Success Metrics

Clinical Success Rate
25.0%

Based on 1 completed trials

Completion Rate
25%(1/4)
Active Trials
29(85%)
Results Posted
600%(6 trials)
Terminated
3(9%)

Phase Distribution

Ph phase_3
6
18%
Ph phase_2
15
44%
Ph phase_1
12
35%

Phase Distribution

12

Early Stage

15

Mid Stage

6

Late Stage

Phase Distribution33 total trials
Phase 1Safety & dosage
12(36.4%)
Phase 2Efficacy & side effects
15(45.5%)
Phase 3Large-scale testing
6(18.2%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

25.0%

1 of 4 finished

Non-Completion Rate

75.0%

3 ended early

Currently Active

29

trials recruiting

Total Trials

34

all time

Status Distribution
Active(29)
Completed(1)
Terminated(3)
Other(1)

Detailed Status

Active, not recruiting15
Recruiting14
Terminated3
Completed1
unknown1

Development Timeline

Analytics

Development Status

Total Trials
34
Active
29
Success Rate
25.0%
Most Advanced
Phase 3

Trials by Phase

Phase 112 (36.4%)
Phase 215 (45.5%)
Phase 36 (18.2%)

Trials by Status

active_not_recruiting1544%
completed13%
recruiting1441%
terminated39%
unknown13%

Recent Activity

Clinical Trials (34)

Showing 20 of 34 trialsScroll for more
NCT06116682Phase 2

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

Recruiting
NCT04487080Phase 3

A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Active Not Recruiting
NCT04988295Phase 3

A Study of Amivantamab and Lazertinib in Combination With Platinum-Based Chemotherapy Compared With Platinum-Based Chemotherapy in Patients With Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non- Small Cell Lung Cancer After Osimertinib Failure

Active Not Recruiting
NCT06385080Phase 1

A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Head and Neck Cancer

Recruiting
NCT06750094Phase 3

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

Recruiting
NCT05379595Phase 1

A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer

Recruiting
NCT07227025Phase 1

A Study of Amivantamab and Olomorasib Combination Therapy in Participants With Metastatic Non-Small Cell Lung Cancer

Recruiting
NCT06662786Phase 3

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

Recruiting
NCT07276399Phase 3

A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer

Recruiting
NCT05498428Phase 2

A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer

Recruiting
NCT02609776Phase 1

Study of Amivantamab, a Human Bispecific EGFR and cMet Antibody, in Participants With Advanced Non-Small Cell Lung Cancer

Active Not Recruiting
NCT06532032Phase 1

A Study of Combination Therapy With Amivantamab and Docetaxel in Participants With Metastatic Non-small Cell Lung Cancer

Active Not Recruiting
NCT05488314Phase 1

A Study of Amivantamab and Capmatinib Combination Therapy in Unresectable Metastatic Non-small Cell Lung Cancer

Active Not Recruiting
NCT04077463Phase 1

A Study of Lazertinib as Monotherapy or in Combination With Amivantamab in Participants With Advanced Non-small Cell Lung Cancer

Active Not Recruiting
NCT05663866Phase 2

Premedication to Reduce Amivantamab Associated Infusion Related Reactions

Active Not Recruiting
NCT04538664Phase 3

A Study of Combination Amivantamab and Carboplatin-Pemetrexed Therapy, Compared With Carboplatin-Pemetrexed, in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Characterized by Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions

Active Not Recruiting
NCT06667076Phase 2

A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

Recruiting
NCT05801029Phase 2

A Study to Investigate Safety and Efficacy of Osimertinib and Amivantamab in Participants With Non-small Cell Lung Cancer With Common Epidermal Growth Factor Receptor Mutations

Active Not Recruiting
NCT05908734Phase 1

A Study of Combination Therapy With Amivantamab and Cetrelimab in Participants With Metastatic Non-small Cell Lung Cancer

Active Not Recruiting
NCT05845450Phase 2

Pre-operative Targeted Treatments in Molecularly Selected Resectable Colorectal Cancer (UNICORN)

Recruiting

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
34