Success Metrics

Clinical Success Rate
82.3%

Based on 65 completed trials

Completion Rate
82%(65/79)
Active Trials
28(22%)
Results Posted
71%(46 trials)
Terminated
14(11%)

Phase Distribution

Ph not_applicable
4
3%
Ph phase_1
31
25%
Ph phase_2
75
60%
Ph phase_3
5
4%

Phase Distribution

31

Early Stage

75

Mid Stage

5

Late Stage

Phase Distribution115 total trials
Phase 1Safety & dosage
31(27.0%)
Phase 2Efficacy & side effects
75(65.2%)
Phase 3Large-scale testing
5(4.3%)
N/ANon-phased studies
4(3.5%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

77.4%

65 of 84 finished

Non-Completion Rate

22.6%

19 ended early

Currently Active

28

trials recruiting

Total Trials

126

all time

Status Distribution
Active(33)
Completed(65)
Terminated(19)
Other(9)

Detailed Status

Completed65
Recruiting18
Terminated14
Active, not recruiting10
unknown8
Not yet recruiting5

Development Timeline

Analytics

Development Status

Total Trials
126
Active
28
Success Rate
82.3%
Most Advanced
Phase 3

Trials by Phase

Phase 131 (27.0%)
Phase 275 (65.2%)
Phase 35 (4.3%)
N/A4 (3.5%)

Trials by Status

terminated1411%
recruiting1814%
unknown86%
completed6552%
suspended11%
not_yet_recruiting54%
active_not_recruiting108%
withdrawn54%

Recent Activity

Clinical Trials (126)

Showing 20 of 126 trialsScroll for more
NCT03595124Phase 2

A Study to Compare Treatments for a Type of Kidney Cancer Called TFE/Translocation Renal Cell Carcinoma (tRCC)

Active Not Recruiting
NCT05327686Phase 2

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

Recruiting
NCT04693468Phase 1

Talazoparib and Palbociclib, Axitinib, or Crizotinib for the Treatment of Advanced or Metastatic Solid Tumors, TalaCom Trial

Recruiting
NCT07227415Phase 1

Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer

Recruiting
NCT07816770Phase 2

MANTIS-RCC: Toripalimab-Axitinib Induction in TLS-Positive Advanced Non-Clear Cell and Renal Medullary Carcinomas

Not Yet Recruiting
NCT07123090Phase 2

A Study of Sasanlimab, Palbociclib and Axitinib in Metastatic Renal Cell Carcinoma

Recruiting
NCT07776717Phase 2

TACTIC-RCC: Toripalimab Plus Axitinib Induction With Selective Deferred Cytoreductive Nephrectomy in TLS-Positive Advanced Clear Cell Renal Cell Carcinoma

Not Yet Recruiting
NCT05805501Phase 2

A Study of Immune Checkpoint Inhibitor Combinations With Axitinib in Participants With Untreated Locally Advanced Unresectable or Metastatic Renal Cell Carcinoma

Active Not Recruiting
NCT04996823Phase 2

Axitinib + Ipilimumab in Advanced Melanoma

Active Not Recruiting
NCT02912572Phase 2

Avelumab in Patients With MSS, MSI-H and POLE-mutated Recurrent or Persistent Endometrial Cancer and of Avelumab/Talazoparib and Avelumab/Axitinib in Patients With MSS Recurrent or Persistent Endometrial Cancer

Active Not Recruiting
NCT05256472Phase 2

A Study of AK104 Monotherapy or AK104 Plus Axitinib in Advanced/Metastatic Renal Cell Carcinoma

Completed
NCT05059522Phase 3

Continued Access Study for Participants Deriving Benefit in Pfizer-Sponsored Avelumab Parent Studies That Are Closing

Active Not Recruiting
NCT07383441Phase 3

Adding Biotherapy or Placebo to Standard Treatment for Advanced Kidney Cancer

Recruiting
NCT05017012Phase 1

A Study to Evaluate the Bioavailability of Pembrolizumab (MK-3475) Via Subcutaneous (SC) Injection of Pembrolizumab Formulated With Berahyaluronidase Alfa (MK-5180) [MK-3475A] In Advanced Solid Tumors (MK-3475A-C18)

Completed
NCT07630363Phase 1

PTC-Guided Atorvastatin Plus Axitinib and Toripalimab in Advanced RCC

Not Yet Recruiting
NCT05949632Phase 1

A Study of INCB099280 in Combination With Axitinib in Adults With Advanced Solid Tumors

Terminated
NCT04458259Phase 1

Study of PF-07265807 in Participants With Metastatic Solid Tumors.

Terminated
NCT03092856Phase 2

Axitinib With or Without Anti-OX40 Antibody PF-04518600 in Treating Patients With Metastatic Kidney Cancer

Active Not Recruiting
NCT05420220Phase 2

Study of KN046 in Subjects With Advanced Non-Small Cell Lung Cancer

Completed
NCT03172754Phase 1

Study of Nivolumab and Axitinib in Patients With Advanced Renal Cell Carcinoma

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
126