Success Metrics

Clinical Success Rate
85.7%

Based on 36 completed trials

Completion Rate
86%(36/42)
Active Trials
0(0%)
Results Posted
11%(4 trials)
Terminated
6(12%)

Phase Distribution

Ph phase_1
19
37%
Ph phase_3
5
10%
Ph phase_4
1
2%
Ph phase_2
26
51%

Phase Distribution

19

Early Stage

26

Mid Stage

6

Late Stage

Phase Distribution51 total trials
Phase 1Safety & dosage
19(37.3%)
Phase 2Efficacy & side effects
26(51.0%)
Phase 3Large-scale testing
5(9.8%)
Phase 4Post-market surveillance
1(2.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

81.8%

36 of 44 finished

Non-Completion Rate

18.2%

8 ended early

Currently Active

0

trials recruiting

Total Trials

51

all time

Status Distribution
Completed(36)
Terminated(8)
Other(7)

Detailed Status

Completed36
unknown7
Terminated6
Withdrawn2

Development Timeline

Analytics

Development Status

Total Trials
51
Active
0
Success Rate
85.7%
Most Advanced
Phase 4

Trials by Phase

Phase 119 (37.3%)
Phase 226 (51.0%)
Phase 35 (9.8%)
Phase 41 (2.0%)

Trials by Status

completed3671%
terminated612%
unknown714%
withdrawn24%

Recent Activity

0 active trials
Showing 5 of 51
completedphase_1

Combination Chemotherapy, Amifostine, and Peripheral Stem Cell Transplantation in Treating Patients With Stage II, Stage III, or Stage IV Breast Cancer

NCT00003927
terminatedphase_1

Amifostine and Melphalan in Treating Patients With Primary Systemic Amyloidosis Who Are Undergoing Peripheral Stem Cell Transplantation

NCT00052884
withdrawnphase_2

Amifostine & High-Dose Combination Chemotherapy in Treating Patients With Acute ML or CML

NCT00003407
terminatedphase_2

Surgery, Radiation Therapy, and Combination Chemotherapy in Treating Patients With Recurrent Head and Neck Cancer

NCT00003777
withdrawnphase_2

Combination Chemotherapy Plus Biological Therapy in Treating Patients With Acute Myelogenous Leukemia

NCT00003405
View all 51 trials

Clinical Trials (51)

Showing 20 of 51 trialsScroll for more
NCT00003927Phase 1

Combination Chemotherapy, Amifostine, and Peripheral Stem Cell Transplantation in Treating Patients With Stage II, Stage III, or Stage IV Breast Cancer

Completed
NCT00052884Phase 1

Amifostine and Melphalan in Treating Patients With Primary Systemic Amyloidosis Who Are Undergoing Peripheral Stem Cell Transplantation

Terminated
NCT00003407Phase 2

Amifostine & High-Dose Combination Chemotherapy in Treating Patients With Acute ML or CML

Withdrawn
NCT00003777Phase 2

Surgery, Radiation Therapy, and Combination Chemotherapy in Treating Patients With Recurrent Head and Neck Cancer

Terminated
NCT00003405Phase 2

Combination Chemotherapy Plus Biological Therapy in Treating Patients With Acute Myelogenous Leukemia

Withdrawn
NCT00003225Phase 1

Amifostine Plus Irinotecan in Treating Patients With Metastatic Colorectal Cancer

Completed
NCT00003048Phase 2

Amifostine in Treating Patients With Myelodysplastic Syndrome

Completed
NCT00003926Phase 1

Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors

Terminated
NCT00503776Phase 2

Chemo/XRT +/- Amifostine to Assess Outcomes Related to Xerostomia, Mucositis, & Dysphagia

Terminated
NCT00003582Phase 1

Radiation Therapy, Combination Chemotherapy, and Amifostine in Treating Patients With Head and Neck Cancer

Completed
NCT00006012Phase 1

Combination Chemotherapy and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer

Completed
NCT00217438Phase 3

Melphalan and Amifostine Followed By One or Two Autologous or Syngeneic Stem Cell Transplants and Maintenance Therapy in Treating Patients With Stage II-III Multiple Myeloma

Completed
NCT00012012Phase 1

Radiation Therapy and Cisplatin With or Without Amifostine for Patients With Stage IIIB or IVA Cervical Cancer

Completed
NCT00003313Phase 3

Amifostine in Treating Patients With Stage II or Stage III Non-small Cell Lung Cancer

Completed
NCT00098683Phase 2

Amifostine in Treating Young Patients With Newly Diagnosed De Novo Myelodysplastic Syndromes

Completed
NCT00004036Phase 1

Combination Chemotherapy Plus Amifostine in Treating Patients With Advanced Cancer

Unknown
NCT00003827Phase 2

Combination Chemotherapy in Treating Patients With Myelodysplastic Syndrome

Unknown
NCT00004264Phase 1

Docetaxel, Cisplatin, and Amifostine in Treating Patients With Advanced Non-small Cell Lung Cancer

Unknown
NCT00003583Phase 2

Amifostine to Prevent Side Effects in Patients Who Are Receiving Chemotherapy and Radiation Therapy for Limited-Stage Small Cell Lung Cancer

Unknown
NCT00003251Phase 1

Amifostine Plus Chemotherapy and Radiation Therapy in Treating Patients With Advanced, Unresectable Head and Neck Cancer

Unknown

Drug Details

Intervention Type
DRUG
Total Trials
51