Success Metrics

Clinical Success Rate
95.8%

Based on 68 completed trials

Completion Rate
96%(68/71)
Active Trials
16(16%)
Results Posted
69%(47 trials)
Terminated
3(3%)

Phase Distribution

Ph phase_2
33
33%
Ph not_applicable
3
3%
Ph phase_3
28
28%
Ph phase_4
16
16%
Ph early_phase_1
1
1%
Ph phase_1
8
8%

Phase Distribution

9

Early Stage

33

Mid Stage

44

Late Stage

Phase Distribution89 total trials
Early Phase 1First-in-human
1(1.1%)
Phase 1Safety & dosage
8(9.0%)
Phase 2Efficacy & side effects
33(37.1%)
Phase 3Large-scale testing
28(31.5%)
Phase 4Post-market surveillance
16(18.0%)
N/ANon-phased studies
3(3.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

89.5%

68 of 76 finished

Non-Completion Rate

10.5%

8 ended early

Currently Active

16

trials recruiting

Total Trials

100

all time

Status Distribution
Active(19)
Completed(68)
Terminated(8)
Other(5)

Detailed Status

Completed68
Recruiting10
Active, not recruiting6
unknown5
Withdrawn5
Not yet recruiting3

Development Timeline

Analytics

Development Status

Total Trials
100
Active
16
Success Rate
95.8%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (1.1%)
Phase 18 (9.0%)
Phase 233 (37.1%)
Phase 328 (31.5%)
Phase 416 (18.0%)
N/A3 (3.4%)

Trials by Status

not_yet_recruiting33%
unknown55%
terminated33%
recruiting1010%
withdrawn55%
active_not_recruiting66%
completed6868%

Recent Activity

Clinical Trials (100)

Showing 20 of 100 trialsScroll for more
NCT07325266Phase 2

Human Laboratory Study of Apremilast for Alcohol Use Disorder

Recruiting
NCT05703685Phase 1

[18F]PF-06445974 to Image PDE4B in Major Depressive Disorder Using PET

Recruiting
NCT04804553Phase 3

Apremilast Pediatric Study in Children With Active Juvenile Psoriatic Arthritis

Recruiting
NCT06588738Phase 3

A Study in Patients With Moderate to Severe Plaque Psoriasis to Evaluate the Efficacy and Safety of ESK-001

Completed
NCT06586112Phase 3

A Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Moderate to Severe Plaque Psoriasis

Completed
NCT03036995Phase 2

Repigmentation Using Apremilast and Phototherapy In Diffuse VITILIGO

Completed
NCT04488081Phase 2

I-SPY COVID-19 TRIAL: An Adaptive Platform Trial for Critically Ill Patients

Active Not Recruiting
NCT07432386Phase 4

Methotrexate Versus Apremilast for Pruritus in Psoriasis

Not Yet Recruiting
NCT04227314Phase 3

Randomized Double Blind Controlled Trial Comparing the Safety and Efficacy of Apremilast Versus Placebo in Severe Forms of Recurrent Aphthous Stomatitis

Recruiting
NCT07398651Not Applicable

Apremilast and Adalimumab in Psoriatic Arthritis Patients

Not Yet Recruiting
NCT06324435Phase 1

Apremilast for Alcohol Use Disorder Treatment in Women and Men

Active Not Recruiting
NCT07352566Phase 4

Utilization of a Microdevice for Psoriasis and Atopic Dermatitis

Not Yet Recruiting
NCT07337434Early Phase 1

To Check Comparison of Apremilast and Methotrexate Efficacy in Patients With Moderate to Severe Plaque Psoriasis Presented to Tertiary Care Hospital

Recruiting
NCT06122649Phase 3

A Study to Investigate Efficacy and Safety of Apremilast 30 mg Twice Daily (BID) in Chinese Participants With Moderate to Severe Plaque-type Psoriasis (PsO)

Completed
NCT04175613Phase 3

A Long-term Extension Study of Apremilast (CC-10004) in Pediatric Subjects From 6 Through 17 Years of Age With Moderate to Severe Plaque Psoriasis

Completed
NCT05565560Phase 3

A Study to Assess the Efficacy and Safety of Apremilast in Japanese Pediatric Participants With Moderate to Severe Plaque Psoriasis

Active Not Recruiting
NCT06260904Phase 4

Efficacy and Safety of add-on Apremilast Versus add-on Methotrexate in Patients With Oral Lichen Planus

Completed
NCT04528082Phase 3

Apremilast Pediatric Study in Children With Active Oral Ulcers Associated With Behçet's Disease

Recruiting
NCT05767047Phase 3

A Study of Apremilast in Children With Oral Ulcers Associated With Behçet's Disease or Juvenile Psoriatic Arthritis

Recruiting
NCT06108544Phase 3

A Study About How Well TAK-279 Works and Its Safety in Participants With Moderate-to-severe Plaque Psoriasis During 60 Weeks of Treatment With a Withdrawal and Retreatment Period

Completed

Drug Details

Intervention Type
DRUG
Total Trials
100