Success Metrics

Clinical Success Rate
73.3%

Based on 11 completed trials

Completion Rate
73%(11/15)
Active Trials
15(39%)
Results Posted
100%(11 trials)
Terminated
4(11%)

Phase Distribution

Ph not_applicable
1
3%
Ph phase_4
2
5%
Ph phase_2
18
47%
Ph phase_1
9
24%
Ph phase_3
5
13%

Phase Distribution

9

Early Stage

18

Mid Stage

7

Late Stage

Phase Distribution35 total trials
Phase 1Safety & dosage
9(25.7%)
Phase 2Efficacy & side effects
18(51.4%)
Phase 3Large-scale testing
5(14.3%)
Phase 4Post-market surveillance
2(5.7%)
N/ANon-phased studies
1(2.9%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

73.3%

11 of 15 finished

Non-Completion Rate

26.7%

4 ended early

Currently Active

15

trials recruiting

Total Trials

38

all time

Status Distribution
Active(20)
Completed(11)
Terminated(4)
Other(3)

Detailed Status

Completed11
Recruiting10
Active, not recruiting5
Terminated4
Not yet recruiting4
unknown2

Development Timeline

Analytics

Development Status

Total Trials
38
Active
15
Success Rate
73.3%
Most Advanced
Phase 4

Trials by Phase

Phase 19 (25.7%)
Phase 218 (51.4%)
Phase 35 (14.3%)
Phase 42 (5.7%)
N/A1 (2.9%)

Trials by Status

terminated411%
active_not_recruiting513%
suspended13%
enrolling_by_invitation13%
not_yet_recruiting411%
unknown25%
completed1129%
recruiting1026%

Recent Activity

Clinical Trials (38)

Showing 20 of 38 trialsScroll for more
NCT06043323Phase 2

A Phase II Study of Axicabtagene Ciloleucel, an Anti-CD19 Chimeric Antigen Receptor (CAR) Tcell Therapy, in Combination With Radiotherapy (RT) in Relapsed/Refractory Follicular Lymphoma

Recruiting
NCT07479797Phase 3

Study Evaluating the Efficacy of KITE-753 Versus Axicabtagene Ciloleucel in Participants With Relapsed or Refractory Large B-Cell Lymphoma After First-Line Therapy

Not Yet Recruiting
NCT07538635Phase 2

CAR-T Combined With ASCT in the Treatment of Relapsed/Refractory Large B-cell Lymphoma With High-risk Factors.

Not Yet Recruiting
NCT05605899Phase 3

Study to Compare Axicabtagene Ciloleucel With Standard of Care Therapy as First-line Treatment in Participants With High-risk Large B-cell Lymphoma

Active Not Recruiting
NCT05077527Phase 1

Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma

Recruiting
NCT04531046Phase 2

Axi-Cel as a 2nd Line Therapy in Patients With Relapsed/Refractory Aggressive B Lymphoma Ineligible to Autologous Stem Cell Transplantation

Active Not Recruiting
NCT02601313Phase 2

Study of Brexucabtagene Autoleucel (KTE-X19) in Participants With Relapsed/Refractory Mantle Cell Lymphoma (Cohort 1 and Cohort 2)

Completed
NCT07042438Phase 2

Fecal Microbiome Transplant to Remodel Intestinal Microbiota for Patients With Relapsed or Refractory Lymphoma With Exposure to High-Risk Antibiotics Who Are Receiving Chimeric Antigen Receptor T Cells

Recruiting
NCT07188558Phase 3

A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy

Recruiting
NCT04205838Phase 2

Anakinra in Preventing Severe Chimeric Antigen Receptor T-Cell Related Encephalopathy Syndrome in Patients With Recurrent or Refractory Large B-cell Lymphoma

Terminated
NCT05041309

Long-term Follow-up Study for Participants of Kite-Sponsored Interventional Studies Treated With Gene-Modified Cells

Enrolling By Invitation
NCT05459571Phase 2

Study of Axicabtagene Ciloleucel Given With Steroids In Participants With Relapsed Or Refractory Large B-Cell Lymphoma

Completed
NCT05633615Phase 2

Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

Recruiting
NCT04855253Phase 1

Ph I/II Study of E7777 Prior to CAR-T for R/R LBCL

Suspended
NCT07326371Phase 2

Glofitamab Combined With CAR-T Therapy in R/R DLBCL

Not Yet Recruiting
NCT03105336Phase 2

A Study of Axicabtagene Ciloleucel in Participants With Relapsed/Refractory Indolent Non-Hodgkin Lymphoma

Completed
NCT03391466Phase 3

Study of Effectiveness of Axicabtagene Ciloleucel Compared to Standard of Care Therapy in Patients With Relapsed/Refractory Diffuse Large B Cell Lymphoma

Completed
NCT05776160

Expanded Access Study for the Treatment of Patients With Commercially Out-of-Specification Axicabtagene Ciloleucel

Unknown
NCT07254754Phase 2

Study to Evaluate the Efficacy of Axicabtagene Ciloleucel in Patients With Late Relapse of Diffuse Large B-Cell Lymphoma

Recruiting
NCT04150913Phase 2

A Phase 2 Trial of Anakinra for the Prevention of CAR-T Cell Mediated Neurotoxicity

Completed

Drug Details

Intervention Type
DRUG
Total Trials
38