Success Metrics

Clinical Success Rate

76.1%

Based on 35 completed trials

Completion Rate

76%(35/46)

Active Trials

3(4%)

Results Posted

34%(12 trials)

Terminated

11(16%)

Phase Distribution

Ph phase_3

21%

Ph phase_4

22%

Ph phase_1

Ph early_phase_1

Ph not_applicable

19%

Ph phase_2

27%

Phase Distribution

Early Stage

Mid Stage

Late Stage

Phase Distribution65 total trials

Early Phase 1First-in-human

1(1.5%)

Phase 1Safety & dosage

4(6.2%)

Phase 2Efficacy & side effects

18(27.7%)

Phase 3Large-scale testing

14(21.5%)

Phase 4Post-market surveillance

15(23.1%)

N/ANon-phased studies

13(20.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

72.9%

35 of 48 finished

Non-Completion Rate

27.1%

13 ended early

Currently Active

trials recruiting

Total Trials

all time

Status Distribution

Active(5)

Completed(35)

Terminated(13)

Other(14)

Detailed Status

Completed35

unknown14

Terminated11

Recruiting3

Withdrawn2

Not yet recruiting2

Development Timeline

Analytics

Development Status

Total Trials

Active

Success Rate

76.1%

Most Advanced

Phase 4

Trials by Phase

Early Phase 11 (1.5%)

Phase 14 (6.2%)

Phase 218 (27.7%)

Phase 314 (21.5%)

Phase 415 (23.1%)

N/A13 (20.0%)

Trials by Status

terminated1116%

withdrawn23%

not_yet_recruiting23%

unknown1421%

completed3552%

recruiting34%

Recent Activity

3 active trials

Showing 5 of 67

not_yet_recruitingphase_2

Amitriptyline for IBS-like Symptoms in Quiescent Crohn's Disease

NCT07556718

withdrawnearly_phase_1

Comparison of Amitriptyline to Lifestyle Modification as Intervention for Vestibular Migraine

NCT06417684

recruitingnot_applicable

Responding With Evidence and Access for Childhood Headaches

NCT05889624

recruitingphase_2

Evaluating Use of Topical Imipramine and Amitriptyline in Reducing Ultraviolet B Light-Induced Redness in Patients With Rosacea

NCT06312813

completedphase_3

Efficacy of Amitriptyline for Painful Bladder Syndrome (PBS)

NCT00124306

View all 67 trials

Clinical Trials (67)

Showing 20 of 67 trialsScroll for more

NCT07556718Phase 2

Amitriptyline for IBS-like Symptoms in Quiescent Crohn's Disease

Not Yet Recruiting

NCT06417684Early Phase 1

Comparison of Amitriptyline to Lifestyle Modification as Intervention for Vestibular Migraine

Withdrawn

NCT05889624Not Applicable

Responding With Evidence and Access for Childhood Headaches

Recruiting

NCT06312813Phase 2

Evaluating Use of Topical Imipramine and Amitriptyline in Reducing Ultraviolet B Light-Induced Redness in Patients With Rosacea

Recruiting

NCT00124306Phase 3

Efficacy of Amitriptyline for Painful Bladder Syndrome (PBS)

Completed

NCT03472092Phase 2

Mind and Body Approaches to Pain Reduction in Youth With Migraine

Completed

NCT04725383Phase 3

Amitriptyline for Repetitive Behaviors in Autism Spectrum Disorders

Terminated

NCT06245564Not Applicable

Effect of Ketamine, Amitriptyline and Their Combination on Itch

Completed

NCT05279963Not Applicable

EA for BPS: an RCT and Study for Central Mechanism

Recruiting

NCT01856270Phase 2

Amitriptyline to Prevent Headache After Traumatic Brain Injury

Completed

NCT02090998Phase 4

Sphenopalatine Ganglion Nerve Block vs. Elavil for Treatment of Transformed Migraines

Terminated

NCT06499116Phase 4

Comparison of the Effectiveness of First-line Preventive Treatment of Migraine in Primary Care

Not Yet Recruiting

NCT01049347Phase 3

Amitriptyline and Paroxetine Treatment of Major Depression

Completed

NCT06162819Not Applicable

Efficacy of Flunarizine Vs Amitriptyline in Prophylaxis of Migraine Prophylaxis

Unknown

NCT04750967Not Applicable

Amitriptyline vs GON and SON Blocks in Migraine

Completed

NCT05020600

The Effect of Central Sensitization on Treatment Response in Patients With Fibromyalgia

Unknown

NCT04292470Not Applicable

Physiology of GERD and Treatment Response

Completed

NCT03324035Phase 3

Treatment of Neuropathic Pain in Leprosy

Unknown

NCT02552225Phase 2

Treatment of Chronic Laryngitis With Amitriptyline

Terminated

NCT00220844Not Applicable

Tricyclic Antidepressants (TCAs) on Gastric Emptying

Terminated

Drug Details

Intervention Type: DRUG
Total Trials: 67