Success Metrics

Clinical Success Rate
75.0%

Based on 15 completed trials

Completion Rate
75%(15/20)
Active Trials
2(9%)
Results Posted
60%(9 trials)
Terminated
5(22%)

Phase Distribution

Ph phase_2
4
17%
Ph phase_4
5
22%
Ph phase_3
11
48%
Ph not_applicable
2
9%

Phase Distribution

0

Early Stage

4

Mid Stage

16

Late Stage

Phase Distribution22 total trials
Phase 2Efficacy & side effects
4(18.2%)
Phase 3Large-scale testing
11(50.0%)
Phase 4Post-market surveillance
5(22.7%)
N/ANon-phased studies
2(9.1%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

71.4%

15 of 21 finished

Non-Completion Rate

28.6%

6 ended early

Currently Active

2

trials recruiting

Total Trials

23

all time

Status Distribution
Active(2)
Completed(15)
Terminated(6)

Detailed Status

Completed15
Terminated5
Recruiting2
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
23
Active
2
Success Rate
75.0%
Most Advanced
Phase 4

Trials by Phase

Phase 24 (18.2%)
Phase 311 (50.0%)
Phase 45 (22.7%)
N/A2 (9.1%)

Trials by Status

recruiting29%
withdrawn14%
terminated522%
completed1565%

Recent Activity

2 active trials
Showing 5 of 23
recruitingphase_3

A Study of Surgical Techniques During Cystectomy

NCT06703476
completedphase_4

Alvimopan as a Rescue Treatment of Postoperative Ileus

NCT04405037
recruitingphase_3

Alvimopan Versus Placebo in Patients Undergoing Radical Cystectomy on an Enhanced Recovery Protocol

NCT03216525
terminatedphase_3

Alvimopan as Rescue in Post op Ileus

NCT02742181
terminatedphase_2

Phase 2 RCT of Alvimopan vs. Placebo After CRS/HIPEC

NCT03352414
View all 23 trials

Clinical Trials (23)

Showing 20 of 23 trialsScroll for more
NCT06703476Phase 3

A Study of Surgical Techniques During Cystectomy

Recruiting
NCT04405037Phase 4

Alvimopan as a Rescue Treatment of Postoperative Ileus

Completed
NCT03216525Phase 3

Alvimopan Versus Placebo in Patients Undergoing Radical Cystectomy on an Enhanced Recovery Protocol

Recruiting
NCT02742181Phase 3

Alvimopan as Rescue in Post op Ileus

Terminated
NCT03352414Phase 2

Phase 2 RCT of Alvimopan vs. Placebo After CRS/HIPEC

Terminated
NCT02789111Phase 4

Trial of Alvimopan in Major Spine Surgery

Completed
NCT03068975Phase 4

Alvimopan Use in Polytraumatized Patients

Terminated
NCT02379858Not Applicable

Gastrointestinal Tract Recovery in Patients Undergoing Open Ventral Hernia Repair

Terminated
NCT02218190Not Applicable

Alvimopan and Ileus in PSF

Completed
NCT02785003Phase 4

Ketamine in Colorectal Surgery

Withdrawn
NCT00101998Phase 2

Study Of Alvimopan Drug For Treatment Of Constipation Due To Prescription Pain Medication

Completed
NCT00241722Phase 3

Long-Term Safety Evaluation Of Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain

Completed
NCT00388258Phase 3

Study of Alvimopan for the Management of Opioid-induced Postoperative Bowel Dysfunction/Postoperative Ileus

Completed
NCT01704651Phase 3

Accelerating Gastrointestinal Recovery

Completed
NCT00205842Phase 3

Study of Alvimopan for the Management of Opioid-induced Postoperative Bowel Dysfunction/Postoperative Ileus

Completed
NCT00708201Phase 4

A Study of Alvimopan for the Management of Postoperative Ileus in Participants Undergoing Radical Cystectomy

Completed
NCT00259922Phase 3

Alvimopan For The Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain

Completed
NCT00256932Phase 3

Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain

Completed
NCT00135577Phase 2

Study 767905/008 Extension Study: Alvimopan for Treatment of Opioid-Induced Bowel Dysfunction in Cancer Pain Subjects

Completed
NCT00331045Phase 2

Clinical Evaluation Of Alvimopan (SB767905) On Constipation And Related Symptoms Associated With Opioid

Terminated

Drug Details

Intervention Type
DRUG
Total Trials
23