Combination Therapy of SLC-3010 and Axitinib Compared to Axitinib Monotherapy as a Second-line Treatment for Locally Advanced or Metastatic Clear Cell Renal Cell Carcinoma

Recruiting
NCT06860386Phase 2

Study of Adaptive Immunotherapy With VEGFR-TKI in Patients With Advanced RCC

Suspended
NCT01409200Phase 2

Antiandrogen Therapy With or Without Axitinib Before Surgery in Treating Patients With Previously Untreated Prostate Cancer With Known or Suspected Lymph Node Metastasis

Completed
NCT03839498Phase 2

Study of Axitinib (AG-013736) With Evaluation of the VEGF-pathway in Pheochromocytoma/Paraganglioma

Active Not Recruiting
NCT05384496Phase 2

Axitinib and Nivolumab for the Treatment of Mucosal Melanoma

Recruiting
NCT05805501Phase 2

A Study of Immune Checkpoint Inhibitor Combinations With Axitinib in Participants With Untreated Locally Advanced Unresectable or Metastatic Renal Cell Carcinoma

Active Not Recruiting
NCT07383441Phase 3

Adding Biotherapy or Placebo to Standard Treatment for Advanced Kidney Cancer

Not Yet Recruiting
NCT02853331Phase 3

Study to Evaluate the Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Axitinib Versus Sunitinib Monotherapy in Participants With Renal Cell Carcinoma (MK-3475-426/KEYNOTE-426)

Completed
NCT04585815Phase 1

Study of Immunotherapy (Sasanlimab) in Combination With Targeted Therapies in People With Advanced Non-small Cell Lung Cancer (NSCLC) (Landscape 1011 Study)

Terminated

Drug Details

Intervention Type
DRUG
Total Trials
122