Success Metrics

Clinical Success Rate
85.7%

Based on 6 completed trials

Completion Rate
86%(6/7)
Active Trials
14(58%)
Results Posted
50%(3 trials)
Terminated
1(4%)

Phase Distribution

Ph phase_3
4
17%
Ph early_phase_1
1
4%
Ph phase_1
4
17%
Ph phase_2
9
38%
Ph phase_4
1
4%

Phase Distribution

5

Early Stage

9

Mid Stage

5

Late Stage

Phase Distribution19 total trials
Early Phase 1First-in-human
1(5.3%)
Phase 1Safety & dosage
4(21.1%)
Phase 2Efficacy & side effects
9(47.4%)
Phase 3Large-scale testing
4(21.1%)
Phase 4Post-market surveillance
1(5.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

85.7%

6 of 7 finished

Non-Completion Rate

14.3%

1 ended early

Currently Active

14

trials recruiting

Total Trials

24

all time

Status Distribution
Active(16)
Completed(6)
Terminated(1)
Other(1)

Detailed Status

Recruiting8
Active, not recruiting6
Completed6
Not yet recruiting2
Terminated1
unknown1

Development Timeline

Analytics

Development Status

Total Trials
24
Active
14
Success Rate
85.7%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (5.3%)
Phase 14 (21.1%)
Phase 29 (47.4%)
Phase 34 (21.1%)
Phase 41 (5.3%)

Trials by Status

not_yet_recruiting28%
terminated14%
active_not_recruiting625%
completed625%
recruiting833%
unknown14%

Recent Activity

Clinical Trials (24)

Showing 20 of 24 trialsScroll for more
NCT06236724Phase 2

Phase II Study Assessing Efficacy and Safety of Asciminib in Patients With Newly Diagnosed Chronic Myeloid Leukemia in Chronic Phase.

Recruiting
NCT06308588Phase 1

Phase I/II Study of the Combination of Blinatumomab and Asciminib in Patients With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Recruiting
NCT05943522

Asciminib RMP Study

Recruiting
NCT06427811Phase 4

Clinical Study of Asciminib in Previously Treated Indian Patients With Ph+ CML-CP Without T315I Mutation and in Patients With Ph+ CML-CP With T315I Mutation

Completed
NCT03874858Phase 2

A Study of Full Treatment-free Remission in Patients With Chronic Myeloid Leukemia

Completed
NCT06368414Phase 2

A Study of Treatment-free Remission in Chronic Phase Chronic Myeloid Leukemia

Recruiting
NCT07250087Phase 1

Asciminib Maintenance Therapy Following alloHCT or CAR T to Prevent Relapse in Adults With Ph+ALL

Recruiting
NCT07039760Early Phase 1

Asciminib With or Without Sildenafil for Brain Tumors

Not Yet Recruiting
NCT04971226Phase 3

A Study of Oral Asciminib Versus Other TKIs in Adult Patients With Newly Diagnosed Ph+ CML-CP

Active Not Recruiting
NCT04216563Phase 2

ABL001 for the Treatment of Chronic Myeloid Leukemia in Patients Who Are on Therapy With Tyrosine Kinase Inhibitor

Terminated
NCT06629584Phase 2

Phase II Study of Asciminib for Second-line Treatment of Chronic Phase Chronic Myeloid Leukemia

Recruiting
NCT06092879

Asciminib Prospective Non Interventional Study as 3rd Line Therapy or More to Treat Adult Patients With CML- CP in Real World Setting in France

Active Not Recruiting
NCT05456191Phase 3

A Study to Investigate Tolerability and Efficacy of Asciminib (Oral) Versus Nilotinib (Oral) in Adult Participants (≥18 Years of Age) With Newly Diagnosed Philadelphia Chromosome Positive Chronic Myelogenous Leukemia in Chronic Phase (Ph+ CML-CP)

Active Not Recruiting
NCT06684964

RWE,NIS,Prospective Study for the Effectiveness, Tolerability and Adherence of Asciminib in Saudi Arabia. (ASC4REAL)

Recruiting
NCT04360005

Managed Access Programs for ABL001, Asciminib

Unknown
NCT05384587Phase 2

Asciminib Monotherapy, With Dose Escalation, for 2nd and 1st Line Chronic Myelogenous Leukemia

Active Not Recruiting
NCT06409936Phase 2

PEARL Study: PotEntial of Asciminib in the eaRly Treatment of CML

Recruiting
NCT07040982Phase 1

Asciminib as Maintenance Treatment After Cellular Therapies for Adults With Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

Not Yet Recruiting
NCT05413915Phase 3

Asciminib Used in Consolidation With Imatinib vs. Imatinib to Achieve TFR in CP-CML

Active Not Recruiting
NCT04795427Phase 2

Study of Efficacy and Safety of CML-CP Patients Treated With Asciminib Versus Best Available Therapy, Previously Treated With 2 or More Tyrosine Kinase Inhibitors

Completed

Drug Details

Intervention Type
DRUG
Total Trials
24