Success Metrics

Clinical Success Rate
70.6%

Based on 12 completed trials

Completion Rate
71%(12/17)
Active Trials
0(0%)
Results Posted
58%(7 trials)
Terminated
5(26%)

Phase Distribution

Ph phase_1
7
37%
Ph phase_2
12
63%

Phase Distribution

7

Early Stage

12

Mid Stage

0

Late Stage

Phase Distribution19 total trials
Phase 1Safety & dosage
7(36.8%)
Phase 2Efficacy & side effects
12(63.2%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

66.7%

12 of 18 finished

Non-Completion Rate

33.3%

6 ended early

Currently Active

0

trials recruiting

Total Trials

19

all time

Status Distribution
Completed(12)
Terminated(6)
Other(1)

Detailed Status

Completed12
Terminated5
Withdrawn1
unknown1

Development Timeline

Analytics

Development Status

Total Trials
19
Active
0
Success Rate
70.6%
Most Advanced
Phase 2

Trials by Phase

Phase 17 (36.8%)
Phase 212 (63.2%)

Trials by Status

terminated526%
withdrawn15%
completed1263%
unknown15%

Recent Activity

Clinical Trials (19)

Showing 19 of 19 trials
NCT01772797Phase 1

Phase Ib Study of LDK378 and AUY922 in ALK-rearranged Non-small Cell Lung Cancer

Completed
NCT00708292Phase 1

A Phase I-Ib/II Study to Determine the Maximum Tolerated Dose (MTD) of AUY922 Alone and in Combination With Bortezomib, With or Without Dexamethasone, in Patients With Relapsed or Refractory Multiple Myeloma.

Completed
NCT01402401Phase 2

Phase II of AUY922 in Second-line Gastric Cancer in Combination With Trastuzumab in HER2 Positive Patients

Terminated
NCT01084330Phase 2

Phase II Trial of AUY922 vs. Comparators in Advanced Gastric Cancer

Completed
NCT01613950Phase 1

PI3K Inhibitor BYL719 in Combination With the HSP90 Inhibitor AUY922 in Patients With Advanced or Metastatic Gastric Cancer

Completed
NCT01132625Phase 1

Dose Escalation Study of AUY922 in Advanced Solid Malignancies in Japan

Completed
NCT01271920Phase 1

Combination of AUY922 With Trastuzumab in HER2+ Advanced Breast Cancer Patients Previously Treated With Trastuzumab

Completed
NCT01646125Phase 2

An Open-label, Randomized Phase II Study to Evaluate the Efficacy of AUY922 vs Pemetrexed or Docetaxel in NSCLC Patients With EGFR Mutations

Terminated
NCT01484860Phase 2

Study of AUY922 in Metastatic Pancreatic Cancer Who Are Resistant to First Line Chemotherapy

Terminated
NCT01922583Phase 2

AUY922 in Patient With Stage IV NSCLC

Completed
NCT01854034Phase 2

Phase 2 Study of AUY922 in NSCLC Patients With Exon 20 Insertion Mutations in EGFR

Completed
NCT01752400Phase 2

AUY922 for Advanced ALK-positive NSCLC

Completed
NCT01361945Phase 1

AUY922 With Lapatinib and Letrozole for ER+ HER2+ Advanced Breast Cancer

Withdrawn
NCT01485536Phase 2

A Study of the HSP90 Inhibitor AUY922

Terminated
NCT01404650Phase 2

Study of Hsp90 Inhibitor AUY922 for the Treatment of Patients With Refractory Gastrointestinal Stromal Tumor

Completed
NCT01668173Phase 2

HSP90 Inhibitor, AUY922, in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (Post-PV MF), Post-Essential Thrombocythemia Myelofibrosis (Post-ET MF), and Refractory PV/ET

Terminated
NCT01124864Phase 2

A Study of AUY922 in Non-small-cell Lung Cancer Patients Who Have Received Previous Two Lines of Chemotherapy.

Completed
NCT01294826Phase 1

Study of AUY922 and Cetuximab in Patients With KRAS Wild-Type Metastatic Colorectal Cancer

Completed
NCT01389583Phase 2

A Study of AUY922 for GIST(Gastrointestinal Stromal Tumor) Patients

Unknown

All 19 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
19