Success Metrics

Clinical Success Rate
66.7%

Based on 4 completed trials

Completion Rate
67%(4/6)
Active Trials
1(14%)
Results Posted
125%(5 trials)
Terminated
2(29%)

Phase Distribution

Ph phase_1
7
100%

Phase Distribution

7

Early Stage

0

Mid Stage

0

Late Stage

Phase Distribution7 total trials
Phase 1Safety & dosage
7(100.0%)

Highest Phase Reached

Phase 1

Trial Status & Enrollment

Completion Rate

66.7%

4 of 6 finished

Non-Completion Rate

33.3%

2 ended early

Currently Active

1

trials recruiting

Total Trials

7

all time

Status Distribution
Active(1)
Completed(4)
Terminated(2)

Detailed Status

Completed4
Terminated2
Active, not recruiting1

Development Timeline

Analytics

Development Status

Total Trials
7
Active
1
Success Rate
66.7%
Most Advanced
Phase 1

Trials by Phase

Phase 17 (100.0%)

Trials by Status

terminated229%
active_not_recruiting114%
completed457%

Recent Activity

1 active trials
Showing 5 of 7
active_not_recruitingphase_1

Sotorasib Activity in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation (CodeBreak 101)

NCT04185883
terminatedphase_1

Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (mCRPC)

NCT04631601
completedphase_1

AMG 757 and AMG 404 in Subjects With Small Cell Lung Cancer (SCLC)

NCT04885998
completedphase_1

AMG 404 in Patients With Advanced Solid Tumors

NCT03853109
completedphase_1

Study of AMG 994 Monotherapy and AMG 994 and AMG 404 Combination Therapy in Participants With Advanced Solid Tumors

NCT04727554
View all 7 trials

Clinical Trials (7)

Showing 7 of 7 trials
NCT04185883Phase 1

Sotorasib Activity in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation (CodeBreak 101)

Active Not Recruiting
NCT04631601Phase 1

Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (mCRPC)

Terminated
NCT04885998Phase 1

AMG 757 and AMG 404 in Subjects With Small Cell Lung Cancer (SCLC)

Completed
NCT03853109Phase 1

AMG 404 in Patients With Advanced Solid Tumors

Completed
NCT04727554Phase 1

Study of AMG 994 Monotherapy and AMG 994 and AMG 404 Combination Therapy in Participants With Advanced Solid Tumors

Completed
NCT03296696Phase 1

Study of AMG 596 in Patients With EGFRvIII Positive Glioblastoma

Terminated
NCT04524455Phase 1

Blinatumomab in Combination With AMG 404 for the Treatment of Adults With Relapsed or Refractory B Cell Precursor ALL

Completed

All 7 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
7