Success Metrics

Clinical Success Rate
86.7%

Based on 13 completed trials

Completion Rate
87%(13/15)
Active Trials
5(19%)
Results Posted
15%(2 trials)
Terminated
2(8%)

Phase Distribution

Ph phase_1
7
27%
Ph phase_4
4
15%
Ph phase_2
9
35%
Ph not_applicable
1
4%
Ph phase_3
5
19%

Phase Distribution

7

Early Stage

9

Mid Stage

9

Late Stage

Phase Distribution26 total trials
Phase 1Safety & dosage
7(26.9%)
Phase 2Efficacy & side effects
9(34.6%)
Phase 3Large-scale testing
5(19.2%)
Phase 4Post-market surveillance
4(15.4%)
N/ANon-phased studies
1(3.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

86.7%

13 of 15 finished

Non-Completion Rate

13.3%

2 ended early

Currently Active

5

trials recruiting

Total Trials

26

all time

Status Distribution
Active(7)
Completed(13)
Terminated(2)
Other(4)

Detailed Status

Completed13
unknown4
Recruiting3
Active, not recruiting2
Not yet recruiting2
Terminated2

Development Timeline

Analytics

Development Status

Total Trials
26
Active
5
Success Rate
86.7%
Most Advanced
Phase 4

Trials by Phase

Phase 17 (26.9%)
Phase 29 (34.6%)
Phase 35 (19.2%)
Phase 44 (15.4%)
N/A1 (3.8%)

Trials by Status

completed1350%
active_not_recruiting28%
not_yet_recruiting28%
unknown415%
terminated28%
recruiting312%

Recent Activity

Clinical Trials (26)

Showing 20 of 26 trialsScroll for more
NCT04305054Phase 1

Substudy 02B: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents or Pembrolizumab Alone in Participants With First Line (1L) Advanced Melanoma (MK-3475-02B/KEYMAKER-U02)

Active Not Recruiting
NCT07503730Phase 3

Early Use of Realgar-Indigo Naturalis Formula (RIF) Combined With All-trans Retinoic Acid (ATRA) for Treating Acute Promyelocytic Leukemia (APL).

Recruiting
NCT06484920Phase 2

A Phase II Study of the Combination of Pembrolizumab and ATRA Combination Treatment of Relapsed HL and B-NHL

Recruiting
NCT07348107Phase 1

ATRA and SDK002 in Combination With Chemotherapy and Anti-PD-1 Inhibitor in Patients With Advanced Pancreatic Ductal Adenocarcinoma.

Not Yet Recruiting
NCT04241276Phase 2

A Randomised Trial of ATRA in a Novel Drug Combination for Pancreatic Cancer

Active Not Recruiting
NCT04303169Phase 1

Substudy 02C: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents or Pembrolizumab Alone in Participants With Stage III Melanoma Who Are Candidates for Neoadjuvant Therapy (MK-3475-02C/KEYMAKER-U02)

Completed
NCT04305041Phase 1

Substudy 02A: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents in Participants With Programmed Cell-death 1 (PD-1) Refractory Melanoma (MK-3475-02A/KEYMAKER-U02)

Completed
NCT06371274Not Applicable

A Study on the Efficacy and Safety of Oral All-trans Retinoic Acid Combined With Toripalimab in TNBC.

Recruiting
NCT07079696Phase 2

Investigating the Therapeutic Efficacy of All-trans Retinoic Acid in Autism Spectrum Disorder Patients With 15q11-13 Duplication Syndrome

Not Yet Recruiting
NCT02942758Phase 2

Low-dose AZA, Pioglitazone, ATRA Versus Standard-dose AZA in Patients >=60 Years With Refractory AML

Terminated
NCT02200978Phase 4

A Study for Improving the Outcome of Childhood Acute Promyeloid Leukemia

Completed
NCT04217148Phase 2

The Combination of ATRA and High-dose Dexamethasone as First-line Treatment in Adult Immune Thrombocytopenia

Completed
NCT02020161Phase 4

Clinical Guidelines for APL Treatment

Unknown
NCT03307148Phase 1

Stromal TARgeting for PAncreatic Cancer (STAR_PAC)

Completed
NCT02177812Phase 1

A Phase I Dose Escalation Study of GSK2879552 in Subjects With Acute Myeloid Leukemia (AML)

Terminated
NCT00439673Phase 2

PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS

Completed
NCT02401295Phase 1

ATRA, Celecoxib, and Itraconazole as Maintenance

Completed
NCT01226303Phase 3

Treatment Study for Children and Adolescents With Acute Promyelocitic Leukemia

Unknown
NCT00867672Phase 2

Study of Decitabine Alone or in Combination With Valproic Acid and All-trans Retinoic Acid in Acute Myeloid Leukemia

Completed
NCT00408278Phase 4

Treatment of Newly Diagnosed Patients With Acute Promyelocytic Leukemia (PETHEMA LPA 2005)

Completed

Drug Details

Intervention Type
DRUG
Total Trials
26