Success Metrics

Clinical Success Rate
100.0%

Based on 13 completed trials

Completion Rate
100%(13/13)
Active Trials
0(0%)
Results Posted
8%(1 trials)

Phase Distribution

Ph phase_1
7
50%
Ph phase_2
7
50%

Phase Distribution

7

Early Stage

7

Mid Stage

0

Late Stage

Phase Distribution14 total trials
Phase 1Safety & dosage
7(50.0%)
Phase 2Efficacy & side effects
7(50.0%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

92.9%

13 of 14 finished

Non-Completion Rate

7.1%

1 ended early

Currently Active

0

trials recruiting

Total Trials

14

all time

Status Distribution
Completed(13)
Terminated(1)

Detailed Status

Completed13
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
14
Active
0
Success Rate
100.0%
Most Advanced
Phase 2

Trials by Phase

Phase 17 (50.0%)
Phase 27 (50.0%)

Trials by Status

withdrawn17%
completed1393%

Recent Activity

Clinical Trials (14)

Showing 14 of 14 trials
NCT01468922Phase 1

Pazopanib and ARQ 197 for Advanced Solid Tumors

Completed
NCT01152645Phase 2

Study of ARQ 197 Monotherapy

Completed
NCT01656265Phase 1

Study of ARQ 197 in Hepatocellular Carcinoma (HCC)

Completed
NCT01580735Phase 2

ARQ 197 Plus Erlotinib in Patient With Locally Advanced or Metastatic EGFR Mutation-positive Non-small-cell Lung Cancer

Completed
NCT01070290Phase 2

A Study of ARQ 197 Versus Investigator's Choice of Second-Line Chemotherapy in Patients With Locally Advanced or Metastatic Gastric Cancer Who Have Progressive Neoplastic Disease Following Treatment With One Prior Chemotherapy Regimen

Withdrawn
NCT00777309Phase 2

A Randomized Phase 2 Study of Erlotinib + ARQ 197 Versus Erlotinib + Placebo in Previously Treated Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

Completed
NCT00988741Phase 2

Trial of ARQ 197 in Patients With Unresectable Hepatocellular Carcinoma (HCC) Who Have Failed One Prior Systemic Therapy

Completed
NCT00558207Phase 2

A Randomized Phase 2 Study of ARQ 197 Versus Gemcitabine in Treatment-Naïve Patients With Unresectable Locally Advanced or Metastatic Pancreatic Adenocarcinoma

Completed
NCT00557609Phase 2

Phase 2 Study in Patients With MiT Tumors

Completed
NCT00612209Phase 1

A Phase 1 Study of ARQ 197 in Adult Patients With Advanced Solid Tumors

Completed
NCT00612703Phase 1

A Phase 1 Study of ARQ 197 in Adult Patients With Advanced Solid Tumors

Completed
NCT00802555Phase 1

Safety Study of ARQ 197 in Cirrhotic Patients With Hepatocellular Carcinoma (HCC)

Completed
NCT00302172Phase 1

ARQ 197 in Subjects With Metastatic Solid Tumors

Completed
NCT00658554Phase 1

Bioequivalence Study of ARQ 197 Amorphous and Crystalline Polymorphs A and B in Normal Healthy Volunteers

Completed

All 14 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
14