Success Metrics

Clinical Success Rate
82.3%

Based on 65 completed trials

Completion Rate
82%(65/79)
Active Trials
28(23%)
Results Posted
71%(46 trials)
Terminated
14(11%)

Phase Distribution

Ph phase_3
5
4%
Ph not_applicable
4
3%
Ph phase_1
31
25%
Ph phase_2
73
59%

Phase Distribution

31

Early Stage

73

Mid Stage

5

Late Stage

Phase Distribution113 total trials
Phase 1Safety & dosage
31(27.4%)
Phase 2Efficacy & side effects
73(64.6%)
Phase 3Large-scale testing
5(4.4%)
N/ANon-phased studies
4(3.5%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

77.4%

65 of 84 finished

Non-Completion Rate

22.6%

19 ended early

Currently Active

28

trials recruiting

Total Trials

124

all time

Status Distribution
Active(31)
Completed(65)
Terminated(19)
Other(9)

Detailed Status

Completed65
Recruiting18
Terminated14
Active, not recruiting10
unknown8
Withdrawn5

Development Timeline

Analytics

Development Status

Total Trials
124
Active
28
Success Rate
82.3%
Most Advanced
Phase 3

Trials by Phase

Phase 131 (27.4%)
Phase 273 (64.6%)
Phase 35 (4.4%)
N/A4 (3.5%)

Trials by Status

recruiting1815%
suspended11%
terminated1411%
active_not_recruiting108%
unknown86%
withdrawn54%
not_yet_recruiting32%
completed6552%

Recent Activity

Clinical Trials (124)

Showing 20 of 124 trialsScroll for more
NCT04996823Phase 2

Axitinib + Ipilimumab in Advanced Melanoma

Active Not Recruiting
NCT02912572Phase 2

Avelumab in Patients With MSS, MSI-H and POLE-mutated Recurrent or Persistent Endometrial Cancer and of Avelumab/Talazoparib and Avelumab/Axitinib in Patients With MSS Recurrent or Persistent Endometrial Cancer

Active Not Recruiting
NCT07227415Phase 1

Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer

Recruiting
NCT05256472Phase 2

A Study of AK104 Monotherapy or AK104 Plus Axitinib in Advanced/Metastatic Renal Cell Carcinoma

Completed
NCT03595124Phase 2

A Study to Compare Treatments for a Type of Kidney Cancer Called TFE/Translocation Renal Cell Carcinoma (tRCC)

Active Not Recruiting
NCT05327686Phase 2

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

Recruiting
NCT05059522Phase 3

Continued Access Study for Participants Deriving Benefit in Pfizer-Sponsored Avelumab Parent Studies That Are Closing

Active Not Recruiting
NCT07383441Phase 3

Adding Biotherapy or Placebo to Standard Treatment for Advanced Kidney Cancer

Recruiting
NCT05017012Phase 1

A Study to Evaluate the Bioavailability of Pembrolizumab (MK-3475) Via Subcutaneous (SC) Injection of Pembrolizumab Formulated With Berahyaluronidase Alfa (MK-5180) [MK-3475A] In Advanced Solid Tumors (MK-3475A-C18)

Completed
NCT07630363Phase 1

PTC-Guided Atorvastatin Plus Axitinib and Toripalimab in Advanced RCC

Not Yet Recruiting
NCT05949632Phase 1

A Study of INCB099280 in Combination With Axitinib in Adults With Advanced Solid Tumors

Terminated
NCT04458259Phase 1

Study of PF-07265807 in Participants With Metastatic Solid Tumors.

Terminated
NCT03092856Phase 2

Axitinib With or Without Anti-OX40 Antibody PF-04518600 in Treating Patients With Metastatic Kidney Cancer

Active Not Recruiting
NCT05420220Phase 2

Study of KN046 in Subjects With Advanced Non-Small Cell Lung Cancer

Completed
NCT03172754Phase 1

Study of Nivolumab and Axitinib in Patients With Advanced Renal Cell Carcinoma

Active Not Recruiting
NCT05805501Phase 2

A Study of Immune Checkpoint Inhibitor Combinations With Axitinib in Participants With Untreated Locally Advanced Unresectable or Metastatic Renal Cell Carcinoma

Active Not Recruiting
NCT02535533Phase 1

SLM + Axitinib for Clear Cell RCC

Completed
NCT01744249Phase 2

Sandostatin LAR and Axitinib vs Pbo in Pnts With Advanced Well-differentiated Non-pancreatic Neuroendocrine Carcinomas

Completed
NCT04355156Phase 2

Axitinib Monotherapy With Early Dynamic Contrast Enhanced Ultrasound Monitoring in Chemorefractory Third Line Metastatic Colorectal Cancer

Completed
NCT05969496Phase 2

Neoadjuvant Pembrolizumab and Axitinib in Renal Cell Carcinoma With Inferior Vena Cava Tumor Thrombus

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
124