Success Metrics

Clinical Success Rate
73.3%

Based on 11 completed trials

Completion Rate
73%(11/15)
Active Trials
0(0%)
Results Posted
55%(6 trials)
Terminated
4(20%)

Phase Distribution

Ph phase_1
5
25%
Ph phase_2
12
60%
Ph phase_3
2
10%
Ph phase_4
1
5%

Phase Distribution

5

Early Stage

12

Mid Stage

3

Late Stage

Phase Distribution20 total trials
Phase 1Safety & dosage
5(25.0%)
Phase 2Efficacy & side effects
12(60.0%)
Phase 3Large-scale testing
2(10.0%)
Phase 4Post-market surveillance
1(5.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

64.7%

11 of 17 finished

Non-Completion Rate

35.3%

6 ended early

Currently Active

0

trials recruiting

Total Trials

20

all time

Status Distribution
Completed(11)
Terminated(6)
Other(3)

Detailed Status

Completed11
Terminated4
unknown3
Withdrawn2

Development Timeline

Analytics

Development Status

Total Trials
20
Active
0
Success Rate
73.3%
Most Advanced
Phase 4

Trials by Phase

Phase 15 (25.0%)
Phase 212 (60.0%)
Phase 32 (10.0%)
Phase 41 (5.0%)

Trials by Status

terminated420%
withdrawn210%
completed1155%
unknown315%

Recent Activity

Clinical Trials (20)

Showing 20 of 20 trials
NCT01998529Phase 1

Study of Cytoreductive Surgery and Hyperthermic Intrathoracic Pleural Chemotherapy (HITC) With Escalating Doses for Children and Adolescents With Unilateral Pleural Malignancy

Completed
NCT00601198Phase 2

A Study of Amifostine (Ethyol) in Patients With Colorectal Cancer

Terminated
NCT00274937Phase 3

Radiation Therapy, Amifostine, and Chemotherapy in Treating Young Patients With Newly Diagnosed Nasopharyngeal Cancer

Completed
NCT05167370Phase 2

High Dose Chemotherapy With Amifostine and Autologous Stem Cell Transplantation for High Risk Relapsed Pediatric Solid Tumors and Brain Tumors

Terminated
NCT01288625Phase 4

Prospective Study of Head and Neck Cancer Radiation Treatment With or Without Amifostine

Withdrawn
NCT00318890Phase 1

Cisplatin and Docetaxel Plus Docetaxel and Radiotherapy With Amifostine for Squamous Cell Carcinoma of the Head and Neck

Completed
NCT03702985Phase 2

Radiation-protection Effect of Amifostine in Locally Advanced Rectal Cancer

Unknown
NCT01364259Phase 3

A Study of Amifostine for Prevention of Facial Numbness in Radiosurgery Treatment of Trigeminal Neuralgia

Terminated
NCT00270790Phase 2

EVALUATION OF AMIFOSTINE FOR MUCOSAL AND HEMOPOETIC PROTECTION AND CARBOPLATIN, TAXOL, RADIOTHERAPY IN THE MANAGEMENT OF PATIENTS WITH HEAD AND NECK CANCER.(GCC 0202)

Completed
NCT00571298Phase 1

Extrapleural Pneumonectomy /Pleurectomy Decortication, IHOC Cisplatin and Gemcitabine With Amifostine and Sodium Thiosulfate Cytoprotection for Resectable Malignant Pleural Mesothelioma

Completed
NCT00003657Phase 2

High-dose ICE With Amifostine

Completed
NCT00095927Phase 2

Randomized Amifostine For SCCHN

Completed
NCT01586117Phase 2

A Phase II Study of Amifostine for the Prevention of Acute Radiation-Induced Rectal Toxicity

Unknown
NCT00137358Phase 1

Radiation With Chemotherapy and a Study Drug to the Para-Aortic Nodes in Cervical Cancer

Withdrawn
NCT00078845Phase 2

Amifostine in Treating Peripheral Neuropathy Caused by Paclitaxel in Patients With Solid Tumors

Completed
NCT00003143Phase 2

Combination Chemotherapy With or Without Amifostine in Treating Patients With Recurrent or Refractory Non-Hodgkin's Lymphoma or Hodgkin's Disease Undergoing Stem Cell Transplantation

Completed
NCT00409331Phase 2

Amifostine With IMRT for Submandibular and Sublingual Salivary Sparing During Head and Neck Cancer Treatment

Terminated
NCT00136474Phase 2

Amifostine for Head and Neck Irradiation in Lymphoma

Completed
NCT00081315Phase 2

Subcutaneous Amifostine (Ethyol®) in the Prevention of Radiochemotherapy-Induced Esophagitis and Pneumonitis in Patients With Unresectable Non-Small Cell Lung Cancer

Completed
NCT00006127Phase 1

Phase I Study of Amifostine in Patients With Bone Marrow Failure Related to Fanconi's Anemia

Unknown

All 20 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
20