Success Metrics

Clinical Success Rate
84.6%

Based on 33 completed trials

Completion Rate
85%(33/39)
Active Trials
11(17%)
Results Posted
42%(14 trials)
Terminated
6(10%)

Phase Distribution

Ph phase_1
1
2%
Ph phase_3
22
35%
Ph phase_4
11
17%
Ph not_applicable
5
8%
Ph early_phase_1
1
2%
Ph phase_2
11
17%

Phase Distribution

2

Early Stage

11

Mid Stage

33

Late Stage

Phase Distribution51 total trials
Early Phase 1First-in-human
1(2.0%)
Phase 1Safety & dosage
1(2.0%)
Phase 2Efficacy & side effects
11(21.6%)
Phase 3Large-scale testing
22(43.1%)
Phase 4Post-market surveillance
11(21.6%)
N/ANon-phased studies
5(9.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

78.6%

33 of 42 finished

Non-Completion Rate

21.4%

9 ended early

Currently Active

11

trials recruiting

Total Trials

63

all time

Status Distribution
Active(12)
Completed(33)
Terminated(9)
Other(9)

Detailed Status

Completed33
Recruiting10
unknown9
Terminated6
Withdrawn3
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
63
Active
11
Success Rate
84.6%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (2.0%)
Phase 11 (2.0%)
Phase 211 (21.6%)
Phase 322 (43.1%)
Phase 411 (21.6%)
N/A5 (9.8%)

Trials by Status

withdrawn35%
not_yet_recruiting12%
recruiting1016%
active_not_recruiting12%
unknown914%
completed3352%
terminated610%

Recent Activity

Clinical Trials (63)

Showing 20 of 63 trialsScroll for more
NCT06658197Phase 3

Efficacy and Safety of Tenecteplase Bridging Mechanical Thrombectomy for Acute Large Vessel Occlusion Stroke

Recruiting
NCT07360717Not Applicable

To Compare the Efficacy & Safety of Ultra-Slow (24 hr) Low Dose (25 mg) Infusion of Alteplase Over Slow (24hr) Infusion of Streptokinase in Mechanical Prosthetic Valve Thrombosis

Completed
NCT07003646

Reperfusion Treatment in Acute Pulmonary Embolism

Recruiting
NCT00147316Phase 3

Japan Alteplase Clinical Trial (J-ACT): Efficacy and Safety Study of Tissue Plasminogen Activator (Alteplase) for Ischemic Stroke

Completed
NCT00412867Phase 4

Post-marketing Clinical Study of Alteplase for Acute Ischemic Stroke (Japan Alteplase Clinical Trial Ⅱ:J-ACT Ⅱ)

Completed
NCT05728333Phase 2

Intravenous Tirofiban Versus Alteplase Before Mechanical Thrombectomy in Stroke

Recruiting
NCT06184321Early Phase 1

Alteplase Through an Indwelling Pleural Catheter for the Management of Symptomatic Septated Malignant Pleural Effusion

Recruiting
NCT06337175Phase 4

Predictors of Post-alteplase Hemorrhagic Transformation of Brain Infarction

Completed
NCT04430569Phase 3

Pulmonary Embolism International THrOmbolysis Study-3

Recruiting
NCT04688320Phase 3

Massive Pulmonary Embolism: Trial of Non-immunogenic Recombinant Staphylokinase VS Alteplase FORPE

Completed
NCT03151993Phase 3

Single Bolus Recombinant Nonimmunogenic Staphylokinase (Fortelyzin) and Bolus Infusion Alteplase in Patients With AIS

Completed
NCT04879615Phase 3

24 Hours Treatment with Alteplase in Patients with Ischemic Stroke

Completed
NCT03854500Phase 3

The Norwegian Tenecteplase Stroke Trial 2

Terminated
NCT04915729Phase 3

A Study in Chinese Patients to Compare How Tenecteplase and Alteplase Given After a Stroke Improve Recovering of Physical Activity

Completed
NCT06653946Phase 4

the Predictors of Hemorrhagic Transformation Subtypes in Acute Embolic Stroke Patients

Recruiting
NCT06621121

A Real-world Study of Tenecteplase Versus Alteplase for Thrombolysis in Patients Within 4.5 H of Onset of Ischemic Stroke

Recruiting
NCT03581877Phase 4

Peripheral Systemic Thrombolysis Versus Catheter Directed Thrombolysis for Submassive PE

Active Not Recruiting
NCT05856851Phase 3

Intra-arterial Alteplase for Acute Ischemic Stroke After Mechanical Thrombectomy

Recruiting
NCT03594175Phase 3

Efficacy and Safety of CUSA-081 in the Restoration of Central Venous Access Device (CVAD) Functionality

Terminated
NCT02474810Not Applicable

Intensive Versus Standard Hemodialysis CVC Dysfunction Protocol

Completed

Drug Details

Intervention Type
DRUG
Total Trials
63