Success Metrics

Clinical Success Rate
90.0%

Based on 54 completed trials

Completion Rate
90%(54/60)
Active Trials
5(7%)
Results Posted
7%(4 trials)
Terminated
6(9%)

Phase Distribution

Ph phase_1
5
7%
Ph phase_4
34
49%
Ph phase_2
6
9%
Ph not_applicable
7
10%
Ph phase_3
11
16%

Phase Distribution

5

Early Stage

6

Mid Stage

45

Late Stage

Phase Distribution63 total trials
Phase 1Safety & dosage
5(7.9%)
Phase 2Efficacy & side effects
6(9.5%)
Phase 3Large-scale testing
11(17.5%)
Phase 4Post-market surveillance
34(54.0%)
N/ANon-phased studies
7(11.1%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

90.0%

54 of 60 finished

Non-Completion Rate

10.0%

6 ended early

Currently Active

5

trials recruiting

Total Trials

70

all time

Status Distribution
Active(6)
Completed(54)
Terminated(6)
Other(4)

Detailed Status

Completed54
Terminated6
unknown4
Recruiting3
Active, not recruiting2
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
70
Active
5
Success Rate
90.0%
Most Advanced
Phase 4

Trials by Phase

Phase 15 (7.9%)
Phase 26 (9.5%)
Phase 311 (17.5%)
Phase 434 (54.0%)
N/A7 (11.1%)

Trials by Status

active_not_recruiting23%
not_yet_recruiting11%
recruiting34%
completed5477%
terminated69%
unknown46%

Recent Activity

Clinical Trials (70)

Showing 20 of 70 trialsScroll for more
NCT05676645

Pharmacokinetics of Antimalarials in Breastfeeding Ugandan Mother-infant Pairs

Active Not Recruiting
NCT04080895Phase 1

Pharmacokinetic Study of Artemether-lumefantrine and Amodiaquine in Healthy Subjects

Terminated
NCT04009343Phase 2

Pharmacokinetics and Pharmacodynamics of the Gametocytocidal and Post-treatment Chemoprotective Effects of Antimalarials

Active Not Recruiting
NCT06962319Phase 3

Safety of Antimalarials in the FIRst trimEster

Recruiting
NCT03453840Phase 4

Extended Duration Artemether-lumefantrine Treatment for Malaria in Children

Completed
NCT06347471Phase 4

The Transmission of Artemisinin Resistant Parasites Before and After Conventional Artemisinin-combination Therapy

Recruiting
NCT06294912Phase 1

A Study to Evaluate Antimalarial Activity and Safety of MK-7602 in Healthy Adults (MK-7602-003)

Completed
NCT05764746Phase 2

Triple Artemisinin-based Combination Therapy for Delaying Drug Resistance Development - a Randomized Clinical Trial

Recruiting
NCT06076213Phase 4

Test Efficacy Study on the Recommended Antimalarial Drugs in the Democratic Republic of the Congo

Completed
NCT05550909Phase 2

Gametocytocidal and Transmission-blocking Efficacy of ASAQ and ALAQ With or Without PQ in Mali

Completed
NCT06424002Phase 4

The Impact RTS,S/AS01 Vaccine in School Aged Children RTS,S/AS01 Malaria Vaccine in School Aged Children

Not Yet Recruiting
NCT04666350

Clinical Investigation Study to Evaluate the Consistency and Reproducibility of Two Consecutive Mosquito Feeding Assays

Completed
NCT04041973Not Applicable

Study to Assess Efficacy of Artemether-lumefantrine Prophylaxis Against Forest Malaria in Cambodia (PAL_Cambodia)

Completed
NCT05958810

TES of Artemether-lumefantrine for Pf in the Philippines in 2017-2018

Completed
NCT05958693

TES of Artemether-lumefantrine for Pf in the Philippines in 2015

Completed
NCT04708496Phase 4

Optimizing Malaria Treatment for HIV-Malaria Co-infected Individuals

Unknown
NCT05605925Phase 4

Ivermectin-artemisinin Combination Therapy for Eradication of Malaria

Unknown
NCT04618523Phase 4

Safety and Efficacy of Recommended Antimalarial in the Democratic Republic of the Congo

Completed
NCT05081089Phase 2

Gametocytocidal and Transmission-blocking Efficacy of PQ in Combination With AL and TQ in Combination With SPAQ in Mali

Completed
NCT05070520Phase 4

Efficacy of Antimalarial Drugs Used for the Treatment of Uncomplicated Malaria, Plasmodium Falciparum, at the Agadez, Gaya and Tessaoua Sentinel Sites

Completed

Drug Details

Intervention Type
DRUG
Total Trials
70