Success Metrics

Clinical Success Rate
76.1%

Based on 35 completed trials

Completion Rate
76%(35/46)
Active Trials
4(6%)
Results Posted
34%(12 trials)
Terminated
11(15%)

Phase Distribution

Ph not_applicable
13
18%
Ph early_phase_1
1
1%
Ph phase_2
18
25%
Ph phase_1
6
8%
Ph phase_3
14
20%
Ph phase_4
17
24%

Phase Distribution

7

Early Stage

18

Mid Stage

31

Late Stage

Phase Distribution69 total trials
Early Phase 1First-in-human
1(1.4%)
Phase 1Safety & dosage
6(8.7%)
Phase 2Efficacy & side effects
18(26.1%)
Phase 3Large-scale testing
14(20.3%)
Phase 4Post-market surveillance
17(24.6%)
N/ANon-phased studies
13(18.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

72.9%

35 of 48 finished

Non-Completion Rate

27.1%

13 ended early

Currently Active

4

trials recruiting

Total Trials

71

all time

Status Distribution
Active(9)
Completed(35)
Terminated(13)
Other(14)

Detailed Status

Completed35
unknown14
Terminated11
Not yet recruiting5
Recruiting4
Withdrawn2

Development Timeline

Analytics

Development Status

Total Trials
71
Active
4
Success Rate
76.1%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (1.4%)
Phase 16 (8.7%)
Phase 218 (26.1%)
Phase 314 (20.3%)
Phase 417 (24.6%)
N/A13 (18.8%)

Trials by Status

terminated1115%
not_yet_recruiting57%
unknown1420%
withdrawn23%
recruiting46%
completed3549%

Recent Activity

Clinical Trials (71)

Showing 20 of 71 trialsScroll for more
NCT07856056Phase 4

Nortriptyline Compared With Amitriptyline for Migraine Prevention at SQUH

Not Yet Recruiting
NCT07716722Phase 1

Pilot Studies Blocking Injury-Induced MVP Release in Skin Using Topical Amitriptyline

Not Yet Recruiting
NCT05889624Not Applicable

Responding With Evidence and Access for Childhood Headaches

Recruiting
NCT07640061Phase 1

Pilot Studies Testing the Use of Oral Amitriptyline in Reducing Localized Burn Injury-induced Microvesicle Particle Release

Not Yet Recruiting
NCT02090998Phase 4

Sphenopalatine Ganglion Nerve Block vs. Elavil for Treatment of Transformed Migraines

Terminated
NCT07655440Phase 4

Comparing Migraine Preventive Therapies vs. Anti-CGRP Therapies for Tinnitus in Patients With Migraine (COMPACT-PM)

Not Yet Recruiting
NCT07556718Phase 2

Amitriptyline for IBS-like Symptoms in Quiescent Crohn's Disease

Recruiting
NCT06417684Early Phase 1

Comparison of Amitriptyline to Lifestyle Modification as Intervention for Vestibular Migraine

Withdrawn
NCT06312813Phase 2

Evaluating Use of Topical Imipramine and Amitriptyline in Reducing Ultraviolet B Light-Induced Redness in Patients With Rosacea

Recruiting
NCT00124306Phase 3

Efficacy of Amitriptyline for Painful Bladder Syndrome (PBS)

Completed
NCT03472092Phase 2

Mind and Body Approaches to Pain Reduction in Youth With Migraine

Completed
NCT04725383Phase 3

Amitriptyline for Repetitive Behaviors in Autism Spectrum Disorders

Terminated
NCT06245564Not Applicable

Effect of Ketamine, Amitriptyline and Their Combination on Itch

Completed
NCT05279963Not Applicable

EA for BPS: an RCT and Study for Central Mechanism

Recruiting
NCT01856270Phase 2

Amitriptyline to Prevent Headache After Traumatic Brain Injury

Completed
NCT06499116Phase 4

Comparison of the Effectiveness of First-line Preventive Treatment of Migraine in Primary Care

Not Yet Recruiting
NCT01049347Phase 3

Amitriptyline and Paroxetine Treatment of Major Depression

Completed
NCT06162819Not Applicable

Efficacy of Flunarizine Vs Amitriptyline in Prophylaxis of Migraine Prophylaxis

Unknown
NCT04750967Not Applicable

Amitriptyline vs GON and SON Blocks in Migraine

Completed
NCT05020600

The Effect of Central Sensitization on Treatment Response in Patients With Fibromyalgia

Unknown

Drug Details

Intervention Type
DRUG
Total Trials
71