Success Metrics

Clinical Success Rate
50.0%

Based on 5 completed trials

Completion Rate
50%(5/10)
Active Trials
2(17%)
Results Posted
200%(10 trials)
Terminated
5(42%)

Phase Distribution

Ph phase_3
1
8%
Ph phase_1
5
42%
Ph phase_2
6
50%

Phase Distribution

5

Early Stage

6

Mid Stage

1

Late Stage

Phase Distribution12 total trials
Phase 1Safety & dosage
5(41.7%)
Phase 2Efficacy & side effects
6(50.0%)
Phase 3Large-scale testing
1(8.3%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

50.0%

5 of 10 finished

Non-Completion Rate

50.0%

5 ended early

Currently Active

2

trials recruiting

Total Trials

12

all time

Status Distribution
Active(2)
Completed(5)
Terminated(5)

Detailed Status

Terminated5
Completed5
Active, not recruiting1
Recruiting1

Development Timeline

Analytics

Development Status

Total Trials
12
Active
2
Success Rate
50.0%
Most Advanced
Phase 3

Trials by Phase

Phase 15 (41.7%)
Phase 26 (50.0%)
Phase 31 (8.3%)

Trials by Status

terminated542%
completed542%
active_not_recruiting18%
recruiting18%

Recent Activity

Clinical Trials (12)

Showing 12 of 12 trials
NCT06508021Phase 2

A Study of Andecaliximab in Participants With Fibrodysplasia Ossificans Progressiva (FOP)

Active Not Recruiting
NCT07024407Phase 1

A Study of Andecaliximab in People With Spinal Cord Injury at Risk for Bone Growth Outside of the Normal Skeleton.

Recruiting
NCT01831427Phase 1

Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of GS-5745 (Andecaliximab) in Adults With Moderate to Severe Active Ulcerative Colitis

Completed
NCT02862535Phase 1

Study to Evaluate the Safety and Tolerability of Andecaliximab as Monotherapy and in Combination With Anti-Cancer Agents in Japanese Participants With Gastric or Gastroesophageal Junction Adenocarcinoma

Terminated
NCT02864381Phase 2

Study to Evaluate the Efficacy and Safety of Andecaliximab Combined With Nivolumab Versus Nivolumab Alone in Adults With Unresectable or Recurrent Gastric or Gastroesophageal Junction Adenocarcinoma

Completed
NCT02077465Phase 1

Safety, Tolerability, and Pharmacokinetics of Andecaliximab in Adults With Chronic Obstructive Pulmonary Disease (COPD)

Completed
NCT01803282Phase 1

Study to Evaluate the Safety and Tolerability of Andecaliximab as Monotherapy and in Combination With Chemotherapy in Participants With Advanced Solid Tumors

Completed
NCT02545504Phase 3

Andecaliximab With mFOLFOX6 as First Line Treatment for Advanced Gastric or Gastroesophageal Junction Adenocarcinoma

Completed
NCT02405442Phase 2

Safety and Efficacy of Andecaliximab in Participants With Moderately to Severely Active Crohn's Disease

Terminated
NCT02520284Phase 2

Safety and Efficacy of Andecaliximab (GS-5745) in Adults With Moderately to Severely Active Ulcerative Colitis

Terminated
NCT02759562Phase 2

Effect of Andecaliximab on FEV1 in Adults With Cystic Fibrosis

Terminated
NCT02862574Phase 2

Andecaliximab as Add-On Therapy to a Tumor Necrosis Factor Inhibitor and Methotrexate Regimen in Adults With Moderately to Severely Active Rheumatoid Arthritis

Terminated

All 12 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
12